Protein Alignment Mcm5 and PRL

DIOPT Version :10

• Sequence 1: NP_524308.2
• Gene: Mcm5 / 41296
• FlyBaseID: FBgn0017577
• Length: 733
• Species: Drosophila melanogaster
• Sequence 2: NP_192115.1
• Gene: PRL / 828153
• AraportID: AT4G02060
• Length: 716
• Species: Arabidopsis thaliana
• Alignment Length: 745
• Identity: 251/745 - (33%)
• Similarity: 367/745 - (49%)
• Gaps: 115/745 - (15%)

  Fly    14 NFGGDNQQDAQINLQAVKKKYKEFIRTFNEENFFYKYRDTLKRNYLNGRYF--LEIEMEDLVGF- 75
            :|.||            |...|.|:..|.:.|...||.:.|:.  ::.|..  ::::::||..:
plant     5 DFDGD------------KGLAKGFLENFADANGRSKYMEILQE--VSNRKIRAIQVDLDDLFNYK 55

  Fly    76 --DETLADKLNKQPTEHLEIFEEAAREVADEITA--PRPEHE----------------------- 113
              .|....:|.:....::.||..|..|:..|.|.  |..:|:
plant    56 DESEEFLGRLTENTRRYVSIFSAAVDELLPEPTEAFPDDDHDILMTQRADDGTDNPDVSDPHQQI 120

  Fly   114 ----EHMHDIQILLSSNANPTNIRQLKSDCVSKLVKIAGIIVAASGISAKATRMSIQCLSCSTVI 174
                :..:::.....|...|:.||::|:..:.:||:|:||:...|.:..........|..|
plant   121 PSEIKRYYEVYFKAPSKGRPSTIREVKASHIGQLVRISGIVTRCSDVKPLMAVAVYTCEDC---- 181

  Fly   175 PNLKVNPGLEGYA-------LPR-KCNT------EQAGRPKCPLDPFFIMPDKCKCVDFQTLKLQ 225
                   |.|.|.       :|. ||.:      .:||.|       .:.....|.:.||..|:|
plant   182 -------GHEIYQEVTSRVFMPLFKCPSSRCRLNSKAGNP-------ILQLRASKFLKFQEAKMQ 232

  Fly   226 ELPDFVPQGEIPRHLQLFCDRSLCERVVPGNRVLIQGIY-SIRKVGKPSRRDGREKAVVGVRAPY 289
            ||.:.||:|.|||.:.:.....|..:|.||:.|...||: .|...|..:.|.|.      |...|
plant   233 ELAEHVPKGHIPRSMTVHLRGELTRKVSPGDVVEFSGIFLPIPYTGFKALRAGL------VADTY 291

  Fly   290 MRVVGITVDSEGAGAISRYS--NITSDEEEHFRRMAASGDIYERLSQSLAPSIFGSRDIKKAITC 352
            :....:|...:      :|.  ....||||...|:|..||||.:||:||||.|:|..|||||:..
plant   292 LEATSVTHFKK------KYEEYEFQKDEEEQIARLAEDGDIYNKLSRSLAPEIYGHEDIKKALLL 350

  Fly   353 MLFGGSRKRLPDGLCRRGDINVLLLGDPGTAKSQLLKFVEKVAPIAVYTSGKGSSAAGLTASVMK 417
            :|.|...::|.||:..|||:::.|:||||.|||||||.:..|||..|||:|||||..||||:||:
plant   351 LLVGAPHRQLKDGMKIRGDVHICLMGDPGVAKSQLLKHIINVAPRGVYTTGKGSSGVGLTAAVMR 415

  Fly   418 DPQTRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVL 482
            |..|...|:||||:||||.|:..|||||||.|.||.||||.|||||:|||||||||:||:|.:||
plant   416 DQVTNEMVLEGGALVLADMGICAIDEFDKMDESDRTAIHEVMEQQTVSIAKAGITTSLNARTAVL 480

  Fly   483 AAANSIFGRWDDTK-GEENIDFMPTILSRFDMIFIVKDIHDESRDITLAKHIINVHLSSNKSAPS 546
            ||||..:||:|..: ..|||:..|.:|||||:::::.|..|...|:.||||:::||.:....|..
plant   481 AAANPAWGRYDLRRTPAENINLPPALLSRFDLLWLILDRADMDSDLELAKHVLHVHQTEESPALG 545

  Fly   547 -EPAEGEISLSTFKKYIHYCRTHCGPRLSEAAGEKLKSRYVLMRSGAGQQEKASDKRLSIPITVR 610
             ||.|..|    .:.||...|     |||.....:|: .|:.....:.:||:|.........|||
plant   546 FEPLEPNI----LRAYISAAR-----RLSPYVPAELE-EYIATAYSSIRQEEAKSNTPHSYTTVR 600

  Fly   611 QLEAVIRISESLAKIRLQPFATDEHVNEALRLFQVSTLDA-AMTGSLAGAEGFTTEEDQETLNRI 674
            .|.:::|||.:||::|.........|:|||||.|:|.:.. |.....||.:..:   |..::.|.
plant   601 TLLSILRISAALARLRFSESVAQSDVDEALRLMQMSKISLYADDRQKAGLDAIS---DTYSIIRD 662

  Fly   675 EKQLKRRFAIGSQVSEQNILQDFLRQKYEE 704
            |....::    :.||..|.|....|:.|.|
plant   663 EAARSKK----THVSYANALNWISRKGYSE 688

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm5	NP_524308.2	MCM_N	31..125	CDD:464206	21/127 (17%)
		MCM	128..648	CDD:214631	213/538 (40%)
PRL	NP_192115.1	MCM_N	16..96	CDD:464206	18/81 (22%)
		MCM	139..638	CDD:214631	213/538 (40%)