DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cad86C and AgaP_AGAP006256

DIOPT Version :9

Sequence 1:NP_001247033.1 Gene:Cad86C / 41302 FlyBaseID:FBgn0261053 Length:1949 Species:Drosophila melanogaster
Sequence 2:XP_316322.4 Gene:AgaP_AGAP006256 / 1276914 VectorBaseID:AGAP006256 Length:1821 Species:Anopheles gambiae


Alignment Length:2010 Identity:423/2010 - (21%)
Similarity:685/2010 - (34%) Gaps:618/2010 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   119 RLLTISLLIGIL----C---------PHHVQGADPKFDPTTRMRLVLVPADAQVNSVIYRLRATD 170
            |:..:|||:.::    |         ||.:.|:    ....|..|:   .:..|.||:|:||..|
Mosquito     5 RVKLVSLLVLVVLLQQCARAQIINRTPHFIPGS----GDMARFSLL---ENTPVGSVVYQLRGVD 62

  Fly   171 EEFDYPLTFEFVG-----DASASTVKV-ESLPCTKYNSV-------------CQANIVLQRRLEP 216
            .| ...|.|...|     |..:..|:: :||...:.::|             .:.|.|..||..|
Mosquito    63 PE-GSKLRFSISGPVFSVDRDSGVVRLRQSLDREQQDTVEVIISLTDEGVLGTEPNTVSLRREIP 126

  Fly   217 ------------GRYYDFQVSVKDTKGGMTTQLCSITATNFTTPHDLIFPHKPGIIMIPEDAKRG 269
                        ||.|...:| :.||.|     .::|.|             |.|:...:|....
Mosquito   127 IRDYNDNPPVFVGRPYSATIS-EATKPG-----SNVTVT-------------PDIVATDQDEGAN 172

  Fly   270 TELDYVIARKNPLFQKPVYLELWGS----PLFAIRQKIVSSETTEGTVFLLGPLDFEKQAMYHLT 330
            .||.:      ..:|.|..    |:    .:|.:..:.::.......:.|..|||||.:..|.||
Mosquito   173 AELTF------SCYQDPAK----GADDICDVFTVHTEKIAQGKFGAWIELRRPLDFETRPSYILT 227

  Fly   331 ILANDAYAEPGQDSRNIAGMEIVVIVQDVQDQPPVFTSAPPVTKLPPGILPGDKILQVHAEDGDK 395
            |.|.|  ..|....|.:|.:.|.::  |||||||:|.:||....:|...:.|.::|.::|.|||.
Mosquito   228 IQARD--GSPTNSLRAVASVAITIL--DVQDQPPIFINAPYSATIPENTIEGTRVLTINATDGDT 288

  Fly   396 GNPREVRYGLVSENNPFTSFFDINETSGEIFLMRPLEDIAFITHVG------DPVL------LTV 448
            |:|..:.  |:.||.|. ..|.:|      ::..|...:|.:...|      ||::      .|.
Mosquito   289 GSPNPLM--LMLENEPM-GHFKLN------YIGHPRSGVAELITTGKPLDREDPIITQNGGAYTF 344

  Fly   449 IAEEVKVGRDEPPALASTVQLAFFLPDRTNSPPYFENDHYVSRVDENAPHGT---ALTFVDPYVP 510
            .....::..:|.|..::|.|:...|.|..:..|.|....|...:.||....|   .|..|     
Mosquito   345 SIRATELINNELPGDSTTSQITIVLTDVDDHVPEFSQPAYEVSIPENLEQDTPLPGLAIV----- 404

  Fly   511 RVYDDDTGKNGVFSLTLL---NNNGTFEISPNVAERSAGFLIRVRDNSMLDY----EQQQSVQFQ 568
             |.|.|.|.|..::|.|.   |:.|.|.:.|...|.....:::|.|:|.|||    |:.::.:||
Mosquito   405 -VTDRDLGPNSHYTLALRNLHNSEGVFAVVPTQGEGRTPIVVKVLDSSRLDYDVPSEEAKTFRFQ 468

  Fly   569 ILAQELGPATNLSALVNVTVYINDVNDNAPVFEQPAYSVELPENMTAGTKVVQVLATDPDSGLGG 633
            ::|...|..   .:..||||.:.|.|||:|.|.|.:||:::.||...|.|:..:.|||.|:|:.|
Mosquito   469 LVASVDGEE---KSTANVTVRLQDANDNSPTFPQASYSLQVRENSPQGFKIADLSATDHDAGMFG 530

  Fly   634 KVRYTAILGYLNTSLNLDAETGLITVSTNKHGFDREVMPEYHLYVEARDMDGEGNRAQVPLIIKL 698
            ::.| |:.|:...........|.:.|   :...|.|....|.|.:.||  ||.|......:.|.:
Mosquito   531 QLAY-AVKGFGAEFFRTHPTEGGLYV---ERQLDYEEQKSYSLALVAR--DGGGRETNANVFIDV 589

