Protein Alignment CG14694 and slc19a3.2

DIOPT Version :10

• Sequence 1: NP_650028.1
• Gene: CG14694 / 41307
• FlyBaseID: FBgn0037845
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: NP_001039201.1
• Gene: slc19a3.2 / 734059
• XenbaseID: XB-GENE-5732458
• Length: 488
• Species: Xenopus tropicalis
• Alignment Length: 439
• Identity: 147/439 - (33%)
• Similarity: 244/439 - (55%)
• Gaps: 31/439 - (7%)

  Fly     4 WLKISCLLCIFGFLRELRPSEPYHAEILMGEWYHVTQDEVNRSVYPVGTYSYLALLIFVFLITDL 68
            |...:.|||:|||..::|..:|:.|:...|.::::|.::|..||.||.||||:||||.|||:||.
 Frog    12 WKYPTILLCLFGFFADMRAVDPFTAQYFTGSYHNLTVEQVKNSVLPVWTYSYIALLIPVFLLTDY 76

  Fly    69 LRYKPVIIANATTGICIWGTLIWTTT-LSGLQAVEVFYGFYQAGEVAYYSYIYAKVDKQYYPRVT 132
            |||||:|:..| .|:.|...|:..|. .:.:|.:|..|..:.:.:||||||||:.||..||.|||
 Frog    77 LRYKPIIVLQA-LGLSISMLLMLITRGEAAMQGMEFAYAIFSSCDVAYYSYIYSMVDIVYYQRVT 140

  Fly   133 SHTRAAMFVGKLVAGILAQMVIGMRWMNYKQLFYITVTSQVAALLWAFFLPKVEKSLYFHN---- 193
            |:.|:...|...:..:|.|:::....::|..|..:|:||.:.:|:.:.|||...:|::||.
 Frog   141 SYCRSITLVAATLGALLQQILMSFAGVSYFYLNILTLTSALVSLVCSMFLPVPSRSMFFHKKMPG 205

  Fly   194 --------RSEAIEGGTKSDGGNLEKGSEQPSNEEASQEKKIPALQLLWSHFRSAYTNPLVIQWS 250
                    ||..:|   .::..|:.||.|.   |.||.......:.||....:..|.:..::.||
 Frog   206 DTILSKQARSPKME---TTEDTNMLKGCEA---ERASNTNFFNVIWLLCKEVKECYWSRKILYWS 264

  Fly   251 LWYAISLAGFLQITTYMQVVWKSFENEPTI-AWNGAVDVALTLLSAVFALLAGYFHAGRLNTRSS 314
            ||:|.:...:..:..|.|::|...|....| |:|.|||.|.|.|.|:.::.||:     :.....
 Frog   265 LWWAFATPIYNLLVNYSQLLWVYVEPSGKINAYNSAVDAASTFLGAILSMGAGF-----VKVDCE 324

  Fly   315 LL---SMALLSVLEGGCVLLSCWTDDIYLSYLGYVLYGGLFAFTITVASSELASSLEEDSFALVF 376
            |.   ::..||:::.|.:|...::..:::||.||:::...:...||:|:..:|.:|..:.:||:|
 Frog   325 LFGEAALTCLSIIDAGVLLFMGFSRTVWISYAGYLIFKSSYMLLITIATFNIAVNLSMERYALLF 389

  Fly   377 GFNTFVGLLLQCILTFVVVSEKANLNLNVFQQFSVYAFYFIVIGIVYSI 425
            ||||.|.|.:|.:||.||  :...|.|::..||.||..||.|:.:::.:
 Frog   390 GFNTLVALFIQTLLTVVV--DHRRLGLDLITQFLVYGSYFSVVAVMFML 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14694	NP_650028.1	Folate_carrier	2..411	CDD:460318	142/423 (34%)
slc19a3.2	NP_001039201.1	Folate_carrier	10..422	CDD:460318	142/423 (34%)