Protein Alignment CG6574 and slc19a3a

DIOPT Version :10

• Sequence 1: NP_650029.1
• Gene: CG6574 / 41308
• FlyBaseID: FBgn0037846
• Length: 444
• Species: Drosophila melanogaster
• Sequence 2: XP_686091.3
• Gene: slc19a3a / 557854
• ZFINID: ZDB-GENE-110411-41
• Length: 501
• Species: Danio rerio
• Alignment Length: 485
• Identity: 151/485 - (31%)
• Similarity: 249/485 - (51%)
• Gaps: 47/485 - (9%)

  Fly     1 MKEWLKISCLLCVFGCIREIRPSEPYVTEYLLGPWRNITEQQLTHDVYPVGTYSYLVQLVFVFLI 65
            ||:|...:.||.::|....::|.||::..:|.||.:|:|.:||.:.::||.|||||..||.|||:
Zfish     8 MKDWKYPTSLLFIYGFFSTVKPLEPFLYPFLTGPDKNLTTEQLNNQIFPVWTYSYLAVLVPVFLL 72

  Fly    66 TDFLRYKPLIITIGAAGVIIWSMLIWTTSLLSLQILEFFFGTYMAAEVAYYTYIYAKVDKKYYAR 130
            ||:|||||:::..........|||:|...:..:|.::|.:|...:.:|||:||||:.|:.|:|.:
Zfish    73 TDWLRYKPVVVFQSLILFCTTSMLLWCNGVPEMQAMQFTYGVVTSCDVAYFTYIYSMVEIKHYLK 137

  Fly   131 VTSHTRAAMFAGKLVSGITSQLMLNLELMNYKELNYITLGTQIIAMLWAFGLPRVDRSLYFHREQ 195
            .||:.|.|...|..|..:..|::::||||:|..:...||....|||:.:..||....|::||::|
Zfish   138 ATSYCRTAHLLGYTVGSVLGQILVSLELMSYNNILVFTLVLTGIAMIASILLPMPKVSMFFHKKQ 202

  Fly   196 ------------LSITEPQTQLPGVGNLAEM--DQQQENTQKQPGALS----------------- 229
                        :...||:   .|.|.:.::  |.:.:.|:.|...|.
Zfish   203 SEEDDNEGHSGNVKPLEPE---EGFGTMVDLSNDVKVDETKWQQDVLDGSNGCDSSSAKSSKSSR 264

  Fly   230 ---------LLWLHFRNAYTNPRVVQWSLWYAIGLAGYLQVTYYVQVLWKVIEPEP-VIAWNGAV 284
                     .||..|...:::..::.||.|:|:...||.|...|||.||:.:||.. ...:||..
Zfish   265 KAGCGDVLLRLWRDFLQCFSSRTLLLWSAWWALATCGYNQTVNYVQSLWEHVEPSSNFTVYNGGA 329

  Fly   285 DAVLTALAALSALAAGYLHTGRLRPRASLLILGILSAVEGGCVLICCWTQDIYWSYAGFVLFGAL 349
            :|:.....|.:|...|.  :.....|...:.|..|||:|||.:....::.:|:..|.|::||.:|
Zfish   330 EALSNLFGAAAAYGIGL--SSADWSRWGEMALSALSALEGGALFAMVFSGNIWVCYGGYILFKSL 392

  Fly   350 YGFTITVASAEVARNLEEESFGLVFGVNTFVALIFQSLLTIIFVTDTGFELDPVGQYTAYAFYFI 414
            |...||:|..::|..|..|.:.||||.|||.||:.|:::|.:.|...|..:|.|.|:.....||.
Zfish   393 YMLLITIAMFQIAAGLNMERYALVFGANTFCALVLQTIITSVVVDSRGLGVDVVTQFIINGAYFS 457

  Fly   415 GVGVLYLISVLIEYLMCRNNDVEKLENSLD 444
            .:.|::.:..|.. .|||..:.:....:|:
Zfish   458 VIAVIFFLRGLYT-TMCRKPETDTSRENLE 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6574	NP_650029.1	Folate_carrier	2..407	CDD:460318	142/445 (32%)
slc19a3a	XP_686091.3	Folate_carrier	9..451	CDD:460318	142/446 (32%)