Protein Alignment CG6567 and LYPLA1

DIOPT Version :10

• Sequence 1: NP_001097742.1
• Gene: CG6567 / 41304
• FlyBaseID: FBgn0037842
• Length: 235
• Species: Drosophila melanogaster
• Sequence 2: NP_006321.1
• Gene: LYPLA1 / 10434
• HGNCID: 6737
• Length: 230
• Species: Homo sapiens
• Alignment Length: 239
• Identity: 82/239 - (34%)
• Similarity: 115/239 - (48%)
• Gaps: 32/239 - (13%)

  Fly     3 PALTTVNATGKHTASVIFFHGSGDTGPNVLEWVRFLIGRNLEYPHIKIIYPTAPKQKYTPLDGEL 67
            ||:  |.|..|.||:|||.||.||||..   |.....|  :...|||.|.|.||.:..|......
Human    11 PAI--VPAARKATAAVIFLHGLGDTGHG---WAEAFAG--IRSSHIKYICPHAPVRPVTLNMNVA 68

  Fly    68 SNVWFDRKSVNIAASESKKSMSQCYDAVNQLIDEEVASGIPLNRIVVGGFSMGGALALHTGYHLR 132
            ...|||...::..:.|.:..:.|..:.:..|||:||.:|||.|||::||||.||||:|:|....:
Human    69 MPSWFDIIGLSPDSQEDESGIKQAAENIKALIDQEVKNGIPSNRIILGGFSQGGALSLYTALTTQ 133

  Fly   133 RSLAGVFAHSSFLNRGSVVYDSLANGKDESFPE-----------LRMYHGERDTLVPKDWGLETF 186
            :.||||.|.|.:|...:            |||:           :...||:.|.|||..:|..|.
Human   134 QKLAGVTALSCWLPLRA------------SFPQGPIGGANRDISILQCHGDCDPLVPLMFGSLTV 186

  Fly   187 ENLTKL--GVKGTFHPLRNTLHELKTASITDLQQWIYEKLPPLE 228
            |.|..|  ....||......:|......:.|::|:|.:.|||::
Human   187 EKLKTLVNPANVTFKTYEGMMHSSCQQEMMDVKQFIDKLLPPID 230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6567	NP_001097742.1	alpha/beta hydrolases	7..221	CDD:473884	76/226 (34%)
LYPLA1	NP_006321.1	Abhydrolase_2	11..226	CDD:396693	79/233 (34%)