DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4511 and PLP1

DIOPT Version :9

Sequence 1:	NP_001163585.1	Gene:	CG4511 / 41305	FlyBaseID:	FBgn0037843	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	NP_010469.3	Gene:	PLP1 / 851764	SGDID:	S000002591	Length:	230	Species:	Saccharomyces cerevisiae

Alignment Length:	226	Identity:	67/226 - (29%)
Similarity:	113/226 - (50%)	Gaps:	20/226 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 NILENQLFTAAKTI--------EQQLDQQLDRLD-NLDSDD--LKVLREQRLREMKD-LNNKKQE 55
            |:|.|.......|:        |:.||:.|:.|| .||.|.  |...|.:||:::.| |...|:.
Yeast    11 NVLSNAEKDKHTTVDSDDKSSGEENLDELLNELDRELDEDHEFLSAYRSERLQQISDHLKQVKKN 75

  Fly    56 WLRNGHGTYTELADEKEFFEMSKKSPNIVCHFYRDSTERCKIVDMHLKILAAKHVEAKFCKVNAE 120
            ...:|:|....:.:|.:..::..|:..:|.||..::..:|:.::..|:.||.:::..:|.|||.:
Yeast    76 VEDDGYGRLQCIDNEADAIQICTKTTMVVIHFELETFGKCQYMNEKLENLAKRYLTTRFIKVNVQ 140

  Fly   121 KTPFLTQRLRIKVIPTIALVKDSKTKDFIVGFTDLGN-CDDFATEMLEWRIAHSGAIDYKGDLMQ 184
            ..|||..:|.|||:|.:...|:...|...|||:.||| .:.|....||..:||||.|:...::.:
Yeast   141 TCPFLVNKLNIKVLPFVVGYKNGLEKVRYVGFSKLGNDPNGFDIRRLEQSLAHSGVIEDTFEIRK 205

  Fly   185 PPDVKRKPFINRPQKTIRGGYDSDDSDIDLD 215
            ...|..:.|.:.       .:|..:||.|||
Yeast   206 HSSVNTERFAST-------NHDRSESDSDLD 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4511	NP_001163585.1	crotonase-like	<11..46	CDD:304874	14/45 (31%)
CG4511	NP_001163585.1	Phd_like_TxnDC9	60..171	CDD:239287	34/111 (31%)
PLP1	NP_010469.3	Phd_like_TxnDC9	80..192	CDD:239287	34/111 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	61	1.000	Domainoid score	I2535
eggNOG	1	0.900	-	-		E2759_KOG1672
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	93	1.000	Inparanoid score	I1519
Isobase	1	0.950	-	0	Normalized mean entropy	S1434
OMA	1	1.010	-	-		QHG54224
OrthoFinder	1	1.000	-	-		FOG0002555
OrthoInspector	1	1.000	-	-		oto98986
orthoMCL	1	0.900	-	-		OOG6_101215
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1508
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.710