Protein Alignment TTLL15 and TTLL1

DIOPT Version :10

• Sequence 1: NP_650021.1
• Gene: TTLL15 / 41300
• FlyBaseID: FBgn0037838
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_036395.1
• Gene: TTLL1 / 25809
• HGNCID: 1312
• Length: 423
• Species: Homo sapiens
• Alignment Length: 362
• Identity: 85/362 - (23%)
• Similarity: 154/362 - (42%)
• Gaps: 97/362 - (26%)

  Fly    94 VVNVLHKFGYKRVGVNDSWNLLWAHDYPFLSFANLKN---------LGQHQVVNHYPGCGYLTNK 149
            ::|...|.|:.:|..|:.||..|      :|...::|         |...|:|||:|....||.|
Human    16 LINNFEKRGWVQVTENEDWNFYW------MSVQTIRNVFSVEAGYRLSDDQIVNHFPNHYELTRK 74

  Fly   150 VDLCTTQ--------------------------LPFLPRAFRLPAEREEFLDYARENPQALFVQK 188
             ||....                          |.|:|..:.|||:...|::..|::|.:.::.|
Human    75 -DLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEEFRKSPSSTWIMK 138

  Fly   189 H------------NEHRHIK-----VRAPADIAFGSNDSFV-QEFVQRPYLVDGHKFDIGVYVVI 235
            .            |:...||     .:..:.::..:.:::| ..::..|.|:.|.|||:.:||::
Human   139 PCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNPLLIGGRKFDLRLYVLV 203

  Fly   236 TSVNPLRVYIY-TGDVLFRYCPVKYHPFDAENVDKYIV----------GDDYL----PTWEVPSL 285
            ::..|||.|:| .|  ..|:|.|||.|..:| :|...|          |:||.    ..|.|.:|
Human   204 STYRPLRCYMYKLG--FCRFCTVKYTPSTSE-LDNMFVHLTNVAIQKHGEDYNHIHGGKWTVSNL 265

  Fly   286 RKYYNRFGGSMRTVFEAYVRDQGKDPAQIWPQVEHIVRTTIAAKEKDIVNILRSYRTHNFFDLMR 350
            |.|.....|...|             ::::.::..|:..::    |.:..::.:.:  :.|:...
Human   266 RLYLESTRGKEVT-------------SKLFDEIHWIIVQSL----KAVAPVMNNDK--HCFECYG 311

  Fly   351 FDLFIDEDLKVFLMEANMSPNLSSAHFKPNSLLYEQV 387
            :|:.||:.||.:|:|.|.||:|:|:......|.|..:
Human   312 YDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLI 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL15	NP_650021.1	TTL	134..395	CDD:397308	74/313 (24%)
TTLL1	NP_036395.1	TTL	59..364	CDD:397308	74/313 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	391..423