Protein Alignment TTLL15 and Ttll11

DIOPT Version :10

• Sequence 1: NP_650021.1
• Gene: TTLL15 / 41300
• FlyBaseID: FBgn0037838
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_084050.1
• Gene: Ttll11 / 74410
• MGIID: 1921660
• Length: 727
• Species: Mus musculus
• Alignment Length: 573
• Identity: 129/573 - (22%)
• Similarity: 229/573 - (39%)
• Gaps: 131/573 - (22%)

  Fly     3 ASVVENAP----NQKEVD----GKMATTEESEKPSNSIGLLPIMIFL-AATVATAVVVEVLPHA- 57
            |:..|:.|    .|:.||    |.....|..|:|.: :|.:|..... |.....|.||..||.|
Mouse    26 AAATESLPAETEKQQGVDAGAAGDPERLELEEQPKD-VGRIPTPTRRHAPEEGEARVVRRLPPAL 89

  Fly    58 -----------------------SRVFPWKLADSSADQLQPPPTYAIFGRSPTEEHLVHVVNVLH 99
                                   |||:     ..||..::|....:...|:..:...:.:..:..
Mouse    90 PLAQPRPAARALSQLVKARGRSRSRVY-----RRSAGSMRPVTVDSSKARTSLDALKISLRQLRW 149

  Fly   100 K---FGYKRVGVNDSWNLLWAHDYPFLSFANLKNLGQHQVVNHYPGCGYLTNKV----------D 151
            |   || :|:..:..|:.:...|...||       ||   ||.:||...:..||          :
Mouse   150 KEFPFG-RRLPCDIYWHGVSFRDSDILS-------GQ---VNKFPGMTEMVRKVTLSRALRIMQN 203

  Fly   152 LCTTQLPFLPRAFRLPAEREEFLDYARE----NP--QALFVQKHNEHRH----IKVRAPAD---- 202
            |...:..|.||::.||.|.:.|:...:.    :|  :..|:.|.:....    ..::.|.|
Mouse   204 LFPEEYNFYPRSWILPEEFQLFVSQVQTVKEGDPSWKPTFIVKPDSGCQGDGIYLIKDPCDGRLT 268

  Fly   203 IAFGSNDSFVQEFVQRPYLVDGHKFDIGVYVVITSVNPLRVYIYTGDVLFRYCPVKYHPFDAENV 267
            ....:..:.|||::::|.|:|..||||.:||::.|::||.:|| ..|.|.|:|...|...:.:|:
Mouse   269 GTLHNRPAVVQEYIRKPLLIDKLKFDIRLYVLLKSLDPLEIYI-AKDGLSRFCTEPYQEPNPQNL 332

  Fly   268 DKYIVGDDYLPTWEVPSLRKYYNRF-------GGSMRTVFEAYVR--DQGKDPAQIWPQVEHIVR 323
            ....:   :|..:   ||..:..:|       .||.||......|  .:|.|..::|..:..:|.
Mouse   333 HHVFM---HLTNY---SLNIHSGKFVHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISLVI 391

  Fly   324 TTIAAKEKDI-----VNILRSYRTHNFFDLMRFDLFIDEDLKVFLMEANMSPNLSSAH---FKPN 380
            .|:.|...::     .:|.........|.::.||:.:.::||..|:|.|.:|::...|   ..|.
Mouse   392 KTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPMLLEVNANPSMRIEHEYELSPG 456

  Fly   381 ------SLLYEQVLYSVF--NLVGIRPLTSTSGA-----------LLGESSEMITTDKNLSTDLN 426
                  ||:.|:|..:|.  .|..:.||......           .:...|:.:::.|:..:.|:
Mouse   457 VFENIPSLVDEEVKVAVIRDTLRLMDPLKKKKEIHFPDIYMDRKHRIPPVSDRMSSWKHKGSSLS 521

  Fly   427 KCAAHDCDKSCNKEE---CDLCLQCLSGSEYKMLQQAHQEHLHRVDMKRIFPK 476
            ...:...:||...:|   ||     .:|.:.:...:|   ||..:.:|::|||
Mouse   522 IVRSQQMEKSFTSKEDLNCD-----PTGGDSEPNPEA---HLPSICLKQVFPK 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL15	NP_650021.1	TTL	134..395	CDD:397308	74/309 (24%)
Ttll11	NP_084050.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..88		18/62 (29%)
		CPSase_L_D2	178..445	CDD:473076	68/276 (25%)
		c-MTBD region. /evidence=ECO:0000250|UniProtKB:Q8NHH1	464..566		21/109 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	530..551		6/25 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	694..727