Protein Alignment CG4565 and Nsd1

DIOPT Version :10

• Sequence 1: NP_001097743.1
• Gene: CG4565 / 41303
• FlyBaseID: FBgn0037841
• Length: 269
• Species: Drosophila melanogaster
• Sequence 2: NP_001388465.1
• Gene: Nsd1 / 306764
• RGDID: 1307748
• Length: 2689
• Species: Rattus norvegicus
• Alignment Length: 253
• Identity: 74/253 - (29%)
• Similarity: 110/253 - (43%)
• Gaps: 76/253 - (30%)

  Fly    13 EHPDGLDYILESVLMPSDGSKEFKFLADEYNSVLLNPCHCKGACENSEVCAHGGQYEFTEDGSEL 77
            |:|.|:|                   ::..|.:||..||       ..||..||:
  Rat  1900 ENPCGID-------------------SECINRMLLYECH-------PTVCPAGGR---------- 1928

  Fly    78 ILRNSANPVIECNDMCKCCRNTCSNRLVYSGPRKHLEIFDSPVYGSKGLRTTAKITKGGYICEYA 142
                              |:|.|.::..|    ..:|||.:...| .||||...|.||.::.||.
  Rat  1929 ------------------CQNQCFSKRQY----PDVEIFRTLQRG-WGLRTKTDIKKGEFVNEYV 1970

  Fly   143 GELLTVPEARSRLHDNEKLGLMNYILVLNEYTSDKKQQVTIVDPSRRGNIGRYLNHSCEPNCHIA 207
            |||:...|.|:|:...::..:.|:.::    |.||.:   |:|...:||..|::||.|:|||...
  Rat  1971 GELIDEEECRARIRYAQEHDITNFYML----TLDKDR---IIDAGPKGNYARFMNHCCQPNCETQ 2028

  Fly   208 --AVRIDCPIPKIGIFAARDIAAKEELCFHYGGEGQYKKMTGGKT-CLCGASKCTGFM 262
              :|..|   .::|:||..||.|..||.|:|..|    .:..||| |.|||..|:||:
  Rat  2029 KWSVNGD---TRVGLFALSDIKAGTELTFNYNLE----CLGNGKTVCKCGAPNCSGFL 2079

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4565	NP_001097743.1	SET_SETMAR	16..267	CDD:380942	72/250 (29%)
Nsd1	NP_001388465.1	PWWP_NSD1_rpt1	318..433	CDD:438989
		TNG2	<1452..1585	CDD:227367
		PHD1_NSD1_2	1543..1585	CDD:277118
		PHD2_NSD1	1590..1636	CDD:277120
		PHD3_NSD1	1637..1690	CDD:277123
		PHD4_NSD1	1707..1746	CDD:277126
		PWWP_NSD1_rpt2	1753..1848	CDD:438992
		AWS	1899..1937	CDD:465559	16/90 (18%)
		SET_NSD1	1939..2080	CDD:380987	58/160 (36%)
		PHD5_NSD1	2118..2160	CDD:277129
		C5HCH	2159..2208	CDD:465605
		PHA03247	<2221..2593	CDD:223021