Protein Alignment CG4565 and NSD2

DIOPT Version :10

• Sequence 1: NP_001097743.1
• Gene: CG4565 / 41303
• FlyBaseID: FBgn0037841
• Length: 269
• Species: Drosophila melanogaster
• Sequence 2: NP_001427822.1
• Gene: NSD2 / 7468
• HGNCID: 12766
• Length: 1398
• Species: Homo sapiens
• Alignment Length: 234
• Identity: 74/234 - (31%)
• Similarity: 107/234 - (45%)
• Gaps: 59/234 - (25%)

  Fly    50 CHCKGACENSEVCAHGGQYEFTEDGSELILRNSANPVIECN-DMC---KCCRNTCSNRLVYSGPR 110
            |:||...||.  |..         .||.:.|..   :.||: .:|   :.|:|.|..:..|  |.
Human  1049 CNCKPTDENP--CGF---------DSECLNRML---MFECHPQVCPAGEFCQNQCFTKRQY--PE 1097

  Fly   111 KHLEIFDSPVYGSKGLRTTAK--ITKGGYICEYAGELLTVPEARSRL---HDNEKLGLMNYILVL 170
            ..:...|     .||....||  |.||.::.||.|||:...|..:|:   |:|:    :.:..:|
Human  1098 TKIIKTD-----GKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHEND----ITHFYML 1153

  Fly   171 NEYTSDKKQQVTIVDPSRRGNIGRYLNHSCEPNCHIAAVRIDCPIPKIGIFAARDIAAKEELCFH 235
               |.||.:   |:|...:||..|::||||:|||......::.. .::|:||..||.|..||.|:
Human  1154 ---TIDKDR---IIDAGPKGNYSRFMNHSCQPNCETLKWTVNGD-TRVGLFAVCDIPAGTELTFN 1211

  Fly   236 Y-----GGEGQYKKMTGGKT-CLCGASKCTGFM---PNT 265
            |     |.|         || |.||||.|:||:   |.|
Human  1212 YNLDCLGNE---------KTVCRCGASNCSGFLGDRPKT 1241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4565	NP_001097743.1	SET_SETMAR	16..267	CDD:380942	74/234 (32%)
NSD2	NP_001427822.1	None