DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4511 and tgt-2

DIOPT Version :9

Sequence 1:	NP_001163585.1	Gene:	CG4511 / 41305	FlyBaseID:	FBgn0037843	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	NP_741662.1	Gene:	tgt-2 / 180244	WormBaseID:	WBGene00006567	Length:	373	Species:	Caenorhabditis elegans

Alignment Length:	159	Identity:	39/159 - (24%)
Similarity:	64/159 - (40%)	Gaps:	36/159 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 QEWLRNGHGTYT--ELA------DEKEFFEMSKKSPNIVCHFYRDSTERCKIVDMHLKILAAKHV 110
            |.:||.||..:.  |:|      ::...|:|:  .|.:|        ...||::...|      .
Worm    34 QTYLRAGHIPHLTWEVAENQLKLEQTHIFQMT--LPTLV--------SNAKIIEKFGK------G 82

  Fly   111 EAKFCKVNAEKTPFLTQRLRIKVIPTIALVKDSKTKDFIVGFTDLGNCDDFATEMLEWR-IAHS- 173
            .||||.:.|.....||....:..:|  ....|||:   :..:|..|.   .:.::..|| |.:|
Worm    83 AAKFCGMPAGAAVHLTPFDPLGKLP--GGYNDSKS---VAIWTANGK---VSLDVKMWREIINSF 139

  Fly   174 --GAIDYKGDLMQPPDVKRKPFINRPQKT 200
              |:|:...|...|.||.:|..:....:|
Worm   140 GCGSIETLVDYDTPKDVGQKKLVKAVDRT 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4511	NP_001163585.1	crotonase-like	<11..46	CDD:304874
CG4511	NP_001163585.1	Phd_like_TxnDC9	60..171	CDD:239287	26/119 (22%)
tgt-2	NP_741662.1	Tgt	4..369	CDD:223420	39/159 (25%)
tgt-2	NP_741662.1	TGT	149..369	CDD:279966	6/20 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1508
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030