Protein Alignment CG4565 and mes-2

DIOPT Version :10

• Sequence 1: NP_001097743.1
• Gene: CG4565 / 41303
• FlyBaseID: FBgn0037841
• Length: 269
• Species: Drosophila melanogaster
• Sequence 2: NP_496992.3
• Gene: mes-2 / 175096
• WormBaseID: WBGene00003220
• Length: 773
• Species: Caenorhabditis elegans
• Alignment Length: 274
• Identity: 68/274 - (24%)
• Similarity: 103/274 - (37%)
• Gaps: 73/274 - (26%)

  Fly    16 DGLDYILESVLMPSDGSKEFKFLADEYNSVLLNP---CHCKG---------ACENSEVCAH---- 64
            ||||   ...|:..|..::.:..:::.....:.|   |...|         ||..:.||::
 Worm   497 DGLD---AEKLIREDDMRDSQRNSEKVRMTAVTPITACRHAGPCNATAENCACRENGVCSYMCKC 558

  Fly    65 --------------GGQYEFTEDGSELILRNSANPVIECNDMCKC---------CRNTCSNRLV- 105
                          .||. :|:...........|| :.|| ||||         |||....|::
 Worm   559 DINCSQRFPGCNCAAGQC-YTKACQCYRANWECNP-MTCN-MCKCDAIDSNIIKCRNFGMTRMIQ 620

  Fly   106 ---YSGPRKHLEIFDSPVYGSKGLRTTAKITKGGYICEYAGELLTVPEA--RSRLHDNEKLGLMN 165
               |.||.|         ....||.......|..:|.||.||.::..||  |..::|..:   .:
 Worm   621 KRTYCGPSK---------IAGNGLFLLEPAEKDEFITEYTGERISDDEAERRGAIYDRYQ---CS 673

  Fly   166 YILVLNEYTSDKKQQVTIVDPSRRGNIGRYLNH-SCEPNCHIAAVRIDCPIPKIGIFAARDIAAK 229
            ||  .|..|..      .:|..:.||:.|:.|| |..|.|: |...:.....:||.:|.|.:...
 Worm   674 YI--FNIETGG------AIDSYKIGNLARFANHDSKNPTCY-ARTMVVAGEHRIGFYAKRRLEIS 729

  Fly   230 EELCFHYGGEGQYK 243
            |||.|.|...|:::
 Worm   730 EELTFDYSYSGEHQ 743

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4565	NP_001097743.1	SET_SETMAR	16..267	CDD:380942	68/274 (25%)
mes-2	NP_496992.3	Septum_form	<210..266	CDD:433522
		preSET_CXC	568..600	CDD:408079	9/34 (26%)
		SET_EZH	621..738	CDD:380917	39/137 (28%)