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Protein Alignment Cad86C and PCDHB7

DIOPT Version :9

Sequence 1:	NP_001247033.1	Gene:	Cad86C / 41302	FlyBaseID:	FBgn0261053	Length:	1949	Species:	Drosophila melanogaster
Sequence 2:	NP_061763.1	Gene:	PCDHB7 / 56129	HGNCID:	8692	Length:	793	Species:	Homo sapiens

Alignment Length:	750	Identity:	173/750 - (23%)
Similarity:	271/750 - (36%)	Gaps:	215/750 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   215 EPGRYYDFQVSVKDTKGGMTTQLCS----------ITATNFTTPHD---LIFPHKPGIIMIPEDA 266
            ||.||:   |:.:..:|...|.|..          ...|...:..:   |:.....|.:::.|..
Human    29 EPLRYF---VAEETERGTFLTNLAKDLGLGVGELRARGTRIVSDQNMQILLLSSLTGDLLLNEKL 90

  Fly   267 KRGTELDYVIARKNP-------LFQKPVYL---ELW------GSPLFAIRQ---KIVSSETTEGT 312
            .|    :.:...:.|       |.:||..:   |||      .:|:|..|:   ||:.| ||.|.
Human    91 DR----EELCGPREPCVLPFQLLLEKPFQIFRAELWVRDINDHAPVFLDREISLKILES-TTPGA 150

  Fly   313 VFLL------------------GP-------------------------LDFEKQAMYHLTILAN 334
            .|||                  .|                         ||.|:...:.||:.|.
Human   151 AFLLESAQDSDVGTNSLSNYTISPNAYFHINVHDSGEGNIYPELVLNQVLDREEIPEFSLTLTAL 215

  Fly   335 DAYAEPGQDSRNIAGMEIV-VIVQDVQDQPPVFTSAPPVTKLPPGILPGDKILQVHAEDGDKGNP 398
            |..:.|.      :|..:| ::|.||.|..|.|..:....::|.....|..::.|.|.|.|.|:.
Human   216 DGGSPPR------SGTALVRILVLDVNDNAPDFVRSLYKVQVPENSPVGSMVVSVSARDLDTGSN 274

  Fly   399 REVRYGLVSENNPFTSFFDINETSGEIFLMRPLEDIAFITHV---------GDPVLLTVIAEEVK 454
            .|:.|............|.||.|||.:.|...|:..|..|:.         |.....||:.:...
Human   275 GEIAYAFSYATERILKTFQINPTSGSLHLKAQLDYEAIQTYTLTIQAKDGGGLSGKCTVVVDVTD 339

  Fly   455 VGRDEPPALASTVQLAFFLPDRTNSPPYFENDHYVSRVDENAPHGTALTFVDPYVPRVYDDDTGK 519
            :..:.|..|.|::                     .|.:.||:|......|      |:.|.|:|.
Human   340 INDNRPELLLSSL---------------------TSPIAENSPETVVAVF------RIRDRDSGN 377

  Fly   520 NGVFSLTLLNNNGTFEISPNVAERSAGFLIRVRDNSMLDYEQQQSVQFQILAQELGPATNLSALV 584
            ||. ::..:.::..|.:.|:|    ..|...|.:.. ||.|:.......|...:|| ...|....
Human   378 NGK-TVCSIQDDVPFILKPSV----ENFYTLVTEKP-LDRERNTEYNITITVTDLG-TPRLKTEH 435

  Fly   585 NVTVYINDVNDNAPVFEQPAYSVELPENMTAGTKVVQVLATDPDSGLGGKVRYTAI--------L 641
            |:||.::|||||||.|.|.:|::.:.||.:....:..|.|||.|||...:|.|:.:        |
Human   436 NITVLVSDVNDNAPAFTQTSYTLFVRENNSPALPIGSVSATDRDSGTNAQVIYSLLPSQDPHLPL 500

  Fly   642 GYLNTSLNLDAETGLITVSTNKHGF-----DREVMPEYHLYVEARDMDGEGNRAQVPLIIKLIDV 701
            ..| .|:|.|          |.|.|     |.|.:..:...|.|.|.......::..:.:.::|.
Human   501 ASL-VSINAD----------NGHLFALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDA 554

  Fly   702 NDETPIFDKDLYEFIL----------THDL-----MGFTTTAVIHAEDKDATAPNNEVRYEIING 751
            ||.:|        |:|          |..|     .|:..|.|: |.|.| :..|..:.|:::..
Human   555 NDNSP--------FVLYPLQNSSAPCTEPLPRAAEPGYLVTKVV-AVDGD-SGQNAWLSYQLLKA 609

  Fly   752 NYDNQFVLDKVTGEL-TVREKIHLRSKKNAKTRRRRQAGSDDEDTDIFILTARAYDLGVPVRFST 815
            .....|.:....||: |.|    |.|:::|..:|               |.....|.|.|.|.:|
Human   610 TEPGLFGVWAHNGEVRTAR----LLSERDAAKQR---------------LVVLVKDNGEPPRSAT 655

  Fly   816 TTIRVY------PPESRKRSVKFVVPGHNPDKAKT 844
            .|:.|.      .|..|       :|...||:|.:
Human   656 ATLHVLLVDGFSQPYLR-------LPEAAPDQANS 683

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.