Protein Alignment CG14692 and Map4

DIOPT Version :9

• Sequence 1: NP_650019.6
• Gene: CG14692 / 41298
• FlyBaseID: FBgn0037836
• Length: 2851
• Species: Drosophila melanogaster
• Sequence 2: XP_006243875.1
• Gene: Map4 / 367171
• RGDID: 1564359
• Length: 2203
• Species: Rattus norvegicus
• Alignment Length: 2515
• Identity: 477/2515 - (18%)
• Similarity: 828/2515 - (32%)
• Gaps: 755/2515 - (30%)

  Fly   461 ESELIVDNKTSLDLETLSQVEVKAENKSK-------DYKSASEDQLKSNKSLDAEQETHVDSKDK 518
            |.|:..|...:|:.|....:..:...|::       |.||.:.:. |....:|..|...:.|...
  Rat    18 EGEIKRDFMAALEAEPYDDIVGETVEKTEFIPLLDGDEKSGNSES-KRKPCVDTSQVEDIPSSKP 81

  Fly   519 PLANDLDDAIKAED---SSSDLLRENRE-EDSALHRNTEKKESEDVQENIVESAIASSNNAR--N 577
            .|..:.|..::..:   |.:|.|.||.: ||   ::|:: ...||.........:..:|.|.  |
  Rat    82 TLLANGDHGVEGNNTTGSPTDFLVENVDYED---YQNSQ-SWPEDASFCFQPQQVLDTNQADPFN 142

  Fly   578 VEKEDEIIPLPKIQNSKSQLQEISLKNKITPTVSIEIEHVEDILEDSSASPNDSKADDLTEGI-- 640
            |..:|.:..|..:.:..:.......:|.       .:|....:|...|.:|....:.:.:.|.
  Rat   143 VHHDDGLADLLFVSSGPTNASAFIEENN-------PLEDSYGVLPCDSFAPTAVVSQEWSVGAPD 200

  Fly   641 SVTEEPKSIPNVEVDSL-------KSILINHNLEGCEQETSAETIVDINFEAAAAKQDIDSNEMI 698
            |...||...|.|.:::.       |::    :||..:::..|:.   :...|......:.|.|..
  Rat   201 SPHSEPCVSPEVTIETAQPATELSKAV----DLESVKEQLPAKA---LEMMAGQTTDAVPSKESE 258

  Fly   699 QSSDTHEKIREKRSIEYEDNVQLNSDSQNVLIAE--SPIDQEQLKINNDQTLEL--------DRK 753
            .|.||.........:....::: .|.|.:|:.|.  .|..:..:.:..:..|.:        |..
  Rat   259 GSPDTDAAPGPDTDVTLTKDIE-ESSSPDVISANVTQPFTESDMFLTQEMELLIGTEAAQVKDTM 322

  Fly   754 PEIIPKVEDVPKTTPNTKDDEVSGS--------------------TEKLEMNKEEPLD-----ET 793
            ..:.|.:.....|.|.|:::.|.|.                    .|.:.:.||..|:     .|
  Rat   323 SSVEPDISSAKNTAPPTEEETVPGKDMTFPKEAETALPIEMDLAPPEDVALPKETELELAPAAGT 387

  Fly   794 VELSNHEITLSK--VLKTVSENKQERMEDLPSEDKIV--KDSTSSLAEDSKMPEAKKESKSIDEL 854
            ..||..|:.|:|  ...|.....||.:  |.||.::|  .||..:|.::..:|           |
  Rat   388 APLSETEVALAKDEEPSTGIPAAQEML--LSSETEVVLPSDSIMTLTKEVTVP-----------L 439

  Fly   855 ETTKEVLEDIIHSETDLSKQNIKENVEETDKPQSDDSPKELENLKDKIKMLTQEEVTPIEPES-- 917
            |....::.|:             ..:.||:......:....|....|:|     ::.|: |||
  Rat   440 EAAGPLVSDM-------------TAILETEMTLGGGTATPTETKLGKVK-----DMAPL-PESEV 485

  Fly   918 ---------LETKGLLSTDKNDKNSLFSKTNSEENNNESQNVDDITEKTDLKNEKHLLASHISVT 973
                     .|||   .|:.|:...|     |||   |..::.|::...:.:..|:  |...|.|
  Rat   486 ALGKDVVTLPETK---VTEFNNVTPL-----SEE---EVASIKDVSPSPETETAKN--ADLHSGT 537

