Protein Alignment CG14692 and pho

DIOPT Version :9

• Sequence 1: NP_650019.6
• Gene: CG14692 / 41298
• FlyBaseID: FBgn0037836
• Length: 2851
• Species: Drosophila melanogaster
• Sequence 2: NP_001002867.3
• Gene: pho / 334003
• ZFINID: ZDB-GENE-030131-5935
• Length: 2798
• Species: Danio rerio
• Alignment Length: 3234
• Identity: 621/3234 - (19%)
• Similarity: 1141/3234 - (35%)
• Gaps: 974/3234 - (30%)

  Fly    82 IPEKLTDLIKQFIKAVLREKPDNI-----YIFAQEYFQRMSKE--------KSGRIEYSKYSSYE 133
            |.:.:|.::....:....:|||:|     |:..:...:....|        :|.|.:.||:..|.
Zfish    69 ITQSVTKVVHTKRRLRSSKKPDSISDDSGYVRERRLSENQQTECEEESRSLRSSRRKRSKWEMYA 133

  Fly   134 -----------KSLKDKEHLAPATK------------VTC---------ECGRVLSANR-----K 161
                       |||| .:|| |..|            ..|         :.|:|:|::.     .
Zfish   134 SARKATFPFLMKSLK-TQHL-PIRKHQILENSEVGGFFKCIKKIKTGSVKMGKVISSHLFQSPIS 196

  Fly   162 DVENTASVYTDNKLAEADQREF------SSRISYIQSVVIIQRHFRRYLNERKIGRDKDKCNS-- 218
            |........:::.:...|:..|      .....::...:..:|....||:.   |.||:|...
Zfish   197 DSSEEEDQNSEHDVISVDKALFVPGYKRGINFKWLPDFIRERRTLENYLSN---GVDKEKKTEQI 258

  Fly   219 VDYVAAILLIQRQVRRYLAKKRVAELKNSRDAQKADAKPKAADYMKAVVVIQRHYRIYLKKKQEQ 283
            ::|        ||..::..:.....|..|....|   |||..|..:.:.....|..:.:.:..|.
Zfish   259 IEY--------RQRNQHPQRTSAKALSKSSQVFK---KPKKQDTHEVLASCSDHEDLEIAECAEN 312

  Fly   284 NRLKHGPVSLATAAIIIQRAYRRMVARHKAKRTTSIGTDQAEELNDNASE---TGSYTSVSTALL 345
            :...|        .::|:...|:.|      ...|...:..::||....|   ...:...::|..
Zfish   313 SHEGH--------KVVIEETQRQTV------EEASAHLEHEDDLNCKVVEYRKRKRHPKRTSAKA 363

  Fly   346 STESTELGMANFEERVHQKII----HEDEE----VENSNVDAG-LRKEYFAETIKGEQKSINLRK 401
            .::|:::.....::..|:.:.    |||.|    .|||:.|.. :.:|...:|:  |:.|.:|..
Zfish   364 LSKSSQVSKKPKKQDTHEVLASCSDHEDFEGVECAENSHEDHNVVIEETQRQTV--EEASAHLEH 426

  Fly   402 SEILSGALIESMICK--PDLQNIKDLNNES------KEIDVELEVNEHQ---------------- 442
            .:.|:        ||  ||:    |..|||      :|.|:..:.:..|
Zfish   427 EDDLN--------CKNQPDV----DQPNESNFIGPPQEGDISTQSDTQQTDSDIGSVDLFSPLNS 479

  Fly   443 -------------PAKLEEHITDEKKTIQDSESELIV----------------DNKTSLDLETLS 478
                         .|.:||:..|...|..:||.:.:.                .::|.:|.|:||
Zfish   480 PKRDDQIPNTTSITANVEENDQDSDVTQIESEGQHVSTFTQETQKCFANEEYDSDETHIDTESLS 544

  Fly   479 QVEVKAENK---SKDYKSASEDQLKSNKSLDAEQET---HVDSKDKPLANDLDDAIKAEDSSSDL 537
            :.|.:..||   |..:....:.:::|.|....:.||   .:..|..||:|.....:......|.:
Zfish   545 RFEPRTPNKQFTSTKHPEIPQFRVQSPKPPSRQAETVNVQLSPKHLPLSNVPLSEVPTSPCESAI 609

