Protein Alignment CG4565 and Nsd3

DIOPT Version :10

• Sequence 1: NP_001097743.1
• Gene: CG4565 / 41303
• FlyBaseID: FBgn0037841
• Length: 269
• Species: Drosophila melanogaster
• Sequence 2: XP_038950324.1
• Gene: Nsd3 / 290831
• RGDID: 1308980
• Length: 1444
• Species: Rattus norvegicus
• Alignment Length: 229
• Identity: 71/229 - (31%)
• Similarity: 100/229 - (43%)
• Gaps: 58/229 - (25%)

  Fly    50 CHCKGACEN-----SEVCAHGGQYEFTEDGSELILRNSANPVIECN-DMCKC---CRNTCSNRLV 105
            |:||...||     ||......||                   ||: .:|..   |:|.|..:.:
  Rat  1106 CNCKPGDENPCGLESECLNRMSQY-------------------ECHPQVCPAGDRCQNQCFTKRL 1151

  Fly   106 YSGPRKHLEIFDSPVYGSKGLRTTAKITKGGYICEYAGELLTVPEARSRL---HDNEKLGLMNYI 167
            |    ...||..:...| .||||...|.||.::.||.|||:...|.|.|:   |:|.....  |:
  Rat  1152 Y----PDAEIIKTERRG-WGLRTKRSIKKGEFVNEYVGELIDEEECRLRIKRAHENSVTNF--YM 1209

  Fly   168 LVLNEYTSDKKQQVTIVDPSRRGNIGRYLNHSCEPNCHIAAVRIDCPIPKIGIFAARDIAAKEEL 232
            |.:   |.|:     |:|...:||..|::||||.|||......::..: ::|:||..||.|..||
  Rat  1210 LTV---TKDR-----IIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDV-RVGLFALCDIPAGMEL 1265

  Fly   233 CFHYG----GEGQYKKMTGGKTCLCGASKCTGFM 262
            .|:|.    |.|:       ..|.|||..|:||:
  Rat  1266 TFNYNLDCLGNGR-------TVCHCGADNCSGFL 1292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4565	NP_001097743.1	SET_SETMAR	16..267	CDD:380942	71/229 (31%)
Nsd3	XP_038950324.1	PWWP_NSD3_rpt1	275..404	CDD:438991
		PHD1_NSD3	711..753	CDD:277119
		PHD2_NSD3	759..805	CDD:277122
		PHD_SF	806..858	CDD:473978
		PHD4_NSD3	925..960	CDD:277128
		PWWP_NSD3_rpt2	967..1061	CDD:438994
		AWS	1112..1150	CDD:465559	12/56 (21%)
		SET_NSD3	1152..1293	CDD:380989	56/164 (34%)
		PHD5_NSD3	1330..1372	CDD:277131
		C5HCH	1371..1420	CDD:465605