Protein Alignment Tsp86D and TSPAN15

DIOPT Version :10

• Sequence 1: NP_001262468.1
• Gene: Tsp86D / 41310
• FlyBaseID: FBgn0037848
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_036471.1
• Gene: TSPAN15 / 23555
• HGNCID: 23298
• Length: 294
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 91/267 - (34%)
• Similarity: 147/267 - (55%)
• Gaps: 28/267 - (10%)

  Fly    20 YPHHFSYVSSCVKYMIFLLNFLFWLFGGLLLAIGVYAFMDKLMDGNGWLRLDTIYDVIFNISLVM 84
            |...|||:  .:|:.:.:.:.:|||.|.|:|::|:||.:::       .:..|:.......::::
Human    11 YCARFSYL--WLKFSLIIYSTVFWLIGALVLSVGIYAEVER-------QKYKTLESAFLAPAIIL 66

  Fly    85 IIAGVIVFTVSFAGCLGALRENTWLLKLYSMCLLLFFILEMSLAIICFVFPQYMNSFLEYQFTDK 149
            |:.||::|.|||.|.|.:||:|.:||:.:...|.:..|:|:...::...|......||    .|.
Human    67 ILLGVVMFMVSFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFL----NDN 127

  Fly   150 I---IHSYRDDSDLQNFIDFAQQEFNCCGLSNAGYQDWSKNEYFNCSSPSVERCGVPYSCCI-NA 210
            |   |.:|.||.|.:|.:||.|::|.|||  ...|:|||||:|.:||:|....|||||:||| |.
Human   128 IRRGIENYYDDLDFKNIMDFVQKKFKCCG--GEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNT 190

  Fly   211 TDISSGLVNIMCGYGVQVRSVAAASKRIWTSGCIEIVRVWVERNLYVIAGVALGIALLQ-----L 270
            |::    ||.||||....:...:....|:..||...|.:|...|..::||:.|||.|.|     |
Human   191 TEV----VNTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLL 251

  Fly   271 FVIYLAK 277
            .::|:.:
Human   252 TLLYITR 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp86D	NP_001262468.1	Tetraspanin	51..279	CDD:459767	80/236 (34%)
		penumbra_like_LEL	132..255	CDD:239411	49/126 (39%)
TSPAN15	NP_036471.1	Tetraspanin	20..>157	CDD:459767	46/149 (31%)
		penumbra_like_LEL	114..231	CDD:239411	49/126 (39%)