Protein Alignment Mcm5 and mcm7

DIOPT Version :10

• Sequence 1: NP_524308.2
• Gene: Mcm5 / 41296
• FlyBaseID: FBgn0017577
• Length: 733
• Species: Drosophila melanogaster
• Sequence 2: NP_998877.1
• Gene: mcm7 / 407945
• XenbaseID: XB-GENE-5946446
• Length: 720
• Species: Xenopus tropicalis
• Alignment Length: 768
• Identity: 251/768 - (32%)
• Similarity: 384/768 - (50%)
• Gaps: 148/768 - (19%)

  Fly    28 QAVKKKYKEFIRTFNEENFFYKYRDTLKRNYLNG----------RYFLEIEMEDLVGFDETLADK 82
            ||.|:|.|.|::.      |||..:..|:|:..|          :..|.|:::||...|..|.|.
 Frog     6 QAEKEKCKTFLQE------FYKDDELGKKNFKYGVQLANIAHREQVALYIDLDDLAEEDPELVDA 64

  Fly    83 LNKQPTEHLEIFEEAAREVADEITAPRPEHEEHMH----DIQI---LL--------SSNANPTN- 131
            :.:....:..:|.:|.:|:     .|:.:..|.:|    |:.|   |:        |...:|.|
 Frog    65 ICENTRRYTNLFADAVQEL-----LPQYKEREVVHKDALDVYIEHRLMMEQRGRDPSETRDPHNQ 124

  Fly   132 -----------------------IRQLKSDCVSKLVKIAGIIVAASGISAKATRMSIQCLSCSTV 173
                                   :|.:|:|.:.|||.:.||:...:.:.......:..|..|
 Frog   125 YPPELMRRFELYFKAPSSSKARVVRDVKADSIGKLVTVRGIVTRVTEVKPMMVVATYTCDQC--- 186

  Fly   174 IPNLKVNPGLEGYA-------LP------RKCNTEQAGRPKCPLDPFFIMPDKCKCVDFQTLKLQ 225
                    |.|.|.       :|      |:|.|.::|      ...::.....|.:.||.||:|
 Frog   187 --------GAETYQPIQSPTFMPLIMCPSRECQTNRSG------GRLYLQTRGSKFIKFQELKIQ 237

  Fly   226 ELPDFVPQGEIPRHLQLFCDRSLCERVVPGNRVLIQGIYSIRKVGKPSRRDGREKAVVGVRA-PY 289
            |..|.||.|.|||.:.::..........||:.|.|.|::      .|..|.|..:.|.|:.: .|
 Frog   238 EHSDQVPVGNIPRCMSVYVRGENTRLAQPGDHVSITGVF------LPMLRTGFRQVVQGLLSETY 296

  Fly   290 M---RVVGI--TVDSE-GAGAISRYSNITSDEEEHFRRMAASGDIYERLSQSLAPSIFGSRDIKK 348
            :   |:|.:  |.|.| |...:|         ||..|::... |.||:|:.|:||.|:|..|:||
 Frog   297 LESHRLVKMNKTEDDELGTEELS---------EEELRQITEE-DFYEKLAASIAPEIYGHEDVKK 351

  Fly   349 AITCMLFGGSRKRLPDGLCRRGDINVLLLGDPGTAKSQLLKFVEKVAPIAVYTSGKGSSAAGLTA 413
            |:..:|.||. ...|.|:..||:||:.|:||||.||||||.:::::||.:.||:|:|||..||||
 Frog   352 ALLLLLVGGV-DNSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTA 415

  Fly   414 SVMKDPQTRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSR 478
            :|||||.|....:||||:||||.||.||||||||.:.||.||||.|||||||||||||.||||:|
 Frog   416 AVMKDPVTGEMTLEGGALVLADQGVCCIDEFDKMMDTDRTAIHEVMEQQTISIAKAGIMTTLNAR 480

  Fly   479 CSVLAAANSIFGRWDDTKG-EENIDFMPTILSRFDMIFIVKDIHDESRDITLAKHIINVHLSSNK 542
            ||:|||||..:||::..|. |:||.....:|||||::::::|..|...|:.||:||..||..| |
 Frog   481 CSILAAANPAYGRYNPKKTVEQNIQLPAALLSRFDLLWLIQDKPDRDNDLRLAQHITYVHQHS-K 544

  Fly   543 SAPS--EPAEGEISLSTFKKYIHYCRTHCGPRLSEAAGEKLKSRYVLMRSGAGQQEKASDKRLSI 605
            ..||  :|    :.:...::||..|:.. .|.:.|:..:.|.:.||.||     :|..::|.::.
 Frog   545 QPPSQFQP----LDMKLMRRYITMCKRK-QPAIPESLADYLTAAYVEMR-----KEARTNKDMTF 599

  Fly   606 PITVRQLEAVIRISESLAKIRLQPFATDEHVNEALRLFQVSTLDAAMTGSLAGAEGFTTEEDQ-- 668
             .:.|.|.:::|:|.:||::||:.....|.||||:||.::|      ..||.|.:|.|:...:
 Frog   600 -TSARTLLSILRLSTALARLRLEDVVEKEDVNEAMRLTEMS------KDSLLGDKGQTSRTQRPA 657

  Fly   669 ----ETLNRIEKQLKRRFAIGSQVSEQNILQDF-------LRQKYEERTVMKV 710
                .|:..:..:...|....|:..::.:.:.|       ..::|||..|..|
 Frog   658 DVIFSTIREMVPEKGARSVKYSEAEQRAVSKGFTPAQFEAALEEYEELNVWLV 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm5	NP_524308.2	MCM_N	31..125	CDD:464206	26/118 (22%)
		MCM	128..648	CDD:214631	208/566 (37%)
mcm7	NP_998877.1	MCM_N	9..102	CDD:464206	24/103 (23%)
		MCM	144..640	CDD:214631	206/547 (38%)
		Arginine finger	512..515		2/2 (100%)