Protein Alignment Mcm5 and LOC3290529

DIOPT Version :10

• Sequence 1: NP_524308.2
• Gene: Mcm5 / 41296
• FlyBaseID: FBgn0017577
• Length: 733
• Species: Drosophila melanogaster
• Sequence 2: XP_061502321.1
• Gene: LOC3290529 / 3290529
• VectorBaseID: AGAMI1_014641
• Length: 1119
• Species: Anopheles gambiae
• Alignment Length: 752
• Identity: 212/752 - (28%)
• Similarity: 322/752 - (42%)
• Gaps: 156/752 - (20%)

  Fly    58 YLNGRYFLEI-----EMEDL--VGFDETLADKLNKQPTEHLEIFEEAAREVA------------- 102
            ||...|..||     ..:||  |.....|.....:||.....||::...|:|
Mosquito     4 YLKKHYAQEITDLLNNSDDLQHVSIHVNLTQLQREQPQLFARIFQDTQTELARWNECLLRAQKSL 68

  Fly   103 ---DEITAPRPEHEEHMH----DIQIL---LSSNANPTNIRQLKSDCVSKLVKIAGIIVAASGIS 157
               :....|..:.:|:.|    ::.:.   |..:|.|.|      |.|.:.:::.|.::..|...
Mosquito    69 IEGNLFLDPGFQVKENCHVRFVNVPVSPAELRKSAYPNN------DSVGQFLQVKGSVIRMSSSR 127

  Fly   158 AKATRMSIQCLSCSTVIPNLKVNPGLEG-------YALPRKC-NTEQAGRPKC--PLDPFFIMPD 212
            ....|....|..|       |....:|.       :..|..| |..:||   |  .|.|....|.
Mosquito   128 FLEYRREYACTRC-------KQKVVIEAEYCKSYVFEPPGPCPNAREAG---CRGQLQPVSAQPQ 182

  Fly   213 KCKCVDFQTLKLQELPDFVPQGEIPRHLQLFCDRSLCERVVPGNRVLIQGIYSIRKVGKPSRRDG 277
            ...|.|:|.:::||:   :.:..:|..|.:..:..|.:...||:.|.:.|  .|....||.....
Mosquito   183 PELCRDYQEIRIQEI---MSERNVPASLVVTLEDDLVDSCQPGDCVTVCG--PIEHRWKPPTVGR 242

  Fly   278 REKAVVGVRAPYMRVVGITVDSEGAGAISRYSNITS---DEEEHFRRMAAS--------GDIYER 331
            |.:..:.:|               |.:::|..:..|   |..||...:.|.        |::..|
Mosquito   243 RTEVTIAMR---------------ANSVAREESKASWAKDLPEHLLCVPAEWQEVLREIGELAAR 292

  Fly   332 --LSQSLAPSIFGSRDIKKAITCMLFGGSRKRLPDG---LCRRGDINVLLLGDPGTAKSQLLKFV 391
              |.||:||:|.|...:|.||...| ....:|:.||   ...||..::||:||||.|||||||:.
Mosquito   293 DLLVQSIAPAIRGMYPVKLAIALAL-ASCTERVGDGEQQATVRGHSHLLLVGDPGLAKSQLLKYA 356

  Fly   392 EKVAPIAVYTSGKGSSAAGLTASVMKDPQTRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIH 456
            .::|..||||:|.|.|:|||||:.:||  ...:.:|.||:||||||:.|||||:.|||.|:.:||
Mosquito   357 SEIASRAVYTTGMGCSSAGLTAAAVKD--EGEWQLEAGALVLADGGICCIDEFNLMRETDKASIH 419

  Fly   457 EAMEQQTISIAKAGITTTLNSRCSVLAAAN--SIFGRWDDT-KGEENIDFMPTILSRFDMIFIVK 518
            |||||||||:||||:...|::||.||||.|  :::...|.. |..|||.....:||||||:.|:|
Mosquito   420 EAMEQQTISVAKAGMVCKLSTRCVVLAATNPKNLYTMSDGLGKSAENIGIGGPLLSRFDMVMILK 484

  Fly   519 DIHDESRDITLAKHIINVHLSSNKSAPSEPAEGE-------ISLSTFKKYIHYCRT---HCGPRL 573
            |:.....|..:|.|::...|...:   .|..|||       ......|..:|:...   |  ||:
Mosquito   485 DVRAADWDADIANHLLAQALLDEE---RECFEGEGNRTDRVAHWELEKLQLHFAAIKDFH--PRV 544

  Fly   574 SEAAGEKLKSRYVLMRSGAGQQEKASDKRLSIPITVRQLEAVIRISESLAKIRLQPFATDEHVNE 638
            |..|...|.:.|...||...:....:        |||.|:::.|::::.|::.|:...|......
Mosquito   545 SPEANVILGAYYKACRSDPYRDPTRT--------TVRLLDSLFRLAQAHARLLLRNEVTPIDAIT 601

  Fly   639 ALRLFQVS---------TLDAAMTGSLAGAEGFTTEEDQETLNRIEKQLKRRFAIGSQVSEQNIL 694
            .::|.:.|         |.|........|.|..|.:...:.||.                 ..::
Mosquito   602 IIQLMEASWGFGKIGIPTYDLIKAQLPLGPEQGTIDRLLDVLNL-----------------HGVV 649

  Fly   695 QDFLRQKYEERTVMKVIHTMIRR--GELQHRMQRKML 729
            ||       ..||..:...::||  .||..:.:||.|
Mosquito   650 QD-------TATVRPIDPNILRRYHRELIEKQKRKQL 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm5	NP_524308.2	MCM_N	31..125	CDD:464206	19/96 (20%)
		MCM	128..648	CDD:214631	174/567 (31%)
LOC3290529	XP_061502321.1	None