Protein Alignment CG14692 and CDKN2AIP

DIOPT Version :9

• Sequence 1: NP_650019.6
• Gene: CG14692 / 41298
• FlyBaseID: FBgn0037836
• Length: 2851
• Species: Drosophila melanogaster
• Sequence 2: NP_060102.1
• Gene: CDKN2AIP / 55602
• HGNCID: 24325
• Length: 580
• Species: Homo sapiens
• Alignment Length: 576
• Identity: 141/576 - (24%)
• Similarity: 240/576 - (41%)
• Gaps: 124/576 - (21%)

  Fly  1064 GKSKESLEDAGD-----ENRAVEEIIDIT-----------------ENDRSTLLENLPSSEKENS 1106
            |.:..|.::|.|     .||.::::|..:                 .:...::.|.:..::....
Human    51 GAASASTDEAADAESGTRNRQLQQLISFSMAWANHVFLGCRYPQKVMDKILSMAEGIKVTDAPTY 115

  Fly  1107 TSLDENPLPEKE---STSLD--EKPSSGTEKSTSLDEKSSSEKE----KSTSLDEKPSSEKE-KS 1161
            |:.||.....|:   |:|.:  |:||    |...::.|:||..|    |:::..|:.|:::| .|
Human   116 TTRDELVAKVKKRGISSSNEGVEEPS----KKRVIEGKNSSAVEQDHAKTSAKTERASAQQENSS 176

  Fly  1162 TSLDETPSSEKENSTSLDEKPSPEKESTSLDEKPSSGTEKSTSLDEKSSSE-KEKSTSLDEKPSS 1225
            |.:.....||..||.          .|:.:..:.||.::...|:..:|||. ..:.|:.....:|
Human   177 TCIGSAIKSESGNSA----------RSSGISSQNSSTSDGDRSVSSQSSSSVSSQVTTAGSGKAS 231

  Fly  1226 EKEKSTSLNERPSSEKENSTSLVE--NPSPEKEST-SLDEKPSSGTEKSTSLDENPSSEKEKSTS 1287
            |.|         :.:|..|.|.|.  ..|.....| |.|.:..||:.|.::|
Human   232 EAE---------APDKHGSASFVSLLKSSVNSHMTQSTDSRQQSGSPKKSAL------------- 274

  Fly  1288 LNERPSSEKENSTSQDEKP------SSETEKSTSLDEKPSSEKEKSTSLDGKPSSEKEKSTSLDE 1346
              |..|:....|:|:.|.|      |||.|... |..||||| ..|:.|..|.|||...|:|:.:
Human   275 --EGSSASASQSSSEIEVPLLGSSGSSEVELPL-LSSKPSSE-TASSGLTSKTSSEASVSSSVAK 335

  Fly  1347 NPSSEKEKSTSLNERPSSEKENSTSLVENPSPEKESTSLDEKPSSGT-----EKSTSLD--ENPS 1404
            |.||   ..|||....||...|::.|....:.:..::.|..|.||.|     .|||||.  ...:
Human   336 NSSS---SGTSLLTPKSSSSTNTSLLTSKSTSQVAASLLASKSSSQTSGSLVSKSTSLASVSQLA 397

  Fly  1405 SEKEKSTSLNERPSSEKENSTSQDEKPSSEKEKSTLLDKNTDLMRDLIQVSQKVDEEMSKGKA-- 1467
            |:....||.::.||    .||||..: ||.|....|.:::       ::..|.....:.|..|
Human   398 SKSSSQTSTSQLPS----KSTSQSSE-SSVKFSCKLTNED-------VKQKQPFFNRLYKTVAWK 450

  Fly  1468 AIAVVDL-PDINKGESVNSPLEKKPSSQE-----LEDIQAELSTDKETGEPYNLSAEKHSESETS 1526
            .:||... |::|.||.:|:.:|...::.:     |::: |:|..:|.:.|  ::..|...:|...
Human   451 LVAVGGFSPNVNHGELLNAAIEALKATLDVFFVPLKEL-ADLPQNKSSQE--SIVCELRCKSVYL 512

  Fly  1527 NKPNNTTSKEIEGEDSRDHTK-------VEPISKKTIETTDVVDVGLKGNDDPSKP 1575
            ......:.:..:...||:..|       |..|.|:....:::.|:.|.  |:.|:|
Human   513 GTGCGKSKENAKAVASREALKLFLKKKVVVKICKRKYRGSEIEDLVLL--DEESRP 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14692	NP_650019.6	DD_R_PKA	9..43	CDD:295380
		DD_R_PKA	82..120	CDD:295380
		LRIF1	<1113..1428	CDD:292369	96/341 (28%)
CDKN2AIP	NP_060102.1	XTBD	19..124	CDD:314776	11/72 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	129..356		76/269 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S8375
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.950