DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4511 and Txndc9

DIOPT Version :9

Sequence 1:	NP_001163585.1	Gene:	CG4511 / 41305	FlyBaseID:	FBgn0037843	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	NP_742051.1	Gene:	Txndc9 / 98258	MGIID:	2138153	Length:	226	Species:	Mus musculus

Alignment Length:	215	Identity:	115/215 - (53%)
Similarity:	153/215 - (71%)	Gaps:	5/215 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ANILENQLFTAAKTIEQQLDQQLDRLDNLDSDDLKVLREQRLREMKDLNNKKQEWLRNGHGTYTE 66
            :.:||||...|||.:|..||.::.:||.:..|:|::|:|:||..::....:|||||..|||.|.|
Mouse    11 SEVLENQFLQAAKLVENHLDSEIQKLDQIGEDELELLKEKRLAALRKAQQQKQEWLSKGHGEYRE 75

  Fly    67 LADEKEFFEMSKKSPNIVCHFYRDSTERCKIVDMHLKILAAKHVEAKFCKVNAEKTPFLTQRLRI 131
            :..|::||:..|:|..:|||||||:|.||||:|.||.|||.||:|.||.|:|.||.|||.:||||
Mouse    76 IGSERDFFQEVKESEKVVCHFYRDTTFRCKILDRHLAILAKKHLETKFLKLNVEKAPFLCERLRI 140

  Fly   132 KVIPTIALVKDSKTKDFIVGFTDLGNCDDFATEMLEWRIAHSGAIDYKGDLMQPPDVKRKP---- 192
            |||||:||::|.||:|::||||||||.|||.||.||||:..|..|:|.|:||:||...:|.
Mouse   141 KVIPTLALLRDGKTQDYVVGFTDLGNTDDFTTETLEWRLGCSDVINYSGNLMEPPFQSQKKFGTN 205

  Fly   193 FINRPQKTIRG-GYDSDDSD 211
            |....:||||| .||||..|
Mouse   206 FTKLEKKTIRGKKYDSDSDD 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4511	NP_001163585.1	crotonase-like	<11..46	CDD:304874	14/34 (41%)
CG4511	NP_001163585.1	Phd_like_TxnDC9	60..171	CDD:239287	72/110 (65%)
Txndc9	NP_742051.1	Phd_like_TxnDC9	68..180	CDD:239287	72/111 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842664
Domainoid	1	1.000	122	1.000	Domainoid score	I5643
eggNOG	1	0.900	-	-		E2759_KOG1672
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4225
Inparanoid	1	1.050	243	1.000	Inparanoid score	I3292
Isobase	1	0.950	-	0	Normalized mean entropy	S1434
OMA	1	1.010	-	-		QHG54224
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002555
OrthoInspector	1	1.000	-	-		oto92004
orthoMCL	1	0.900	-	-		OOG6_101215
Panther	1	1.100	-	-	LDO	PTHR21148
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1508
SonicParanoid	1	1.000	-	-		X2265
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740