Protein Alignment CG4565 and EHMT2

DIOPT Version :10

• Sequence 1: NP_001097743.1
• Gene: CG4565 / 41303
• FlyBaseID: FBgn0037841
• Length: 269
• Species: Drosophila melanogaster
• Sequence 2: XP_006715037.2
• Gene: EHMT2 / 10919
• HGNCID: 14129
• Length: 1395
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 87/269 - (32%)
• Similarity: 129/269 - (47%)
• Gaps: 57/269 - (21%)

  Fly    23 ESVLMPS----DGS---KEFKFLAD---------EYNSVLLNPCHCKGACENSE-VCAHGGQYE- 69
            |:|.:|.    ||.   :::|::::         :.|...|..|.|...|.:|. :|   ||..
Human  1116 ENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDDCSSSNCLC---GQLSI 1177

  Fly    70 ---FTEDGSELILRNSANP--VIECNDMCKCCRNTCSNRLVYSGPRKHLEIFDSPVYGSKGLRTT 129
               :.:||..|...|...|  :.|||..|.|.|| |.||:|.||.:..|:::.:...| .|:|..
Human  1178 RCWYDKDGRLLQEFNKIEPPLIFECNQACSCWRN-CKNRVVQSGIKVRLQLYRTAKMG-WGVRAL 1240

  Fly   130 AKITKGGYICEYAGELLTVPEARSRLHDNEKLGLMNYILVLNEYTSDKKQQVTIVDPSRRGNIGR 194
            ..|.:|.:||||.|||::..||..|..|       :|:..|:    :|..:|..:|....|||.|
Human  1241 QTIPQGTFICEYVGELISDAEADVREDD-------SYLFDLD----NKDGEVYCIDARYYGNISR 1294

  Fly   195 YLNHSCEPNCHIAAVRI-----DCPIPKIGIFAARDIAAKEELCFHYGG-----EGQYKKMTGGK 249
            ::||.|:||  |..||:     |...|:|..|::|||...|||.|.||.     :.:|      .
Human  1295 FINHLCDPN--IIPVRVFMLHQDLRFPRIAFFSSRDIRTGEELGFDYGDRFWDIKSKY------F 1351

  Fly   250 TCLCGASKC 258
            ||.||:.||
Human  1352 TCQCGSEKC 1360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4565	NP_001097743.1	SET_SETMAR	16..267	CDD:380942	87/269 (32%)
EHMT2	XP_006715037.2	PHA03247	<126..382	CDD:223021
		2A1904	<396..504	CDD:273344
		EHMT_ZBD	598..727	CDD:411018
		ANKYR	806..1072	CDD:440430
		ANK repeat	864..893	CDD:293786
		ANK repeat	928..960	CDD:293786
		ANK repeat	962..993	CDD:293786
		ANK repeat	1002..1033	CDD:293786
		ANK repeat	1035..1066	CDD:293786
		SET_EHMT2	1133..1371	CDD:380931	82/252 (33%)