Protein Alignment Mcm5 and mcm5

DIOPT Version :10

• Sequence 1: NP_524308.2
• Gene: Mcm5 / 41296
• FlyBaseID: FBgn0017577
• Length: 733
• Species: Drosophila melanogaster
• Sequence 2: NP_001017327.2
• Gene: mcm5 / 550081
• XenbaseID: XB-GENE-985665
• Length: 735
• Species: Xenopus tropicalis
• Alignment Length: 738
• Identity: 521/738 - (70%)
• Similarity: 619/738 - (83%)
• Gaps: 10/738 - (1%)

  Fly     1 MEGFDDAGVFFSDNFGGDNQ--QDAQINLQAVKKKYKEFIRTF----NEENFFYKYRDTLKRNYL 59
            |.||||.|:::||:|||:..  .|.|.....:||:::||:|.:    :...|.:||||.|||:|.
 Frog     1 MSGFDDLGIYYSDSFGGEQPVGDDGQAKKSQLKKRFREFLRQYRVGTDRTGFTFKYRDELKRHYN 65

  Fly    60 NGRYFLEIEMEDLVGFDETLADKLNKQPTEHLEIFEEAAREVADEITAPRPEHEEHMHDIQILLS 124
            .|.|::|:|||||..|||.|||.|.|||||||::.||||:|||||:|.|||..||.:.:||::|.
 Frog    66 LGEYWIEVEMEDLASFDEDLADYLYKQPTEHLQLLEEAAQEVADEVTRPRPAGEETIQEIQVMLR 130

  Fly   125 SNANPTNIRQLKSDCVSKLVKIAGIIVAASGISAKATRMSIQCLSCSTVIPNLKVNPGLEGYALP 189
            |:|||.|||.|||:.:|.||||.|||:||:.:.||||::||||.||...|.|:.|.|||||||:|
 Frog   131 SDANPANIRSLKSEQMSHLVKIPGIIIAATAVRAKATKISIQCRSCRNTIGNIAVRPGLEGYAMP 195

  Fly   190 RKCNTEQAGRPKCPLDPFFIMPDKCKCVDFQTLKLQELPDFVPQGEIPRHLQLFCDRSLCERVVP 254
            |||||||||||||||||:||:||||||||||||||||.||.||.||:|||:||:|||.||::|||
 Frog   196 RKCNTEQAGRPKCPLDPYFIIPDKCKCVDFQTLKLQESPDAVPHGELPRHMQLYCDRYLCDKVVP 260

  Fly   255 GNRVLIQGIYSIRKVGKPSRRDGREKAVVGVRAPYMRVVGITVDSEGAGAISRYSNITSDEEEHF 319
            ||||.|.|||||||.||.|.: ||::..||:|:.|:|||||.||:||.|. |....||..|||.|
 Frog   261 GNRVTIMGIYSIRKSGKTSTK-GRDRVGVGIRSSYIRVVGIQVDTEGTGR-SAAGAITPQEEEEF 323

  Fly   320 RRMAASGDIYERLSQSLAPSIFGSRDIKKAITCMLFGGSRKRLPDGLCRRGDINVLLLGDPGTAK 384
            ||::|..||||.:::|:||||:||.||||||.|:|||||||||||||.||||:|:|:||||||||
 Frog   324 RRLSAKPDIYETVAKSIAPSIYGSSDIKKAIACLLFGGSRKRLPDGLTRRGDVNLLMLGDPGTAK 388

  Fly   385 SQLLKFVEKVAPIAVYTSGKGSSAAGLTASVMKDPQTRNFVMEGGAMVLADGGVVCIDEFDKMRE 449
            ||||||||:.:||.||||||||||||||||||:||.:|||:||||||||||||||||||||||||
 Frog   389 SQLLKFVERCSPIGVYTSGKGSSAAGLTASVMRDPVSRNFIMEGGAMVLADGGVVCIDEFDKMRE 453

  Fly   450 DDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSIFGRWDDTKGEENIDFMPTILSRFDMI 514
            ||||||||||||||||||||||||||||||||||||||::|||||||||||||||||||||||||
 Frog   454 DDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVYGRWDDTKGEENIDFMPTILSRFDMI 518

  Fly   515 FIVKDIHDESRDITLAKHIINVHLSSNKSAPSEPAEGEISLSTFKKYIHYCRTHCGPRLSEAAGE 579
            |||||.|:|.||:|||||::|||||:...:.|  .||||.|:|.||||.|||..||||||..:.|
 Frog   519 FIVKDEHNEQRDMTLAKHVMNVHLSARTQSSS--VEGEIDLNTLKKYIAYCRAKCGPRLSAESAE 581

  Fly   580 KLKSRYVLMRSGAGQQEKASDKRLSIPITVRQLEAVIRISESLAKIRLQPFATDEHVNEALRLFQ 644
            |||:||:||||||...|:.::||.|||||||||||::||||||.|::||||||:..|.|||||||
 Frog   582 KLKNRYILMRSGARDHERETEKRSSIPITVRQLEAIVRISESLGKMKLQPFATETDVEEALRLFQ 646

  Fly   645 VSTLDAAMTGSLAGAEGFTTEEDQETLNRIEKQLKRRFAIGSQVSEQNILQDFLRQKYEERTVMK 709
            ||||||||:|||:|.|||||:||||.|:||||||||||||||||||.:|:||||:|||.|..:.|
 Frog   647 VSTLDAAMSGSLSGVEGFTTQEDQEMLSRIEKQLKRRFAIGSQVSEHSIIQDFLKQKYPEHAIHK 711

  Fly   710 VIHTMIRRGELQHRMQRKMLYRI 732
            |:|.|:||||:|||:|||:||||
 Frog   712 VLHLMMRRGEIQHRLQRKVLYRI 734

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm5	NP_524308.2	MCM_N	31..125	CDD:464206	54/97 (56%)
		MCM	128..648	CDD:214631	387/519 (75%)
mcm5	NP_001017327.2	MCM_N	33..131	CDD:464206	54/97 (56%)
		MCM	134..650	CDD:214631	387/519 (75%)
		Arginine finger	513..516		2/2 (100%)