Protein Alignment Fdh and Adh1

DIOPT Version :9

• Sequence 1: NP_524310.1
• Gene: Fdh / 41311
• FlyBaseID: FBgn0011768
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_031435.1
• Gene: Adh1 / 11522
• MGIID: 87921
• Length: 375
• Species: Mus musculus
• Alignment Length: 377
• Identity: 211/377 - (55%)
• Similarity: 269/377 - (71%)
• Gaps: 3/377 - (0%)

  Fly     3 ATEGKVITCKAAVAWEAKKPLVIEDIEVAPPKAHEVRIKITATGVCHTDAFTLSGADPEGLFPVV 67
            :|.||||.|||||.||..||..|||||||||||||||||:.|||||.:|...:||.....| |.|
Mouse     2 STAGKVIKCKAAVLWELHKPFTIEDIEVAPPKAHEVRIKMVATGVCRSDDHVVSGTLVTPL-PAV 65

  Fly    68 LGHEGAGIVESVGEGVTNFKAGDHVIALYIPQCNECKFCKSGKTNLCQKIRLTQGAGVMPEGTSR 132
            |||||||||||||||||..|.||.||.|:.|||.||:.||..::|.|.:..|....|.:.|||||
Mouse    66 LGHEGAGIVESVGEGVTCVKPGDKVIPLFSPQCGECRICKHPESNFCSRSDLLMPRGTLREGTSR 130

  Fly   133 LSCKGQQLFHFMGTSTFAEYTVVADISLTKINEKAPLEKVCLLGCGISTGYGAALNTAKVEAGST 197
            .||||:|:.:|:.||||::||||.||::.||:..:||:||||:|||.|||||:|:..|||..|||
Mouse   131 FSCKGKQIHNFISTSTFSQYTVVDDIAVAKIDGASPLDKVCLIGCGFSTGYGSAVKVAKVTPGST 195

  Fly   198 CAVWGLGAVGLAVGLGCKKAGAGKIYGIDINPDKFELAKKFGFTDFVNPKDVADKGSIQNYLIDL 262
            |||:|||.|||:|.:|||.|||.:|..:|||.|||..||:.|.|:.:||:|.:.  .||..|.::
Mouse   196 CAVFGLGGVGLSVIIGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYSK--PIQEVLQEM 258

  Fly   263 TDGGFDYTFECIGNVNTMRSALEATHKGWGTSVVIGVAGAGQEISTRPFQLVVGRVWKGSAFGGW 327
            ||||.|::||.||.::||.|||.:.|...|.|||:||....|.:|..|..|::||.|||:.|||:
Mouse   259 TDGGVDFSFEVIGRLDTMTSALLSCHAACGVSVVVGVPPNAQNLSMNPMLLLLGRTWKGAIFGGF 323

  Fly   328 RSVSDVPKLVEDYLKKDLLVDEFITHELPLSQINEAFDLMHKGESIRSIIKY 379
            :|...|||||.|::.|...:|..|||.||..:|||||||:..|:|||:::.:
Mouse   324 KSKDSVPKLVADFMAKKFPLDPLITHVLPFEKINEAFDLLRSGKSIRTVLTF 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fdh	NP_524310.1	FrmA	9..379	CDD:223990	207/369 (56%)
		alcohol_DH_class_III	9..378	CDD:176260	207/368 (56%)
Adh1	NP_031435.1	alcohol_DH_class_I_II_IV	3..375	CDD:176259	211/374 (56%)
		FrmA	8..375	CDD:223990	207/369 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	79	1.000	Domainoid score	I8648
eggNOG	1	0.900	-	-		E1_COG1062
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D324108at33208
OrthoFinder	1	1.000	-	-		FOG0000360
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100471
Panther	1	1.100	-	-	O	PTHR43880
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.780