  Fly   538 LRENR-----EEDSAL-------------HRNTEKKESEDVQENIVESAIASSNNARNVEKEDEI 584
            :...:     |.||.:             .|..:|..:.|.:::.....:....|...    |:|
Zfish   610 VGRQKTMVETETDSPMFKITGPSFLKRKRKRTKDKNAAADFKQHDTNGDVGQMVNCPG----DDI 670

  Fly   585 -----IPLPKIQNS--------KSQLQEISLKNKITPTVSIEIEHVEDILEDSSASPNDSKADDL 636
                 ||:..|:..        ..|.:|:.||:|             ::||:|..|
Zfish   671 TGLKAIPIENIEACGVEHEMAIGEQTEELGLKSK-------------ELLEESVLS--------- 713

  Fly   637 TEGISVTEEPKSIPNVEVDSLKSILINHNLEGCEQETSAETIVDINFEAAAAKQDIDSNEMIQSS 701
                       ::.:|...|.:..:..:.::.|  |.....:|:.:.:|...|:|
Zfish   714 -----------AVNSVSTKSKREKMKKYKVKEC--EAVENQLVETSKKAKKKKKD---------- 755

  Fly   702 DTHEKIREKRSIEYED-----NVQLNS--DSQNVLIAESPIDQEQLKINNDQTLELDRKPEIIPK 759
                  :|:.:..|.:     |:|.|.  ||..:.:.|  ::|....:|.||...:....||..:
Zfish   756 ------KERIATSYPEENNLTNIQSNEGFDSAELRVKE--VNQSSQSLNTDQPTCVQTSEEITGE 812

  Fly   760 VEDVPKTTPNTKDDEVSGSTEKLEMNKEEPLDETVELSNHEITLSKVLKTVSENKQERMEDLPSE 824
            .|...|||.:..||               ||.|:|.|   ::||:... .|.....|:.|.|.:|
Zfish   813 TELKKKTTRHETDD---------------PLYESVGL---DVTLASQF-DVGLRIDEQQEGLVTE 858

  Fly   825 DKIVKDSTSSLAEDSKMPEAKKESKSIDELETTKEVLEDIIHSETDLSKQNIKENVEETDKPQSD 889
            :....:.....|  .|:.:.||:.:     :|:.:|..||                 ..||.:||
Zfish   859 EAERDERLQGKA--MKVAKGKKKIQ-----DTSFQVDHDI-----------------GLDKQRSD 899

  Fly   890 DSPKE-------LENL------KDKIKMLTQEEVTP-------IEPESLETKGLLSTDKNDKNSL 934
            ...|.       ||:|      |.|.|...:|:..|       ...:..:|..|.:||....:|
Zfish   900 SGAKPANLDLDGLESLTIKKKKKKKKKHKLKEKTDPKLDFDFDHNVQFFQTDRLQTTDSVLLDS- 963

  Fly   935 FSKTNSEENNN-ESQNVDDITEKTDLKNEKHLLASHISVTSSGIDDNDIQNTAASAELSVIDGDI 998
             :.||.::... :.||  |..:.:||| :.|::.|.:........|..::.|..|:..::::
Zfish   964 -THTNKQKKKKLKCQN--DTDQSSDLK-QLHVVGSKLQTIDLPKTDKHMERTGVSSSDALLE--- 1021

  Fly   999 SIRESETKHVENREEMASTN--LDSDQVENMKLEGEIGQLKTVFEQSEEKTSPTKSESLHA---- 1057
                    |:::|......|  :.:||:|:::...|:.:..:....|::|...|   |:|.
Zfish  1022 --------HMDDRTPGMKENNTIQTDQIEHLQTSEEVTRCSSPRLSSDKKREKT---SVHPNLDA 1075

  Fly  1058 ------------EDRKISGKSKESLEDAGD--ENRAV---EEIIDITENDRSTLLENLPSSEKEN 1105
                        ||:.|:..:.:..:.:.:  ||.:|   .::.:|...:.|.||::      .:
Zfish  1076 SSVFQFDGFKANEDQAITQNTTKEKQISSEQLENNSVGPPSQVENIANVNSSVLLDH------TH 1134

  Fly  1106 STSLDENPLPEKESTSLDEKPSSGTE---------KSTSLDEK----------SSSEKEKSTSLD 1151
            ..:|.|..|  ||.|..:...:.|.:         |:|.|.:.          ||.|..|.|  |
Zfish  1135 MNTLREGQL--KEQTYKELALAFGLKQLCIVVNKLKTTDLPKTNKNMEGTGVGSSDELLKHT--D 1195

