Protein Alignment CG4565 and E(z)

DIOPT Version :10

• Sequence 1: NP_001097743.1
• Gene: CG4565 / 41303
• FlyBaseID: FBgn0037841
• Length: 269
• Species: Drosophila melanogaster
• Sequence 2: NP_001261682.1
• Gene: E(z) / 39203
• FlyBaseID: FBgn0000629
• Length: 765
• Species: Drosophila melanogaster
• Alignment Length: 210
• Identity: 66/210 - (31%)
• Similarity: 96/210 - (45%)
• Gaps: 44/210 - (20%)

  Fly    50 CHCKGACENSEVCAHGGQYEFTEDGSELILRNSANPVIECN-DMCKCC--------RNTCSNRLV 105
            |.||..| |::.|.           ..|.:|       ||: |:|:.|        :.||.|..|
  Fly   580 CRCKAQC-NTKQCP-----------CYLAVR-------ECDPDLCQACGADQFKLTKITCKNVCV 625

  Fly   106 YSGPRKHLEIFDSPVYGSKGLRTTAKITKGGYICEYAGELLTVPEA--RSRLHDNEKLGLMNYIL 168
            ..|..|||.:..|.:.| .|:.......|..:|.||.||:::..||  |.:::|..   :.:::.
  Fly   626 QRGLHKHLLMAPSDIAG-WGIFLKEGAQKNEFISEYCGEIISQDEADRRGKVYDKY---MCSFLF 686

  Fly   169 VLNEYTSDKKQQVTIVDPSRRGNIGRYLNHSCEPNCHIAAVRIDCPIPKIGIFAARDIAAKEELC 233
            .||   :|     .:||.:|:||..|:.|||..|||: |.|.:.....:|||||.|.|...|||.
  Fly   687 NLN---ND-----FVVDATRKGNKIRFANHSINPNCY-AKVMMVTGDHRIGIFAKRAIQPGEELF 742

  Fly   234 FHYG-GEGQYKKMTG 247
            |.|. |..:..|..|
  Fly   743 FDYRYGPTEQLKFVG 757

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4565	NP_001097743.1	SET_SETMAR	16..267	CDD:380942	66/210 (31%)
E(z)	NP_001261682.1	PRC2_HTH_1	151..291	CDD:436286
		SANT	452..492	CDD:238096
		preSET_CXC	579..610	CDD:408079	13/48 (27%)
		SET_EZH2	628..747	CDD:380995	46/131 (35%)