Protein Alignment TTLL15 and Ttll8

DIOPT Version :10

• Sequence 1: NP_650021.1
• Gene: TTLL15 / 41300
• FlyBaseID: FBgn0037838
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: XP_006521018.1
• Gene: Ttll8 / 239591
• MGIID: 1922902
• Length: 928
• Species: Mus musculus
• Alignment Length: 607
• Identity: 106/607 - (17%)
• Similarity: 184/607 - (30%)
• Gaps: 270/607 - (44%)

  Fly   108 VNDSWNLLWAHDYPFL------SFANLKNLGQHQVVNHYPGCGYLTNKVDLCTT--QLP------ 158
            ::|..:.|..::.|:|      ...:..:|...|::|||......|.|:.||..  .||
Mouse   261 IHDVMSRLVKNEIPYLLWTIKRDVVDYHSLTCDQMLNHYGKTASFTTKIGLCLNMRSLPWYVQAN 325

  Fly   159 ---FLPRAFRL--PAEREEFLDYAR---------------------------------------- 178
               |.||.:.|  .:|::||||..|
Mouse   326 PNTFFPRCYGLCTESEKQEFLDDFRRTVAASILKWVVLHQNYCSKVKGKSKKEEAKNSDPSPKKD 390

  Fly   179 -ENP--------------------------------------QALFVQKHNE---------H--- 192
             |||                                      :||..::.|:         |
Mouse   391 PENPDLKLPSLSGQVVDTACKVCQAYLGQLEHEDIDVSEASTEALSEEEWNDLTQQYYLLVHGNA 455

  Fly   193 -------------------------------RHIKVRAPADIAFG-------------------- 206
                                           |:|.:..||..:.|
Mouse   456 SITDSKSYFAQCQALLSKISSVNPQTEIDGIRNIWIIKPAAKSRGRDIVCMDRVENILSLVAADS 520

  Fly   207 ----SNDSFVQEFVQRPYLVDGHKFDIGVYVVITSVNPLRVYIYTGDVLFRYCPVKYHPFDAENV 267
                .|...||::::.|.|:...||||..:.::|..|||.::.|....| |:...:   |..:.:
Mouse   521 QTTKDNKWVVQKYIETPMLIYDTKFDIRQWFLVTDWNPLTIWFYKESYL-RFSTQR---FSLDKL 581

  Fly   268 DKYI----------VGDDYLPTWEVPSLRKYYNRFGGSMRTVFEAYVRDQGKDPAQIWPQVEHIV 322
            |..|          :.:|.    |...|...:|.:   ..|.|:.|::.:|:  ...|..:.:
Mouse   582 DSAIHLCNNSIQRRLKNDK----ERSPLLPCHNMW---TSTRFQEYLQKRGR--GGTWGSIIY-- 635

  Fly   323 RTTIAAKEKDIVNILRSYRTH-----NFFDLMRFDLFIDEDLKVFLMEANMSPNLSSAHFKPNSL 382
                .:.::.:.|.:|..:.|     |.|:|...|..:..|.|.:|:|.|.||.:     .|::
Mouse   636 ----PSMKRAVTNAMRVAQDHVEARKNSFELYGADFILGRDFKPWLIEINSSPTM-----HPST- 690

  Fly   383 LYEQVLYSVFNLVGIRPLTSTSGALLGESSEMITTDKNLSTDLNKCAAHDCDKSC---NKE---- 440
                            |:|:...|.:.|.:..:..|:.|            |::|   |.|
Mouse   691 ----------------PVTAQLCAQVQEDTIKVVVDRKL------------DRNCDIGNFELLWR 727

  Fly   441 ----------ECDLCLQCLS--------------GSEYKMLQQAHQEHLHRVDMKRIFPKPIRDP 481
                      ..|||::.:|              |....:|....:....|..|:.:. :|.|..
Mouse   728 QPAVELPPFNGSDLCVEGISVKKAKKQMPPIASVGLSESLLDAPPKVRSARALMETVI-RPPRTT 791

  Fly   482 MRFDVMAETANMSKKNAWMTRW 503
            :|.|...|.|.:..     |.|
Mouse   792 VRQDWKREEAKVLS-----TTW 808

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL15	NP_650021.1	TTL	134..395	CDD:397308	75/434 (17%)
Ttll8	XP_006521018.1	TTL	<487..709	CDD:397308	52/262 (20%)