  Fly   974 SSGIDDNDIQNTAASAELSVIDGDISIRESETKHVENREEMASTNLDSDQVENMKLEGEIGQLKT 1038
            ...:|::....:..:..|......:.|::.||  |:.:||::    :..|:|:::|||
  Rat   538 ELTLDNSMTPPSDPALPLETKVATVQIKDKET--VQTQEELS----EDSQLESVQLEG------- 589

  Fly  1039 VFEQSEEKTSPTKSESLHAEDRKIS-----GKSKESLEDAGDENRAVEEIIDITENDRSTLLENL 1098
               ||.........|.:.|.|:|.:     |...|.||..           :.:.:....|....
  Rat   590 ---QSAVPPCTISPEPVKAADQKSTLPVDEGSPLEKLEQK-----------ETSGSQPPELCSGF 640

  Fly  1099 PSSEKENSTSLDENPLPEKESTSLDEKPSSGTEKSTSLDEKSSSEKEKSTSLDEKPSSE---KEK 1160
            |||:.:::..      |....::..:.|....|    |.|.||..|.....|...|.||   ...
  Rat   641 PSSQGKHACR------PSDRRSARSKPPRVPPE----LLEGSSPWKILDPRLGPCPFSELGWVSG 695

  Fly  1161 STSLDETPSSEKENSTSLDEKPSPEKESTSLDEKPSSGTEKSTSLDEKSSSEKEKSTSLDEKPSS 1225
            |:|..|..:..|........:..|.:|:..:...|....:|     :|...|:.:..:....|..
  Rat   696 SSSCGEHGTQRKVTHAEFLAQRDPGREARDVASMPLVTKKK-----KKKPKERRRPQARAGGPGD 755

  Fly  1226 EKEKSTSLNERPSSEKENSTSLVENPSPEKESTSLDE----------KPSSGTEKSTSLDENPSS 1280
            |.......:..|.:.:...:    .|.|.:.||...|          :..:.:.:.||..|.|..
  Rat   756 EDNVDGRQDHHPVAHEPQKS----GPGPSQPSTVSTEYGCVSREILKQDCAESPRVTSCPEQPPE 816

  Fly  1281 EKEKSTSLNER---------PSSEKENSTSQDE----------KPSSETEKSTSLDEKPSSEK-- 1324
            ...|: .|..|         |.||.:::..|.|          ||..:|.::.|    |||.|
  Rat   817 VMVKA-QLKPRVEDDHRDKSPLSENQDNLLQQEEERSPAVLHPKPLVDTGRAVS----PSSVKGA 876

  Fly  1325 -------EKSTSLDG--------------KPSSEKEKST----SLDENPSSE--KE-----KSTS 1357
                   |.||...|              ||::||.:|:    |:..:|..:  ||     ::|:
  Rat   877 PVDSSAHEVSTLRGGCSPLLGQEIMNRVPKPTTEKVQSSLTLPSVANHPLEDGLKEERAGSRATA 941

  Fly  1358 LNERPSS-------------EKENSTSLVENPSPEKESTSLDEKPSSGTEKSTSLDENPSSEK-- 1407
            |...|::             |.:..|||:.:..|:::  .|.:.|.|..|....:..:..|.|
  Rat   942 LQVCPNAAGDFRGRRLDTCPEPKQGTSLLASKEPKEQ--ELIQAPGSQCESFKKMTGDGKSRKGR 1004

  Fly  1408 ---------EKSTSLNERP----SSEKENSTSQDEKPSSEKEKSTLLD----------KNTDLMR 1449
                     .||...:|.|    |:::..:.....:|.||....::.|          |....:.
  Rat  1005 GPGKVRAGSGKSGGKSEVPFLLDSNKEGRAVPLPSEPVSETGVVSIKDPRRGLCLESSKQPGAIT 1069

  Fly  1450 DLIQVSQKVDEEMSKGKAAIAVVDLPDINKGESVNSPLEKKPSSQELEDIQAELSTDKETGEPYN 1514
            ||.:...:|.:|::.|.....:..|..:..|.|::..|:.: :.:..|....::|...:.|:...
  Rat  1070 DLSEAVLRVAKEVADGGVGGTMQPLIPLESGSSLSQTLDGR-TERRAEVKNVDVSNQSKEGKCTW 1133

