Protein Alignment CG4565 and Ezh1

DIOPT Version :10

• Sequence 1: NP_001097743.1
• Gene: CG4565 / 41303
• FlyBaseID: FBgn0037841
• Length: 269
• Species: Drosophila melanogaster
• Sequence 2: NP_001100521.1
• Gene: Ezh1 / 303547
• RGDID: 1305028
• Length: 747
• Species: Rattus norvegicus
• Alignment Length: 199
• Identity: 63/199 - (31%)
• Similarity: 92/199 - (46%)
• Gaps: 44/199 - (22%)

  Fly    50 CHCKGACENSEVCAHGGQYEFTEDGSELILRNSANPVIECN-DMCKCCRN---------TCSNRL 104
            |.||..| |::.|.           ..|.:|       ||: |:|..|..         :|.|..
  Rat   561 CRCKTQC-NTKQCP-----------CYLAVR-------ECDPDLCLTCGASEHWDCKVVSCKNCS 606

  Fly   105 VYSGPRKHLEIFDSPVYGSKGLRTTAKITKGGYICEYAGELLTVPEA--RSRLHDNEKLGLMNYI 167
            :..|.:|||.:..|.|.| .|......:.|..:|.||.|||::..||  |.:::|..   :.:::
  Rat   607 IQRGLKKHLLLAPSDVAG-WGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKY---MSSFL 667

  Fly   168 LVLNEYTSDKKQQVTIVDPSRRGNIGRYLNHSCEPNCHIAAVRIDCPIPKIGIFAARDIAAKEEL 232
            ..||   :|     .:||.:|:||..|:.|||..|||:...|.::.. .:|||||.|.|.|.|||
  Rat   668 FNLN---ND-----FVVDATRKGNKIRFANHSVNPNCYAKVVMVNGD-HRIGIFAKRAIQAGEEL 723

  Fly   233 CFHY 236
            .|.|
  Rat   724 FFDY 727

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4565	NP_001097743.1	SET_SETMAR	16..267	CDD:380942	63/199 (32%)
Ezh1	NP_001100521.1	EZH2_WD-Binding	39..68	CDD:463308
		PRC2_HTH_1	159..262	CDD:436286
		SANT	433..474	CDD:238096
		preSET_CXC	560..591	CDD:408079	13/48 (27%)
		SET_EZH1	608..743	CDD:380994	48/133 (36%)