  Fly  1152 EKPSSEKEKST----SLDETPSSEKENSTSLDEKPSPEKESTSLDEKPSSGTEKSTSLDEKSSSE 1212
            ::|...:|.:|    .::...:|||     ::.:.||.....|..:|... |...::||..|.|:
Zfish  1196 DRPLEMRENNTIQTNQIEHLQTSEK-----VERRSSPRVTRLSFAKKWMK-TSVDSNLDASSGSQ 1254

  Fly  1213 KEKSTSLDEKPSSEKEKSTSLNERPSSEKENSTSLVENPSPEKESTS---------LDEKPSSGT 1268
                  .|...|..||..|.     |...:.|....:|...:||.|.         :|::|....
Zfish  1255 ------FDGLNSMAKEDWTF-----SQNMDLSIKRTKNKQKDKERTGVSSDALLKRMDDRPPEMR 1308

  Fly  1269 EKST----SLDENPSSEKEKSTS---LNERPSSEKENSTSQDEKPSSETEKSTSLDEKPSSEKEK 1326
            :|:|    .::...:|||....|   |.....::|...||.|  |:.:....:..|....:.||.
Zfish  1309 KKNTIQTNQIEYLQTSEKVTRRSFPRLTRLSLAKKMEKTSVD--PNLDASSGSQFDGLKEASKED 1371

  Fly  1327 ST----SLDGKPSSEKEKSTSLDENPSSEKEKSTSLNERPSSEKENSTSLVENPSP---EKESTS 1384
            .|    |::.| .|:...|..|:.||:.....:.|.|..|||:.:|...|..:.:.   ::..|.
Zfish  1372 RTAPRNSIEEK-QSDAISSEGLETNPAHLVSTNKSDNTSPSSQVDNIVGLQSDANSVLLDRTHTD 1435

  Fly  1385 LDEK--------PSSGTEKSTSLDENPSSEKEKSTSLNERPSSEKENSTSQDE------------ 1429
            :.:|        ..:.|:.::.:|:|....:.......:.||....|...:|:
Zfish  1436 IRKKKKIKNKLIEQTDTQLTSKVDDNVQPFQSIELRAMDLPSKRITNKKQKDQDRTGVSSSDAVL 1500

  Fly  1430 KP----SSE-KEKSTLLDKNTDLMRDLIQV----SQKVDEEMSKGKAAIAVVDLPDINKGESVN- 1484
            ||    ||| :|.:|:...|.:.::...::    |.::.....|.|.::. .:| |::.|...|
Zfish  1501 KPLDGFSSEMRESNTIQSDNIEHLQTSEEMTRCPSPRLSSNKKKNKKSVD-TNL-DVSSGSQFNG 1563

  Fly  1485 ----------SPLEKKPSSQELEDIQ-------------------AELST------DKETGEPYN 1514
                      :..:|:...|:|::::                   .|:.|      ||:..:..|
Zfish  1564 SNGTAKEFQHTSKQKRKKKQKLKELENVGDNVHSVEPDQFSGLQITEMKTKTKRKKDKKRTKQAN 1628

  Fly  1515 ---------LSAEKHSESETSNKPNNTTSKEIEGEDSRDHTKVEPISKKTIETTDVVDVGLKGND 1570
                     ||:|...:|:|....:..||:||:|:............||
Zfish  1629 VEENDLKGILSSEAFKDSQTDQLEHIQTSEEIKGQSPNVAASKSAKKKK---------------- 1677

  Fly  1571 DPSKPGKTETAATKSVSPDIKDKDTLKLKPDDDSPQKSEVITAELQLKSFKTPNDDGAWYDIYVE 1635
              .|..||:....:|:..|      |.|..:|.:..::.  |.|.|        .||
Zfish  1678 --KKKNKTKDPQYESIDLD------LSLAKEDRTTTQNH--TEESQ--------GDG-------- 1716

  Fly  1636 PKITAERDLFVPPAP-IETKRPNSAKEVASVVEEPMIISERTPSYYTPKEIVESVKPKPKNSVSF 1699
               .|...|.:.||. |:..:....:|.|.:|:...||..::.|   ..::..||
Zfish  1717 ---NAVEHLEMNPAGLIKVSKKKKKRENAGIVQLDNIIGLQSGS---STDVNSSV---------- 1765

