Protein Alignment CG6574 and Slc19a3

DIOPT Version :10

• Sequence 1: NP_650029.1
• Gene: CG6574 / 41308
• FlyBaseID: FBgn0037846
• Length: 444
• Species: Drosophila melanogaster
• Sequence 2: XP_038939614.1
• Gene: Slc19a3 / 316559
• RGDID: 1311413
• Length: 485
• Species: Rattus norvegicus
• Alignment Length: 461
• Identity: 156/461 - (33%)
• Similarity: 252/461 - (54%)
• Gaps: 36/461 - (7%)

  Fly     4 WLKISCLLCVFGCIREIRPSEPYVTEYLLGPWRNITEQQLTHDVYPVGTYSYLVQLVFVFLITDF 68
            |:..:.:||:||.....||||.::..:|.||.:|:|..::|:::.||.|||||..|..||::||:
  Rat    15 WVYPTVILCLFGFFSMFRPSESFLIPFLSGPSKNLTSTEMTNEILPVWTYSYLAMLPPVFVLTDY 79

  Fly    69 LRYKPLIITIGAAGVIIWSMLIWTTSLLSLQILEFFFGTYMAAEVAYYTYIYAKVDKKYYARVTS 133
            |||||:|:....|..|.:..|::..|::.:|..|||||...|.|:||:.|||:.|..::|.:|:|
  Rat    80 LRYKPIIMLHVMAFTICYLFLLFGQSVMLMQTAEFFFGIVSATEIAYFAYIYSMVSPEHYQKVSS 144

  Fly   134 HTRAAMFAGKLVSGITSQLMLNLELMNYKELNYITLGTQIIAMLWAFGLPRVDRSLYFH----RE 194
            :.|:..........:.:||:::|..:.|..|.||:|....:|...:..||...:|::||    ||
  Rat   145 YCRSITLVSYTAGSVLAQLLVSLMNVPYSTLFYISLACVSVAFFVSLFLPMPKKSMFFHTKPNRE 209

  Fly   195 QL-SITEPQTQLPGVGNLAEM-----------DQQQENTQKQPGALSLLWLH-FRNAYTNPRVVQ 246
            .. ...||.|.|....|....           |::|:|:..:   :.:.|.. .:..|::..:|.
  Rat   210 ACPKPLEPCTVLKEAHNNGAQPELFANAQNLGDREQDNSALR---IFVYWFQDLKECYSSKHLVY 271

  Fly   247 WSLWYAIGLAGYLQVTYYVQVLWKVIEP-EPVIAWNGAVDAVLTALAALSALAAGYLHT-----G 305
            ||||:|...|||.|:..:|||||:...| :....:||||:|:.|...||::.:.||:..     |
  Rat   272 WSLWWAFATAGYNQILNFVQVLWEQKAPSKDSSIYNGAVEAIATFGGALASFSVGYIKVDWDLLG 336

  Fly   306 RLRPRASLLILGILSAVEGGCVLICCWTQDIYWSYAGFVLFGALYGFTITVASAEVARNLEEESF 370
            .|.       |.:.|||..|.:|:..:|..|:..|.|:||..:.|.|.||:|..::|.||..|.:
  Rat   337 ELG-------LAVFSAVVAGSLLLMNYTLSIWVCYTGYVLVKSSYSFLITIAVFQIAVNLSLERY 394

  Fly   371 GLVFGVNTFVALIFQSLLTIIFVTDTGFELDPVGQYTAYAFYFIGVGVLYLI-SVLIEY-LMCRN 433
            .||||::||:||:.|:::|:|.....|.:|....|:..|..||..:..::|| |:.|.| ..||
  Rat   395 ALVFGIDTFIALVIQTIMTMIVADQRGLQLPVTTQFLVYGSYFAVIAGVFLIRSIYILYSAKCR- 458

  Fly   434 NDVEKL 439
            .:|:.|
  Rat   459 KEVQNL 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6574	NP_650029.1	Folate_carrier	2..407	CDD:460318	144/425 (34%)
Slc19a3	XP_038939614.1	Folate_carrier	14..432	CDD:460318	144/426 (34%)