  Fly   699 IDVNDETPIFDKDLYEFILTHDLMGFTTTAVIHAEDKDA-TAPNNEVRYEI-----INGNYDNQF 757
            :|.||..|.|:...|...:......|.....:.|.|.|. |.....|.|.|     |:|:.   |
Mosquito   590 MDENDNHPAFEALEYTRTIREGATEFEPQFFVRAVDVDGPTQGGGRVSYAIESENSISGHV---F 651

  Fly   758 VLDKVTGELTVREKIHLRSKKNAKTRRRRQAGSDDEDTDIFILTARAYDLGVPVRFSTTTIRVYP 822
            .:|:.:||:.:                .|...|.|.|...:.|...|.|.|||...:.|.:.|..
Mosquito   652 TVDRDSGEIKI----------------TRPVSSMDTDRGQYELLVVATDHGVPPLKNDTRVLVRV 700

  Fly   823 PESRKRSVKF---------VVPGHNPDKAKTEETLSALSGGKVYIHNIRPLSPDEPGAKDIPAGN 878
            ..|..:...|         .:||....:|...|  :|.:|     :|:..:|..:|...|     
Mosquito   701 GLSGNQRPIFRGHATAGNRDIPGPPSYRASIPE--NAPAG-----YNVTQVSATDPDGLD----- 753

  Fly   879 PGIKERSVVTAT---VIYDSSSVVDISEIQQRLSHHNN--SYAIMPQ---------DTSSTDTLT 929
             .:....:|.|:   ||.|.:.::.::. ..||....|  ||||:..         :|::|....
Mosquito   754 -ELLRYKIVGASDNFVINDLTGLITVTR-DARLDRDTNPESYAIVVNAIDAGFPIPETATTTVHV 816

  Fly   930 PLQ--------------TQYKAENKVLFWLLIL-------LATLVALTILILLLCCICSWCPL-- 971
            .:|              |.|.:|...:...::.       |:..:..|::..:........||  
Mosquito   817 KIQDINDKPPKFTQQSYTAYVSERSAIDSEVLRVTAKDTDLSARIEYTLVEPITAVTKGGIPLLT 881

  Fly   972 ----------------------------YGAATKRIVNISRTEDDVHLVHREMANGKQTKSVQV- 1007
                                        |.|.....|..:.|..::: ..|:....:.|..||. 
Mosquito   882 TSSYDYRQAFRIDRDDGTIFVNSTLNYNYAAVITLTVRATDTAAELY-PERQFDQTEVTLYVQSF 945

  Fly  1008 --AEWMGRRDAWSAEKP-----------------------PDTRTKPTRWEFH----DGREQLDE 1043
              ...:.|...||..:|                       |......|.:|..    ||...|:|
Mosquito   946 KDTNPLFRNKGWSTVRPKIEVKVKEEAPVGSVVFRIEADDPVADVPITDFELMMPDVDGIFGLNE 1010

  Fly  1044 DVGRGQDIGEGDRRHIQSAEEQQRRVRIKHNRTAKDDL-----------HLNFHNSRTNLIND-- 1095
            ..|....:              ||.....:|:|..|.:           .|.:.|.....:||  
Mosquito  1011 RTGEIMLL--------------QRLDYETYNKTTIDFVVKAITSNRKRHSLAYVNVTVENVNDNA 1061

  Fly  1096 ----RDVYMEDVIENRDLAGDR-EHITRTRVNRQEYARRKQYDSEVRHIDDDSMRRHEIDR---- 1151
                ||.|...|:|:     || .|:..|         ....|.:|...:.|::..:.:.|    
Mosquito  1062 PVFERDSYRVTVLES-----DRYPHVVTT---------VSATDQDVVRTEKDTLLGYNVIRYSLF 1112

  Fly  1152 GSDIDFNTAHNSLKSKRELFIKDGNV------EILQLM----------------TRDKTRDGLNL 1194
            ||..:..|..|   ...|:.|..|.|      .:|:|:                |.:...|.|::
Mosquito  1113 GSHSNLFTIDN---QTGEIRIGPGQVLDREKQSVLKLIVVAEDAPGRPQDAKKATTEVMVDVLDV 1174

  Fly  1195 DDDNIYVNVPLKPAGNLSH----PQLLMVD-------------NTGKEILMRRFIEEQPDGKQII 1242
            :|     |.|:  .|..|:    |:.::||             ..|.|:......|.:.:|...|
Mosquito  1175 ND-----NAPI--FGQRSYTAVIPENVLVDTFVIAITAHDPDEGLGGEVRYDILNEGEANGLLQI 1232

  Fly  1243 R------------------EHYQIVPGATYIQSMPNEVQQGSTLKGD---TFPLGKSGPNSIVYS 1286
            .                  |.|::|..|   |....::.:.|:|..|   |..:|....|..:..
Mosquito  1233 NPKTGEIKTKAMLTGKGRAEPYELVIRA---QDSGGQLPKQSSLYNDVSFTLYIGDISANDGIPF 1294

