Protein Alignment CG14694 and Slc19a2

DIOPT Version :10

• Sequence 1: NP_650028.1
• Gene: CG14694 / 41307
• FlyBaseID: FBgn0037845
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: NP_001025195.1
• Gene: Slc19a2 / 289175
• RGDID: 1308611
• Length: 498
• Species: Rattus norvegicus
• Alignment Length: 473
• Identity: 163/473 - (34%)
• Similarity: 258/473 - (54%)
• Gaps: 38/473 - (8%)

  Fly     2 ESWLKISCLLCIFGFLRELRPSEPYHAEILMGEWYHVTQDEVNRSVYPVGTYSYLALLIFVFLIT 66
            |.|...:.|||.:||...||||||:....|:|...::|:.:|...:|||.|||||.||..|||.|
  Rat    28 ECWFLPTALLCAYGFFANLRPSEPFLTPYLLGPDKNLTERQVFNEIYPVWTYSYLLLLFPVFLAT 92

  Fly    67 DLLRYKPVIIANATTGICIWGTLIWTTTLSGLQAVEVFYGFYQAGEVAYYSYIYAKVDKQYYPRV 131
            |.|||||||:....:.|..|..|::...|..:|.:|.|||...|.|:|||||||..||...|.:|
  Rat    93 DYLRYKPVILLQGLSLIVTWFMLLYAQGLLAVQFLEFFYGIATATEIAYYSYIYTVVDLGMYQKV 157

  Fly   132 TSHTRAAMFVGKLVAGILAQMVIGMRWMNYKQLFYITVTSQVAALLWAFFLPKVEKSLYFHNRSE 196
            ||:.|:|..||..|..:|.|:::.:...:...|..:::|....|...|:|||..:|||:||:...
  Rat   158 TSYCRSATLVGFTVGSVLGQILVSVVGWSLFSLNVLSLTCVSVAFAVAWFLPMPQKSLFFHHIPS 222

  Fly   197 AIEG--GTKSDGGNLEKGS--------------------EQPSNEEASQEK--KIPALQLLWSHF 237
            :..|  |.|...|.:...:                    ::|..||..:.|  ::...::||:.|
  Rat   223 SCHGVNGLKVQNGGITTDTPASNHLPGWEDIESKIPLNLDEPPVEEPEEPKPDRLRVFKVLWNDF 287

  Fly   238 RSAYTNPLVIQWSLWYAISLAGFLQITTYMQVVW-KSFENEPTIAWNGAVDVALTLL--SAVFAL 299
            ...|::..::.||:|:|:|..|:.|:..|.|.:| |...::..:.:||.|:...|||  |||||:
  Rat   288 LMCYSSRPLLCWSVWWALSTCGYFQVVNYAQGLWEKVMPSQNAVIYNGGVEAVSTLLGASAVFAV 352

  Fly   300 LAGYFHAGRLNTRS-SLLSMALLSVLEGGCVLLSCWTDDIYLSYLGYVLYGGLFAFTITVASSEL 363
              ||.   :|:..: ..:::.|.|:|....|.:....::|::.|..||::..::...||:|:.::
  Rat   353 --GYI---KLSWSTWGEVTLFLCSLLIAAAVYIMDTVENIWVCYASYVVFRIIYMVLITIATFQI 412

  Fly   364 ASSLEEDSFALVFGFNTFVGLLLQCILTFVVVSEKANLNLNVFQQFSVYAFYFIVIGIVYSIAVI 428
            |::|..:.:|||||.|||:.|.||.:||.:||..: .|.|.:..||.:||.||..|.:|:    :
  Rat   413 AANLSMERYALVFGVNTFIALALQTLLTLIVVDAR-GLGLCIITQFLIYASYFAAISVVF----L 472

  Fly   429 LQYIWSISKKPKAIQEAN 446
            ...|.||.||.:..::.|
  Rat   473 ANGIVSIVKKCRKQEDPN 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14694	NP_650028.1	Folate_carrier	2..411	CDD:460318	151/436 (35%)
Slc19a2	NP_001025195.1	Folate_carrier	28..459	CDD:460318	151/436 (35%)