Protein Alignment Mcm5 and yifB

DIOPT Version :10

• Sequence 1: NP_524308.2
• Gene: Mcm5 / 41296
• FlyBaseID: FBgn0017577
• Length: 733
• Species: Drosophila melanogaster
• Sequence 2: NP_418214.2
• Gene: yifB / 948282
• ECOCYCID: EG11260
• Length: 506
• Species: Escherichia coli
• Alignment Length: 567
• Identity: 109/567 - (19%)
• Similarity: 189/567 - (33%)
• Gaps: 165/567 - (29%)

  Fly   152 AASGISAKATRMSIQCLSCSTVIPNL---------------KVNPGL--EGYALPRKCNT----- 194
            ||.|::|....:.:.   .|..:|.|               :|...:  .||..|.|..|
E. coli    10 AALGVNAPPITVEVH---ISKGLPGLTMVGLPETTVKEARDRVRSAIINSGYEYPAKKITINLAP 71

  Fly   195 ----EQAGRPKCPLDPFFIMPDKCKCVDFQTLKLQELPDFVPQGEIPRHLQLFCDRSLCERVVPG 255
                ::.||...|:....:...       :.|...:|.::...||:.....|        |.|||
E. coli    72 ADLPKEGGRYDLPIAIALLAAS-------EQLTANKLDEYELVGELALTGAL--------RGVPG 121

  Fly   256 NRVLIQGIYSIRKVGKPSRRDGREKAVVGVRAPYMRVVGITVDSEG-AGAISRYSNITSD----- 314
                  .|.|..:..|..|:                 :.:..|:|. .|.|:....:.:|
E. coli   122 ------AISSATEAIKSGRK-----------------IIVAKDNEDEVGLINGEGCLIADHLQAV 163

  Fly   315 ----EEEHFRRMAASGDIYERLSQSLAPSIFGSRDIKKAITCMLFGGSRKRLPDGLCRRGDINVL 375
                |.:|........|...|..|.....:.|....|:.:.....||.              |:|
E. coli   164 CAFLEGKHALERPKPTDAVSRALQHDLSDVIGQEQGKRGLEITAAGGH--------------NLL 214

  Fly   376 LLGDPGTAKSQLLKFVEKVAPIAVYTSGKGSSAAGLT----ASVMKDPQTRNF----------VM 426
            |:|.|||.|:.|...:..:.| .:.......|||.|:    .||.|..:.|.|          .|
E. coli   215 LIGPPGTGKTMLASRINGLLP-DLSNEEALESAAILSLVNAESVQKQWRQRPFRSPHHSASLTAM 278

  Fly   427 EGGAMV-------LADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAA 484
            .||..:       ||..||:.:||..:.......|:.|.:|...|.:::.....|..:|..::||
E. coli   279 VGGGAIPGPGEISLAHNGVLFLDELPEFERRTLDALREPIESGQIHLSRTRAKITYPARFQLVAA 343

  Fly   485 AN-SIFGRWDDTKG----EENIDFMPTI----LSRFDMIFIVKDIHDESRDITLAKHIINVHLSS 540
            .| |..|.:.....    |:.:.::..:    |.|||:          |.:|.|..    ..:.|
E. coli   344 MNPSPTGHYQGNHNRCTPEQTLRYLNRLSGPFLDRFDL----------SLEIPLPP----PGILS 394

  Fly   541 NKSAPSEPAEGEISLSTFKKYIHYCRTH------------CGPRLSEAAGEKLKSRYVLMRSGAG 593
            ....|.|      |.:|.|:.:...|..            ..|.:.:..  ||:|...:...|.
E. coli   395 KTVVPGE------SSATVKQRVMAARERQFKRQNKLNAWLDSPEIRQFC--KLESEDAMWLEGT- 450

  Fly   594 QQEKASDKRLSIPITVRQLEAVIRISESLAKIRLQPFATDEHVNEAL 640
                    .:.:.:::|..:.:::::.::|.|......|.:|:.||:
E. coli   451 --------LIHLGLSIRAWQRLLKVARTIADIDQSDIITRQHLQEAV 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm5	NP_524308.2	MCM_N	31..125	CDD:464206
		MCM	128..648	CDD:214631	109/567 (19%)
yifB	NP_418214.2	PRK09862	1..506	CDD:182120	109/567 (19%)