Protein Alignment Cad86C and Pcdhb14

DIOPT Version :9

• Sequence 1: NP_001247033.1
• Gene: Cad86C / 41302
• FlyBaseID: FBgn0261053
• Length: 1949
• Species: Drosophila melanogaster
• Sequence 2: NP_444369.3
• Gene: Pcdhb14 / 93885
• MGIID: 2136749
• Length: 796
• Species: Mus musculus
• Alignment Length: 530
• Identity: 122/530 - (23%)
• Similarity: 209/530 - (39%)
• Gaps: 97/530 - (18%)

  Fly   319 LDFEKQAMYHLTILANDAYAEPGQDSRNIAGMEIVVIVQDVQDQPPVFTSAPPVTKLPPGILPGD 383
            ||.|:||...||:.|.|:.:.|     .....::|::|.|:.|..|.|.......::......|.
Mouse   200 LDREEQAQIRLTLTAMDSGSPP-----KTGTTQVVIVVLDINDNAPEFAQGLYEVQVQENSPVGS 259

  Fly   384 KILQVHAEDGDKGNPREVRYGLVSENNPFTSFFDINETSGEIFLMRPLEDIAFITHVGDPVLLTV 448
            .:|.|.|.|.|.|...|:.|.|...:|.....|::|..:||| .:|.|.|.
Mouse   260 LVLTVSARDLDAGTHGELSYSLFQSSNQVLQAFEVNTDTGEI-RVRKLLDF-------------- 309

  Fly   449 IAEEVKVGRDEPPA-----LASTVQLAFFLPDRTNSPPYFENDHYVSRVDENAPHGTALTFVDPY 508
              ||::..|.|..|     |:....:...:.|..::.|.......:|.:.||:|......|
Mouse   310 --EEIQSYRMEIEASDGGGLSGKCTVVIHVMDVNDNAPELTMSVLISEIPENSPETIVAIF---- 368

  Fly   509 VPRVYDDDTGKNGVFSLTLLNNNGTFEISPN-------VAERSAGFLIRVRDNSMLDYEQQQSVQ 566
              .:.|.|:|.||.. :..:.:...|.:.||       |.||:            ||.|.:....
Mouse   369 --GISDPDSGDNGKM-VCSVQDRLPFLLKPNEENFYTLVTERA------------LDRESRAEYN 418

  Fly   567 FQILAQELGPATNLSALVNVTVYINDVNDNAPVFEQPAYSVELPENMTAGTKVVQVLATDPDSGL 631
            ..|...::| ...|:....:||.::|:|||||.|...:|::.:.||.:....:..:.|||.|||.
Mouse   419 ITITVSDMG-TPRLTTQHTITVQVSDINDNAPAFTHTSYTMFVRENNSPALHIGTISATDSDSGS 482

  Fly   632 GGKVRYTAILGY-----LNTSLNLDAETGLITVSTNKHGFDREVMPEYHLYVEARDMDGEGNRAQ 691
            ...:.|:.:..:     ||:.::::|:.|.:..   ....|.|.:..:..:|.|.|.......:|
Mouse   483 NAHITYSLLPPHDPQLALNSLISINADNGQLFA---LRALDYEALQAFEFHVGATDGGSPALSSQ 544

  Fly   692 VPLIIKLIDVNDETPIFDKDLY----------EFILTHDLMGFTTTAVIHAEDKDATAPNNEVRY 746
            ..:.:.::|.||..|..   ||          |.:......|:..|.|: |.|:| :..|..:.:
Mouse   545 ALVRVVVLDDNDNAPFV---LYPMQNASAPCTELLPRAAEPGYLVTKVV-AVDRD-SGQNAWLSF 604

  Fly   747 EIINGNYDNQFVLDKVTGEL-TVREKIHLRSKKNAKTRRRRQAGSDDEDTDIFILTARAYDLGVP 810
            :::.......|.:....||: |.|    |.|:::....|               |.....|.|.|
Mouse   605 QLLKTTEPGLFSVWAHNGEVRTTR----LLSERDVPKHR---------------LLLLVKDNGEP 650

  Fly   811 VRFSTTTIRV 820
            ...::.|:.|
Mouse   651 PHSASVTLHV 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad86C	NP_001247033.1	Cadherin_repeat	260..361	CDD:206637	13/41 (32%)
		Cadherin_repeat	372..469	CDD:206637	25/101 (25%)
		Cadherin_repeat	487..596	CDD:206637	26/115 (23%)
		Cadherin_repeat	605..703	CDD:206637	21/102 (21%)
		Cadherin_repeat	728..820	CDD:206637	18/92 (20%)
Pcdhb14	NP_444369.3	Cadherin_2	30..111	CDD:285466
		Cadherin_repeat	140..238	CDD:206637	13/42 (31%)
		Cadherin_repeat	247..343	CDD:206637	26/112 (23%)
		CA	371..449	CDD:214520	23/91 (25%)
		Cadherin_repeat	455..557	CDD:206637	22/104 (21%)
		Cadherin_repeat	576..664	CDD:206637	21/106 (20%)
		Cadherin_C_2	686..768	CDD:293101

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X20
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000