Protein Alignment CG4565 and Ehmt2

DIOPT Version :10

• Sequence 1: NP_001097743.1
• Gene: CG4565 / 41303
• FlyBaseID: FBgn0037841
• Length: 269
• Species: Drosophila melanogaster
• Sequence 2: NP_001390796.1
• Gene: Ehmt2 / 110147
• MGIID: 2148922
• Length: 1394
• Species: Mus musculus
• Alignment Length: 269
• Identity: 86/269 - (31%)
• Similarity: 129/269 - (47%)
• Gaps: 57/269 - (21%)

  Fly    23 ESVLMPS----DGS---KEFKFLAD---------EYNSVLLNPCHCKGACENSE-VCAHGGQYE- 69
            |:|.:|.    ||.   :::|::::         :.|...|..|.|...|.:|. :|   ||..
Mouse  1115 ENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDDCSSSNCLC---GQLSI 1176

  Fly    70 ---FTEDGSELILRNSANP--VIECNDMCKCCRNTCSNRLVYSGPRKHLEIFDSPVYGSKGLRTT 129
               :.:||..|...|...|  :.|||..|.|.| :|.||:|.||.:..|:::.:...| .|:|..
Mouse  1177 RCWYDKDGRLLQEFNKIEPPLIFECNQACSCWR-SCKNRVVQSGIKVRLQLYRTAKMG-WGVRAL 1239

  Fly   130 AKITKGGYICEYAGELLTVPEARSRLHDNEKLGLMNYILVLNEYTSDKKQQVTIVDPSRRGNIGR 194
            ..|.:|.:||||.|||::..||..|..|       :|:..|:    :|..:|..:|....|||.|
Mouse  1240 QTIPQGTFICEYVGELISDAEADVREDD-------SYLFDLD----NKDGEVYCIDARYYGNISR 1293

  Fly   195 YLNHSCEPNCHIAAVRI-----DCPIPKIGIFAARDIAAKEELCFHYGG-----EGQYKKMTGGK 249
            ::||.|:||  |..||:     |...|:|..|::|||...|||.|.||.     :.:|      .
Mouse  1294 FINHLCDPN--IIPVRVFMLHQDLRFPRIAFFSSRDIRTGEELGFDYGDRFWDIKSKY------F 1350

  Fly   250 TCLCGASKC 258
            ||.||:.||
Mouse  1351 TCQCGSEKC 1359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4565	NP_001097743.1	SET_SETMAR	16..267	CDD:380942	86/269 (32%)
Ehmt2	NP_001390796.1	PHA03247	<126..379	CDD:223021
		EHMT_ZBD	594..723	CDD:411018
		ANKYR	838..1071	CDD:440430
		ANK repeat	870..899	CDD:293786
		ANK repeat	934..966	CDD:293786
		ANK repeat	969..999	CDD:293786
		ANK repeat	1001..1032	CDD:293786
		ANK repeat	1034..1065	CDD:293786
		SET_EHMT2	1132..1370	CDD:380931	81/252 (32%)