Protein Alignment Mcm5 and MCM9

DIOPT Version :10

• Sequence 1: NP_524308.2
• Gene: Mcm5 / 41296
• FlyBaseID: FBgn0017577
• Length: 733
• Species: Drosophila melanogaster
• Sequence 2: NP_001318221.1
• Gene: MCM9 / 815890
• AraportID: AT2G14050
• Length: 651
• Species: Arabidopsis thaliana
• Alignment Length: 689
• Identity: 194/689 - (28%)
• Similarity: 318/689 - (46%)
• Gaps: 112/689 - (16%)

  Fly    36 EFIRTFNEENFFYK-YRDTLKRNYLNG----RYFLEIEMEDLVGFDETLADKLNKQPTEHLEIFE 95
            |.|.:..|  |..| |.|.|:...|:.    .|.|.||..:||..:.:||.::...|..:|..|:
plant     9 EHIESMTE--FLVKHYPDQLREISLSSDPKLHYPLFIEYAELVDDNPSLARQVFSDPEHYLRQFD 71

  Fly    96 EAAREVADEITAPRPEHEEHMHD--------IQILLSSNANPTNIRQLKSDCVSKL-VKIAGIIV 151
            ::| .:|.:|..   ||.:...:        |.:.::::.:|..........:.:: ||..||::
plant    72 DSA-ILAHKIAL---EHMKKFEEKIGIEKRFIHVRINTSGSPLERSPETFPSIGRVRVKHRGILM 132

  Fly   152 AASG--ISAKATRM-----SIQCLSCSTVIPNLKVNPGLEGYALPRKCNTEQAGRPKCPLDPFFI 209
            ...|  |.:.|.:|     ..:|..|..:.|.......:.....|..|.::::  ..|....|..
plant   133 MLKGTVIRSGAVKMYEGEKMYRCRKCKHMFPIFPELESINSIVKPPFCPSQRS--KACEGTNFDP 195

  Fly   210 MPDKCKCVDFQTLKLQELPDFVPQGEIPRHLQLFCDRSLCERVVPGNRVLIQGIYSIR------- 267
            :.|.....|:|.:|:||....:..|.|||.:.:.....|.:.|..|:.|::.||.:.:
plant   196 VDDTVTRHDYQEIKIQENTQVLGVGVIPRSILVVLKDDLVDNVKAGDDVVVSGILTSKWSHDLKD 260

  Fly   268 --------KVGKPSRRDGREKAVVGVRAPYMRVVGITVDSEGAGAISRYSNITSDEEEHFRRMAA 324
                    .:....||....|:.:.:               ....|.::.|..|    |||....
plant   261 VRCDLEPMLIANHVRRTNELKSEIDI---------------SDDLIEKFKNFWS----HFRDTPL 306

  Fly   325 SGDIYERLSQSLAPSIFGSRDIKKAITCMLFGGSRKRLPDGLCRRGDINVLLLGDPGTAKSQLLK 389
            .|  ...:.:.:.|.:||...:|.|:...|.||.:.....|...||:.::||:|||||.|||.||
plant   307 KG--RNAILRGICPQVFGLFTVKLAVALTLIGGVQHVDASGTKVRGESHLLLIGDPGTGKSQFLK 369

  Fly   390 FVEKVAPIAVYTSGKGSSAAGLTASVMKDPQTRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVA 454
            |..|::..||.|:|.||::||||.:.:||  ...:::|.||:||||||:.||||||.|||.||..
plant   370 FAAKLSNRAVITTGLGSTSAGLTVTAVKD--GGEWMLEAGALVLADGGLCCIDEFDSMREHDRAT 432

  Fly   455 IHEAMEQQTISIAKAGITTTLNSRCSVLAAANSIFGRWD-DTKGEENIDFMPTILSRFDMIFIVK 518
            ||||||||:||:||||:.|||:::..|..|.|. .|::| |.....|......:|||||::.::.
plant   433 IHEAMEQQSISVAKAGLVTTLSTKTIVFGATNP-KGQYDPDQSLSVNTALSGPLLSRFDIVLVLL 496

  Fly   519 DIHDESRDITLAKHII-NVHLSSNKSAPSEPAEGEIS-------LSTFKKYIHYCRTHCGPRLSE 575
            |..:...|..::.||: .|.:..::         |:.       |...::||.:.:.:..|.||:
plant   497 DTKNPEWDAVVSSHILAEVQIEQDR---------EVDDLTTIWPLPMLQRYIQFVKKNFRPVLSK 552

  Fly   576 AAGEKLKSRYVLMRSGAGQQEKASDKRLSIPITVRQLEAVIRISESLAKIRLQPFATDEHVNEAL 640
            .|.|.:.|.|.|.|        .|....:...|||.||::||::::.|::..:        ||..
plant   553 EAEEIISSYYRLQR--------RSSTHNAARTTVRMLESLIRLAQAHARLMFR--------NEVT 601

  Fly   641 RLFQVST---LDAAMT-----GSLAGA--EGFTTEEDQE 669
            ||..::.   ::::||     .|:..|  ..|:.|.|||
plant   602 RLDAITAILCIESSMTISAIVDSMGNALHSNFSEEPDQE 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm5	NP_524308.2	MCM_N	31..125	CDD:464206	26/101 (26%)
		MCM	128..648	CDD:214631	159/554 (29%)
MCM9	NP_001318221.1	Mcm2	6..616	CDD:440854	185/663 (28%)
		MCM9	311..615	CDD:350666	117/331 (35%)