Protein Alignment Fdh and Adh6b

DIOPT Version :10

• Sequence 1: NP_524310.1
• Gene: Fdh / 41311
• FlyBaseID: FBgn0011768
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_001357786.1
• Gene: Adh6b / 100417514
• MGIID: 2446626
• Length: 384
• Species: Mus musculus
• Alignment Length: 376
• Identity: 175/376 - (46%)
• Similarity: 251/376 - (66%)
• Gaps: 7/376 - (1%)

  Fly     4 TEGKVITCKAAVAWEAKKPLVIEDIEVAPPKAHEVRIKITATGVCHTDAFTLSG--ADPEGLFPV 66
            |...||.|:|||||....||.||::||.||||.|||:||.|:|:|.||..||.|  ..|   |||
Mouse    10 TSSNVIRCRAAVAWTTNAPLSIEEVEVDPPKAGEVRVKIIASGICGTDNHTLEGKMKTP---FPV 71

  Fly    67 VLGHEGAGIVESVGEGVTNFKAGDHVIALYIPQCNECKFCKSGKTNLCQKIRLTQGAGVMPEGTS 131
            :|||||||:|||||.|||..|.||.|:...:|:|.||.:|...|.|.|:|..:....|:|.:|||
Mouse    72 ILGHEGAGVVESVGPGVTTVKPGDKVLMFPLPECRECFYCLYPKGNFCEKENILSPTGLMLDGTS 136

  Fly   132 RLSCKGQQLFHFMGTSTFAEYTVVADISLTKINEKAPLEKVCLLGCGISTGYGAALNTAKVEAGS 196
            |.:|:|:::::.||||||.|||||.:|::.||...||::.||::.|.:.||:||..|||:|..||
Mouse   137 RFTCRGKKIYNIMGTSTFTEYTVVHEIAVAKIEAAAPMDTVCIMSCAVPTGFGAVFNTAQVTPGS 201

  Fly   197 TCAVWGLGAVGLAVGLGCKKAGAGKIYGIDINPDKFELAKKFGFTDFVNPKDVADKGSIQNYLID 261
            :|.|:|||.:|.|:.:.||.:||.:|.|:|||.:||..|:..|.||.:||..:  |..:|..:.:
Mouse   202 SCVVFGLGGIGSAIVMACKASGACRIIGVDINEEKFPRARALGVTDCLNPNKL--KKPVQEVVKE 264

  Fly   262 LTDGGFDYTFECIGNVNTMRSALEATHKGWGTSVVIGVAGAGQEISTRPFQLVVGRVWKGSAFGG 326
            :|..|.|:.||.||.:.||.:||::.::.:|..|::|||..|.::|..|..|:.||..|.|..||
Mouse   265 MTGVGVDFAFEAIGLIETMVAALKSCNRSYGVCVIMGVAPTGSQLSFDPLVLLPGRTLKSSVLGG 329

  Fly   327 WRSVSDVPKLVEDYLKKDLLVDEFITHELPLSQINEAFDLMHKGESIRSII 377
            :::..|:||||.||::|.:.:|..|||.||..:|||.|.|:.:|:.||.::
Mouse   330 YKTRDDIPKLVTDYVQKKINIDPLITHRLPFPKINEGFRLLQEGKCIRCVL 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fdh	NP_524310.1	alcohol_DH_class_III	9..378	CDD:176260	173/371 (47%)
Adh6b	NP_001357786.1	MDR	10..382	CDD:450120	175/376 (47%)