  Fly  1700 FVSFDSDDGKPKYKIPKRFQSQSNKNAQ-------------------------KEVKAIEATQSE 1739
             :|..:|..|.|.|..|..:.|.|..|:                         ::.|..|..:..
Zfish  1766 -LSDSTDTNKHKKKKRKTLKEQENVEAEGDDVHSVDPDQFSGLQITEMTTKKKRKHKRCEEQRCL 1829

  Fly  1740 SDIDSNE-------EEIEIIEVSEGDPEYQ-------QTGGTKLQTILELDNENEMTYEFNSQGQ 1790
            ..:.|:|       ..::.|:.||...:.|       :.||:..|    |:|.|||     ..|.
Zfish  1830 RGVSSHEAFKAPPTNLLQHIQTSEEISQCQSPNVAALENGGSPYQ----LENINEM-----QPGN 1885

  Fly  1791 GLELNLNE------------------SNVEKPKSPTNSINEFETAYKTDILNITRSVEIIERAYK 1837
            .:::|.:|                  .|||   :..|.::..|       ||:...::|.|...|
Zfish  1886 SIDINSSEILYSTCTHKQKWKKLKQQENVE---ADANDVHSAE-------LNLFSELKISEPTTK 1940

  Fly  1838 RFKNRS-----SLKSEPGNE-------SDFENQNRAAIVIQKWVRN--TLKQKAYDTQKSKQSLA 1888
            :.|::.     :||....||       |..|:...:..:.|....|  |||.:    :|.||
Zfish  1941 KKKHKKCVEKCALKDISSNEGIKAPQTSQLEHVQTSKEITQCQSPNAATLKSE----KKKKQ--- 1998

  Fly  1889 ARKIQRAYRRYVEKAKQRTQKQEMAALIIQKAFIRYSHRIRTEPNKTQSLVNIELKQNNA-AFKI 1952
             ::.:....:|:: |...:|..::..|..|....|.:.:..:|..:...:.:.:|:.|.| ..|:
Zfish  1999 -KRDETEVPQYLD-ASSVSQFDDVTRLKKQAKVDRTTTQNSSEETQNDDISSEQLEMNPAHLIKV 2061

  Fly  1953 QRAYRRYLKLQSERHQDAGIPVKDDSVSLINSVKLPTEPEIVNKLNSNDEHKVNLIPIHNQKVAD 2017
            .:        :.::.:.||.|.|.|              :||. |.|.:...||...:.:.|..|
Zfish  2062 SK--------RKKKREKAGSPYKVD--------------KIVG-LQSGNFTDVNFSQLSDSKRTD 2103

  Fly  2018 YPEIIKEVQPEEPNDVLREAETES-NTILLS-----DLTEKHKETNEMHKKGSQE--LASVSAEV 2074
            ..:..|.::.:|..:.  ||:.:. :::.|.     .:|:...:....||:..:|  |..:|:.
Zfish  2104 KQKKKKRMKLKEQENA--EADVDDVHSVELDQFSGLQITKPTTKKKMKHKRCVEESGLRDISSN- 2165

  Fly  2075 EKPMDASKLPTENRRDEKQVVETIS---PPINLTQL-SAEPKRVKELKSDGFQEIENLSNANFNP 2135
                :|.|.|..|:.:..|..|.|:   .| |:..| ||:.|:.|..|:...|.::..|.:.|:.
Zfish  2166 ----EAYKAPQTNQLEHIQTSEEITQFQAP-NVAALKSAKKKKKKRDKTVEPQCLDASSVSQFDD 2225

  Fly  2136 KSSTKSPDEI-------DLQPLEQAQKLVEIEKPSEEMKTELTNLSQASPNHPLK-DDLV--EKS 2190
            ..:....|:.       :.|..:.|.:.:| ..|:..||.......:.:...|.| |::|  |..
Zfish  2226 VKTRAKEDQTLTPNSSKETQGDDNAVECLE-TNPAGSMKVSKKKKKRENAGSPYKVDNIVGLESG 2289

  Fly  2191 NAALIIQRA--------FRQYMERRKFENFEDSSIDSITSSRITAIETANYPTAGTPSRSLIQEA 2247
            |:|.:....        ..:..:|:|.:..|....|..||..|...::.|..|.         ::
Zfish  2290 NSADVSSSVPSDSTDTNKHKKKKRKKLKKQEIVEADLQTSEEIIQCQSPNVATL---------KS 2345