  Fly  1515 LSAEKHS--ESETSNKPNNTTSKEIEG----EDSRDHTKVEPISKKTIETTDVVDVGLKGNDDPS 1573
            ::.|..|  ..:|..:.|...:|..:.    :.||...:.|.:|...||         |.::|.:
  Rat  1134 MNHESTSWITEKTKKRGNEGRNKRFKNNYPVQPSRMEGREEIVSPPCIE---------KQSNDGN 1189

  Fly  1574 KPGK------------------TETAATKSVSPDIKDK----DTLKL-KP---DDDSPQKSEVIT 1612
            ...|                  |.:.||:.|: |.|.|    :::.| .|   :.:|.|.|.|.|
  Rat  1190 VAHKNSVLGQISPKIHTPLFSHTSSTATEEVA-DTKSKKVESNSVTLGNPAGNETNSVQNSSVTT 1253

  Fly  1613 AELQLKSFKTPND--DGAWYDIYVEPKITAERD---LFVPPAPIETKRPNSAK------------ 1660
            ......:..:|.|  .||.:    .|.:.:|.:   ..|...|  .||.|..|
  Rat  1254 EPAAKVTDVSPQDPIQGAGF----VPLVKSEENTGQTAVVGKP--NKRSNDGKYKKVKNSFPEKH 1312

  Fly  1661 --EVASVVEEPM---------------------IISERTP----SYYTPKEIVESVK------PK 1692
              |:.:....||                     ..|.|.|    |...|.|.:||..      |.
  Rat  1313 ILEINTETTNPMKTTGDCRIEGMGYMDENRNITFTSGRAPSGLMSKSAPLEAIESAGCEMLPCPT 1377

  Fly  1693 P---KNSVSF------------FVSFDSD----DGKPKYKIPKRFQSQSNKNAQKEVKAIEATQS 1738
            |   |...||            |..|..|    ||.|           ..:|.:....|:.:|.|
  Rat  1378 PQVGKEDNSFPDSSRKSEQDNNFKLFAQDMCSKDGVP-----------GQENPKAPPAAVPSTTS 1431

  Fly  1739 ESDIDSNEEEIEIIEVSEGDPEYQQTGGTKLQTILELDNENEMTYEFNSQGQGLELNLNESNVEK 1803
            ...:.....|.:....|.||...:..||..               ::::.|:|  |......|.:
  Rat  1432 TEGVAGTCTEAQKKFSSLGDHSLKNKGGLA---------------DYSANGEG--LTPKSHAVGE 1479

  Fly  1804 PKSPTNSINEFETAYKTD---------ILNITRSVEIIERAYKRFKNR-----SSLKSEPGNESD 1854
            |:|..:..:|....:.|:         :|..::|:....|....:.:.     |.:|.|...|.|
  Rat  1480 PESEQHGSSEHPAQHATEPAKGYLLPGVLTESQSLPEEVRVLDSYADSGDLPVSLMKEEKRTEKD 1544

  Fly  1855 FENQNRAAIVIQKWVRN--TLKQKAYDTQKSKQSLAARKIQRAYRRYVEKAKQRTQKQEMAALII 1917
                       ...|||  .|:|||     .|.||...          :..|:|..|
  Rat  1545 -----------SAPVRNPDPLRQKA-----QKFSLCDN----------QNKKERDSK-------- 1575

  Fly  1918 QKAFIRYSHRIRTEPNKTQSLVNI----------ELKQNNAA---FKIQRAYRRYLKLQSERHQD 1969
                         .|......|:|          :||:.|.:   .|::........|||:...|
  Rat  1576 -------------GPESLDKKVDITLLPPENEKAKLKETNLSCEVTKLECISMLTTALQSDFSCD 1627

  Fly  1970 AGIPVKDDSVSLINSVKLPTEPEIVNKLNSNDEHKVNLIPIHNQKVADYPEIIKEVQPEEPNDVL 2034
            :   |:.:|..::.:.|.|..||                             .|..:.|.|..:.
  Rat  1628 S---VEGESNVVVTAYKDPQVPE-----------------------------FKGNEVEAPQKIT 1660

  Fly  2035 REAETESNTILLSDLTEKHKE-TNEMHKKG-------------SQELASVSAEVEKPMDASKLPT 2085
            .::|       |..|.|:.|| .::|..||             ..:.||...|..|.:.||.:
  Rat  1661 GKSE-------LKVLDERKKEDKSKMAVKGYMRPTKSRGPTPHQPKSASQERERAKLLKASGV-- 1716