  Fly  1287 QLEPEVKVIHTQPVQAGEGVSLDQQM-----QPAVSNQSLTHELEHSLKQ--------QNALLRQ 1338
            .:.|:|.........|..|..:.|.:     .||..:.:|.:.::..::.        :..|:..
Mosquito  1295 FIAPQVGQTANVTENATVGAPVFQVIASDPDSPATPSGTLRYRIQSDIEDAKSFNINAKTGLITT 1359

  Fly  1339 ILMEKEKLENAYTQHEVALETQSL--PGQSMAIGTQTDCDAGTQTEGFDGVLD---------PEI 1392
            ......::::||   .:.:|...:  |.|:..:..:.:            |||         .|:
Mosquito  1360 TRSLDREIKSAY---NIIIEVSDMGEPPQASTVVLRIN------------VLDIDDHEPRFVREV 1409

  Fly  1393 SLAKPSRRRARSEN------------DESMSE---------DGYEYVRFNPPNSPEGVYWIKRRR 1436
            . |:|.......|.            ||.:..         ||.|...||               
Mosquito  1410 E-AQPYELEVLEEQPAGTIVGNVSALDEDVGPNGAINYIIIDGNELGLFN--------------- 1458

  Fly  1437 TKKRPRQPRKRIVMVEEVKRKIRTPIKEEEEVQERKKRVPPKKPL-RET-----------KTSIL 1489
                       :...|:.:..|||                 |||| |||           |.:.:
Mosquito  1459 -----------VTRTEDNQAIIRT-----------------KKPLDRETLESVRLTIRCFKLNTV 1495

  Fly  1490 RKQLSDES--RKDQSR-----------------NGESQT-GNRHRSESDS--HNRDMFMEITDSM 1532
            ...|:.||  |.|:|:                 ..|:|| |.||....|:  .|...|.|     
Mosquito  1496 PDPLTHESYNRHDKSQLQLLIRVLDIDDHAPRFERENQTIGIRHNVPIDTPIANGRAFDE----- 1555

  Fly  1533 DELASPGSHSIRKIQ-VEKYYKHSDGDFDEDDTEYSIDSDGDEIVIRTNYPSRAQENERYRRQER 1596
            |..|.|..:||:.|. |.::|:. |...:|....:|::.|..||                    |
Mosquito  1556 DPTARPIVYSIQSINFVPQFYRR-DNRTEEYGDVFSLNPDTAEI--------------------R 1599

  Fly  1597 TYAEPENPVDRKRPARKSSPTDSQPEAMPRLSRRDSSKRGSRKQTSSEPPHNRVSISKYESTVTE 1661
            |.....|.|            |...:.|.|.:..|.::|                       ::|
Mosquito  1600 TTRSMSNFV------------DGYFQLMVRAANSDEAER-----------------------ISE 1629

  Fly  1662 NGRKLMSTSTEIVGSKRSLTDRSYQSETELAG------LEHEERNVPKYMEW-YYNKKKSSVSGR 1719
            ...|:.     ::..|..|.....:..||::|      :|.:||.....:|. .::.:..|....
Mosquito  1630 TQMKIF-----VIRDKSLLRFVFSRPPTEVSGVLDRFTVEMQERLANANLELSVFDAQVLSQPDH 1689

  Fly  1720 TSTESSKSQPSSKKKVGAAEKRVSKTRITAQPKDVEEYDETGGRYKPEP----APRKSPP 1775
            :...||.|......:.|:|...|...||....:..|...|...||....    |..|.||
Mosquito  1690 SLDFSSTSSCFQLTRHGSALTPVEMMRIMDDAEMKETLAEVYHRYSVHKIDSCAVSKKPP 1749

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cad86CNP_001247033.1 Cadherin_repeat 260..361 CDD:206637 25/104 (24%)
Cadherin_repeat 372..469 CDD:206637 24/108 (22%)
Cadherin_repeat 487..596 CDD:206637 35/118 (30%)
Cadherin_repeat 605..703 CDD:206637 28/97 (29%)
Cadherin_repeat 728..820 CDD:206637 24/97 (25%)
AgaP_AGAP006256XP_316322.4 Cadherin_repeat 42..133 CDD:206637 23/94 (24%)
Cadherin_repeat 141..254 CDD:206637 34/145 (23%)
Cadherin_repeat 263..375 CDD:206637 28/120 (23%)
Cadherin_repeat 384..493 CDD:206637 35/117 (30%)
Cadherin_repeat 501..595 CDD:206637 29/99 (29%)
Cadherin_repeat 603..700 CDD:206637 27/115 (23%)
Cadherin_repeat 726..823 CDD:206637 23/110 (21%)
Cadherin_repeat 832..949 CDD:206637 15/117 (13%)
Cadherin_repeat 964..1060 CDD:206637 16/109 (15%)
Cadherin_repeat 1068..1177 CDD:206637 25/130 (19%)
Cadherin_repeat 1185..1290 CDD:206637 19/107 (18%)
Cadherin_repeat 1303..1401 CDD:206637 15/112 (13%)
Cadherin_repeat 1413..1524 CDD:206637 27/153 (18%)
Cadherin_repeat 1540..1637 CDD:206637 29/162 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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