  Fly  2248 IGDPGDTLEDTSNIQPKSEWFVGSTRIIPSQGVVEGPVEVETNPDPATIATTSKAELTTSTQVES 2312
            :....|..::...:...|                     |....|.:.:...:|.:.|| .|..|
Zfish  2346 VKKKKDETKEHQRLDASS---------------------VSQFDDVSRLKKRAKEDRTT-IQNSS 2388

  Fly  2313 VETVDRSHGSLESKLNPGTIIDDCLGDASEKDNAISSGLAGLAKASEALFDSVEDPLLLSQSDFG 2377
            .||......|.:.::||..:|     ..|:|.....:|  |                  |.|..|
Zfish  2389 EETQSADISSEQLEINPAHLI-----KVSKKKKKKENG--G------------------SPSQVG 2428

  Fly  2378 GLV-----QSLDIASTQELLNDFLQNEIEYSSRLGPFPSAKLLEEVIEEPCIKRSASLVNVSECE 2437
            .:|     .|.||:|:  :|:|..:.:.:.|                     |:...|......|
Zfish  2429 NIVGLQSGNSTDISSS--VLSDSTRTDKQKS---------------------KQKKKLKEQENVE 2470

  Fly  2438 SESDNASQKVENTDSSISETAGLDTLSADTIDKATVKLSKPEEVIEKMSQLRDSKSYERISSTDP 2502
            :::|         |...:||   |..|...|.:.|.|..|..:...:.|.|||      |||.|
Zfish  2471 ADAD---------DFHSAET---DQFSGLQITEMTTKKKKKHKRCVEESGLRD------ISSND- 2516

  Fly  2503 SFDEPVIRPISSLQEQSSLDIEDGDIIVYNRLQRDETRESSAQSDSVVFGDAVSENNQEKELLNE 2567
            :|..|..                      |:|:..:|.|...|..|   .:|.:.|:::|:....
Zfish  2517 AFKAPQT----------------------NQLEHVQTSEEITQCQS---PNAATLNSEKKKKNKR 2556

  Fly  2568 EESGRVHLMRHYTIAGDDPRGLFRSVTIDDALSYMENGANGMGASSFCLDDETS----ENIRKKM 2628
            :::             |.|:.|                            ||:|    ::::|:.
Zfish  2557 DKT-------------DKPQYL----------------------------DESSVSQFDDVKKRA 2580

  Fly  2629 MA------YSLSETDSDYFDPKKVSSEDFDVDTA-MADAMGTSTETESTIVSAATKIQAGARGFL 2686
            .|      .|..||..|     .:|||..:::.| :........|.:|..:.:.......:..||
Zfish  2581 KADRTTTHNSSEETQKD-----NISSECLELNPAHLMKISKRKRENKSFGLLSENTADLNSSSFL 2640

  Fly  2687 T-------RRRLRRASAGTKSSTLDTKASFGNDAISESLERFIEEEAAKKIQTAYRMHTRKRKGH 2744
            .       :::.|:...|.::...|..     |..|...::|.|.:..:       |.|:|:|.|
Zfish  2641 DSTDTDKHKKKKRKKLEGQENVEADVA-----DVHSAEPDQFSELQIPE-------MTTKKKKKH 2693

  Fly  2745 SRKMEGISLESNLAARRQKLQRGDALRNDSTPDDENSLLVSGVKAHKNAKTQRSKTVGEAKSSAD 2809
            .|.:|...|:...:....|..:.:.|.:..|.::..      :|..|..|.:|..|......|.|
Zfish  2694 KRCVEESGLKDISSNEAFKALQTNQLEHIETSEEMT------IKTVKKKKKKRDATEEPHYKSLD 2752

  Fly  2810 MELRWLKMRQNSMPVQIDCEVFRVIPKHMRKRIKS-------AEANKRK 2851
            :::         .|.:...|......||.:||.:|       .||.:||
Zfish  2753 LDV---------SPTESTTEAKLNPTKHKKKRKQSFSGCHDAQEAPERK 2792

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14692	NP_650019.6	DD_R_PKA	9..43	CDD:295380
		DD_R_PKA	82..120	CDD:295380	8/50 (16%)
		LRIF1	<1113..1428	CDD:292369	80/368 (22%)
pho	NP_001002867.3	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000