Protein Alignment CG6567 and LYPLA2

DIOPT Version :10

• Sequence 1: NP_001097742.1
• Gene: CG6567 / 41304
• FlyBaseID: FBgn0037842
• Length: 235
• Species: Drosophila melanogaster
• Sequence 2: XP_005245785.1
• Gene: LYPLA2 / 11313
• HGNCID: 6738
• Length: 243
• Species: Homo sapiens
• Alignment Length: 237
• Identity: 80/237 - (33%)
• Similarity: 121/237 - (51%)
• Gaps: 26/237 - (10%)

  Fly     3 PALT---TVNATGKHTASVIFFHGSGDTGPNVLEWVRFLIGRNLEYPHIKIIYPTAPKQKYTPLD 64
            |.||   ||:...:.||:|||.||.||||.:   |...|  ..:..||:|.|.|.||:   .|:.
Human    21 PLLTDAATVSGAERETAAVIFLHGLGDTGHS---WADAL--STIRLPHVKYICPHAPR---IPVT 77

  Fly    65 GELSNV---WFDRKSVNIAASESKKSMSQCYDAVNQLIDEEVASGIPLNRIVVGGFSMGGALALH 126
            ..:..|   |||...::..|.|.:..:.:..:.:..||:.|:.:|||.||||:||||.||||:|:
Human    78 LNMKMVMPSWFDLMGLSPDAPEDEAGIKKAAENIKALIEHEMKNGIPANRIVLGGFSQGGALSLY 142

  Fly   127 TGYHLRRSLAGVFAHSSF--LNRGSVVYDSLANGKDESFPELRMYHGERDTLVPKDWGLETFENL 189
            |.......|||:.|.|.:  |:|   .:...|||..:....|:. |||.|.:||..:|..|.|.|
Human   143 TALTCPHPLAGIVALSCWLPLHR---AFPQAANGSAKDLAILQC-HGELDPMVPVRFGALTAEKL 203

  Fly   190 ----TKLGVKGTFHPLRNTLHELKTASITDLQQWIYEKLPPL 227
                |...|:...:|  ..:|......:..:::::.:.|||:
Human   204 RSVVTPARVQFKTYP--GVMHSSCPQEMAAVKEFLEKLLPPV 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6567	NP_001097742.1	alpha/beta hydrolases	7..221	CDD:473884	74/222 (33%)
LYPLA2	XP_005245785.1	Abhydrolase_2	23..240	CDD:396693	76/230 (33%)