DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4511 and txndc9

DIOPT Version :9

Sequence 1:	NP_001163585.1	Gene:	CG4511 / 41305	FlyBaseID:	FBgn0037843	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	NP_001315504.1	Gene:	txndc9 / 336625	ZFINID:	ZDB-GENE-030131-8569	Length:	226	Species:	Danio rerio

Alignment Length:	218	Identity:	123/218 - (56%)
Similarity:	163/218 - (74%)	Gaps:	5/218 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MANILENQLFTAAKTIEQQLDQQLDRLDNLDSDDLKVLREQRLREMKDLNNKKQEWLRNGHGTYT 65
            :|..||.|:..:|:.:|:|||.:|::|:.:|.|:|::|:|:||..:|....:||||:..|||.|.
Zfish     9 VAKALEQQVLQSARMVEEQLDAELEKLERMDEDELELLKERRLEALKKAQKQKQEWISKGHGEYR 73

  Fly    66 ELADEKEFFEMSKKSPNIVCHFYRDSTERCKIVDMHLKILAAKHVEAKFCKVNAEKTPFLTQRLR 130
            |:..||:||...|:|.::|||||||||.||||:|.||.|||.||:|.||.|:|.||.||||:|||
Zfish    74 EIPSEKDFFPEVKESKSVVCHFYRDSTFRCKILDKHLAILAKKHLETKFIKLNVEKAPFLTERLR 138

  Fly   131 IKVIPTIALVKDSKTKDFIVGFTDLGNCDDFATEMLEWRIAHSGAIDYKGDLMQPPDVKRK---P 192
            ||||||:|||||.||||:||||:||||.|:|.|||||||:..|..|:|.|:|::||.|.:|   .
Zfish   139 IKVIPTLALVKDGKTKDYIVGFSDLGNTDEFPTEMLEWRLGCSDIINYSGNLLEPPTVGQKTGSK 203

  Fly   193 FINRPQKTIRG-GYDSD-DSDID 213
            |....:||||| .|||| :||.|
Zfish   204 FTKVEKKTIRGKAYDSDSESDED 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4511	NP_001163585.1	crotonase-like	<11..46	CDD:304874	14/34 (41%)
CG4511	NP_001163585.1	Phd_like_TxnDC9	60..171	CDD:239287	78/110 (71%)
txndc9	NP_001315504.1	RapA_C	<1..58	CDD:288951	19/48 (40%)
txndc9	NP_001315504.1	Phd_like_TxnDC9	67..179	CDD:239287	78/111 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587087
Domainoid	1	1.000	128	1.000	Domainoid score	I5275
eggNOG	1	0.900	-	-		E2759_KOG1672
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4225
Inparanoid	1	1.050	252	1.000	Inparanoid score	I3198
OMA	1	1.010	-	-		QHG54224
OrthoDB	1	1.010	-	-		D1444223at2759
OrthoFinder	1	1.000	-	-		FOG0002555
OrthoInspector	1	1.000	-	-		oto38685
orthoMCL	1	0.900	-	-		OOG6_101215
Panther	1	1.100	-	-	LDO	PTHR21148
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1508
SonicParanoid	1	1.000	-	-		X2265
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800