Protein Alignment CG4565 and SETMAR

DIOPT Version :10

• Sequence 1: NP_001097743.1
• Gene: CG4565 / 41303
• FlyBaseID: FBgn0037841
• Length: 269
• Species: Drosophila melanogaster
• Sequence 2: NP_006506.3
• Gene: SETMAR / 6419
• HGNCID: 10762
• Length: 684
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 101/295 - (34%)
• Similarity: 141/295 - (47%)
• Gaps: 48/295 - (16%)

  Fly     3 ESETAPNDDYEHPDGLDYILESVLMPSDGSKEFKFLAD---------EYNSVLLNPCHC------ 52
            |...||.:..:...|.:.:......|......|::..|         :...:....|.|
Human    19 EKPEAPTEQLDVACGQENLPVGAWPPGAAPAPFQYTPDHVVGPGADIDPTQITFPGCICVKTPCL 83

  Fly    53 KGACENSEVC-AHGGQYEFTEDGSELILRN------SANPVIECNDMCKCCRNTCSNRLVYSGPR 110
            .|.|.    | .||..|   :|.|  .||:      .|.||.|||.:|: |.:.|.||:|..|.:
Human    84 PGTCS----CLRHGENY---DDNS--CLRDIGSGGKYAEPVFECNVLCR-CSDHCRNRVVQKGLQ 138

  Fly   111 KHLEIFDSPVYGSKGLRTTAKITKGGYICEYAGELLTVPEARSRLHDNEKLGLMNYILVLNEYTS 175
            .|.::|.:...| .||||...|.||.::||||||:|...|.:.|:|...|.. .|||:.:.|:..
Human   139 FHFQVFKTHKKG-WGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHLQTKSD-SNYIIAIREHVY 201

  Fly   176 DKKQQVTIVDPSRRGNIGRYLNHSCEPNCHIAAVRIDCPIPKIGIFAARDIAAKEELCFHYGGEG 240
            :.:...|.|||:..|||||:||||||||..:..||||..:||:.:|||:||..:|||.:.|  .|
Human   202 NGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSMVPKLALFAAKDIVPEEELSYDY--SG 264

  Fly   241 QYKKMTGG------------KTCLCGASKCTGFMP 263
            :|..:|..            |.|.|||..||.|:|
Human   265 RYLNLTVSEDKERLDHGKLRKPCYCGAKSCTAFLP 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4565	NP_001097743.1	SET_SETMAR	16..267	CDD:380942	98/282 (35%)
SETMAR	NP_006506.3	Histone-lysine N-methyltransferase	1..345		101/295 (34%)
		SET_SETMAR	51..303	CDD:380942	96/263 (37%)
		Mariner transposase Hsmar1	346..684
		HTH_48	348..397	CDD:465558
		transpos_IS630	383..655	CDD:468076
		Transposase_1	501..580	CDD:460174