  Fly  2086 ENRRDEKQVV-----ETISPPINLTQLSAEPKRVKELKSDGFQEIE-NLSNANFNPKSSTKSP-- 2142
             :|::|.:..     ..|:.|.|.....:..|:.|.|.:.  |..: :.|.|...|.|..|.|
  Rat  1717 -SRQEEGKAAVGLTGNDIATPPNKELPPSPEKKAKPLATT--QPAKTSTSKAKIQPTSLPKQPAP 1778

  Fly  2143 ---DEIDLQPLEQAQKLVEIEKPSEEMKTELTNLSQASPNHPLKDDLVEKSNAALIIQRAFRQYM 2204
               ..::.:|:..|...|.............|......|...||...:.::..|
  Rat  1779 TTSGGLNKKPMSLASGSVPAAPHKRPAAATATARPSTLPARDLKPKPITETKVA----------- 1832

  Fly  2205 ERRKFENFEDSSIDSI--------TSSRITAIET-------ANYPTAGTPSRSLIQEAIGDPGDT 2254
            |:|...: :.||..::        |.|:.|:..|       :..|:...|.|....:..|.|.|.
  Rat  1833 EKRTSPS-KPSSAPALRPGPKTTPTISKATSPSTLVSTGSSSRSPSTTLPKRPTTTKTEGKPADV 1896

  Fly  2255 LEDTS--------------------NIQPKSEW---FVGSTRIIPSQGVVEGPVEVETNPDPATI 2296
            ...|:                    |..|....   .:.|||:.|........|.:..:..|.:.
  Rat  1897 KRMTAKSATADLSRSKTTSASSVKRNTTPTGATPPAGMASTRVKPMSAPCRSSVALSVDKKPTST 1961

  Fly  2297 ATTSKA----ELTTSTQVESVETVDRSHGSLES-KLNPGTIIDDCLGDASEKDNAISSGLAG--- 2353
            ..:|.|    .|.|:.....:::|....||.|: |..||.      |.|..:....::..||
  Rat  1962 KPSSSAPRVSRLATTVSAPDLKSVRSKVGSTENMKHQPGG------GRAKVEKKTEAATTAGNPE 2020

  Fly  2354 ---LAKASEALFDSVEDPLLLSQSDFGGLVQSLDIASTQELLNDFLQNEIEYSSRLGPFPSAKLL 2415
               :.||:.::..:.:.|        .|.||             .:..::.||.
  Rat  2021 PNAVTKAASSISSAPKPP--------AGKVQ-------------IVSKKVSYSH----------- 2053

  Fly  2416 EEVIEEPCIKRSASLVNVSECESESDNASQKVENTDSSISETAGLDTLSADTIDKATVKLSKP-- 2478
               |:..|    .|..|:.....   ..:.:::|....||:      :|:....||.:| .||
  Rat  2054 ---IQSKC----GSKDNIKHVPG---GGNVQIQNKKVDISK------VSSKCGSKANIK-HKPGG 2101

  Fly  2479 -EEVIEKMSQLRDSKSYERISSTD---------------------------PSFDEPVI------ 2509
             :..||........|:..::.|.|                           |:.:||.|
  Rat  2102 GDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGTVKVTEGGGSEAPPCPGPPAGEEPAIPEAAPD 2166

  Fly  2510 ----RPISSLQEQSSLDIEDGDIIVYNRLQRD-ETRESSAQSDSV 2549
                ...|.|...::|. ..||       ||: :|.:|..|..|:
  Rat  2167 AGAPTSASGLSGHTTLS-GGGD-------QREPQTLDSQIQETSI 2203

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14692	NP_650019.6	DD_R_PKA	9..43	CDD:295380
		DD_R_PKA	82..120	CDD:295380
		LRIF1	<1113..1428	CDD:292369	82/408 (20%)
Map4	XP_006243875.1	Tubulin-binding	<1981..2002	CDD:278828	7/26 (27%)
		Tubulin-binding	2042..2071	CDD:278828	8/62 (13%)
		Tubulin-binding	2073..2102	CDD:278828	9/35 (26%)
		Tubulin-binding	2104..2134	CDD:278828	5/29 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000