Protein Alignment CG14694 and slc19a1

DIOPT Version :9

• Sequence 1: NP_650028.1
• Gene: CG14694 / 41307
• FlyBaseID: FBgn0037845
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: XP_002932056.1
• Gene: slc19a1 / 100487033
• XenbaseID: XB-GENE-949159
• Length: 538
• Species: Xenopus tropicalis
• Alignment Length: 465
• Identity: 147/465 - (31%)
• Similarity: 255/465 - (54%)
• Gaps: 46/465 - (9%)

  Fly     2 ESWLKISCLLCIFGFLRELRPSEPYHAEILMGEWYHVTQDEVNRSVYPVGTYSYLALLIFVFLIT 66
            :.|..:...|||:||:.:|||.|.:....|:....:.|:::|...:.||.:|||:|:|:.|||:|
 Frog    75 KQWKFLLFYLCIYGFMTQLRPGESFITPYLLSPERNFTKEQVTNEITPVLSYSYMAVLVPVFLLT 139

  Fly    67 DLLRYKPVIIANATTGICIWGTLIWTTTLSGLQAVEVFYGFYQAGEVAYYSYIYAKVDKQYYPRV 131
            |.||||||:|..:.:.|.:|..||:.|.:..:|.:|.|||...|..|||.|||::.|....|.|.
 Frog   140 DYLRYKPVLILQSLSHISVWLLLIFGTDVIAMQFMEFFYGITMAARVAYSSYIFSLVSPTNYQRA 204

  Fly   132 TSHTRAAMFVGKLVAGILAQMVIGMRWMNYKQLFYITVTSQVAALLWAFFLPKVEKSLYFHNRSE 196
            ..::|:::.:|...:.:|.|:.|.:..:.:|.|.||::......|:...||.:.|:||:| |:|.
 Frog   205 AGYSRSSVLMGVFTSAVLGQLCISLAGVPFKTLNYISLGFMALGLILTLFLKRPERSLFF-NKSI 268

  Fly   197 AIEGGTKSDGGNLEKGSEQPSNEEASQEKK-IPALQL--------------LWSHFRSAYTNPLV 246
                            |:|.:....|:|:| ||..:.              :....:....||.:
 Frog   269 ----------------SKQENGIHLSEEQKAIPGAKTGGFCSGCRNFVIIRMLMELKGTVRNPRL 317

  Fly   247 IQWSLWYAISLAGFLQITTYMQVVWKSFENEPTI----AWNGAVDVALTLLSAVFALLAGYFHAG 307
            ..||||:..:.||:..:..|:|::|.:.  .|||    .:||.||.|.|||.|:.:..||:...
 Frog   318 RLWSLWWIFNSAGYYLMLYYVQILWNTI--YPTIDNRKVYNGGVDAASTLLGAITSFAAGHIKI- 379

  Fly   308 RLNTRSSLLSMALLSVLEGGCVLLSCWTDDIYLSYLGYVLYGGLFAFTITVASSELASSLEEDSF 372
            |.|..|.|: :.|::..:.|.::|...|::|::.|:.|||:...:.|.:.:|..::||:|.::..
 Frog   380 RWNLWSELV-IGLVTAFQAGLLILMNTTENIWVCYVAYVLFRSSYQFLVPIAIFQIASNLSKELC 443

  Fly   373 ALVFGFNTFVGLLLQCILTFVVVSEKANLNLNVFQQFSVYAFYFIVIGIVY---SIAVILQYIWS 434
            |||||.|||...:|:.|:| :::::|..|.|:|..||.||..||.|:.::|   :..||:::..:
 Frog   444 ALVFGVNTFFATILKTIIT-IIIADKRGLALSVHPQFYVYFAYFTVLAVLYLGAAAFVIIRHYHA 507

  Fly   435 --ISKKPKAI 442
              :.:||:.:
 Frog   508 ERLKEKPQVL 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14694	NP_650028.1	Folate_carrier	2..411	CDD:280024	137/427 (32%)
slc19a1	XP_002932056.1	Folate_carrier	75..481	CDD:366800	137/427 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	287	1.000	Domainoid score	I1556
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	287	1.000	Inparanoid score	I2768
OMA	1	1.010	-	-		QHG56145
OrthoDB	1	1.010	-	-		D344994at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9368
Panther	1	1.100	-	-	O	PTHR10686
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X476
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.080