Protein Alignment Mcm5 and mcm5

DIOPT Version :9

• Sequence 1: NP_524308.2
• Gene: Mcm5 / 41296
• FlyBaseID: FBgn0017577
• Length: 733
• Species: Drosophila melanogaster
• Sequence 2: NP_001342928.1
• Gene: mcm5 / 2542477
• PomBaseID: SPAC1B2.05
• Length: 720
• Species: Schizosaccharomyces pombe
• Alignment Length: 736
• Identity: 346/736 - (47%)
• Similarity: 479/736 - (65%)
• Gaps: 31/736 - (4%)

  Fly     3 GFDDAGVFFSDNFGGDNQQDAQINLQAVKKKYKEFIRTFNEENFFYKYRDTLKRNYLNGRYFLEI 67
            |::.:.|:::....|:.:.|:.::.:   |.:.:||..|..:|.|. ||..|:.|.:..:|.|.|
pombe     6 GWERSAVYYTPVLPGEQELDSNVSHE---KNFIQFIEEFVIDNDFI-YRTQLRDNLVVKQYMLNI 66

  Fly    68 EMEDLVGFDETLADKLNKQPTEHLEIFEEAAREVADEITAPRPEH-EEHMHDIQILLSSNANPTN 131
            ::..|:.::|.||..|..|||:.|.:||.|...||..:.....|: ..::...|:.|..:||...
pombe    67 DLRHLISYNEDLAHLLLSQPTDILPLFESAVTTVAKRLLYRSQENASTNIPTCQVTLRYDANILP 131

  Fly   132 IRQLKSDCVSKLVKIAGIIVAASGISAKATRMSIQCLSC-STVIPNLKVNPGLEGYALPRKCNTE 195
            ||.|.:..:||||::.|||:.||.:|.:||.:.:.|.:| :|.|  |:::.|..|..|||.|...
pombe   132 IRNLTASHISKLVRVPGIIIGASTLSCRATALHLVCRNCRATRI--LQISGGFSGVQLPRVCEAP 194

  Fly   196 --QAGRPKCPLDPFFIMPDKCKCVDFQTLKLQELPDFVPQGEIPRHLQLFCDRSLCERVVPGNRV 258
              ...:..||:|||.|...|...:|.|.|||||.||.||.||:|||:.|..||.|..::.||.|.
pombe   195 VLDGEKKDCPMDPFIIDHSKSTFIDQQVLKLQEAPDMVPVGELPRHILLNADRYLTNQITPGTRC 259

  Fly   259 LIQGIYSIRKVGKPSRRDGREKAVVGVRAPYMRVVGITVDS-EGAGAISRYSNITSDEEEHFRRM 322
            :|.||:||.:     .:..:....|.:|.||:|||||.:|| :|:.:...:|   .:|||.|..:
pombe   260 VITGIFSIFQ-----NKSVKASGAVAIRNPYIRVVGIQMDSNDGSKSTPLFS---EEEEEEFLEI 316

  Fly   323 AASGDIYERLSQSLAPSIFGSRDIKKAITCMLFGGSRKRLPDGLCRRGDINVLLLGDPGTAKSQL 387
            :.:.::|:.:|.|::|:|:|:.||||||.|:||.||:|.||||:..||||||||||||||||||.
pombe   317 SRTPNLYDIISNSISPAIYGNVDIKKAIACLLFSGSKKILPDGMRLRGDINVLLLGDPGTAKSQF 381

  Fly   388 LKFVEKVAPIAVYTSGKGSSAAGLTASVMKDPQTRNFVMEGGAMVLADGGVVCIDEFDKMREDDR 452
            |||||::||||||||||||||||||||:.:|..||.|.:|||||||||||:||||||||||::||
pombe   382 LKFVERLAPIAVYTSGKGSSAAGLTASIQRDSVTREFYLEGGAMVLADGGIVCIDEFDKMRDEDR 446

  Fly   453 VAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSIFGRWDDTKGE-ENIDFMPTILSRFDMIFI 516
            |||||||||||||||||||||.||||.|||||||.||||:||.|.. |||||..|||||||||||
pombe   447 VAIHEAMEQQTISIAKAGITTILNSRTSVLAAANPIFGRYDDMKTPGENIDFQSTILSRFDMIFI 511

  Fly   517 VKDIHDESRDITLAKHIINVHLSSNKSAPSEPAEGEISLSTFKKYIHYCRTHCGPRLSEAAGEKL 581
            |||.|||::|..:|:|:||:|.:..:|:.: .|.|||....|::||:|||..|.|.|...|.|||
pombe   512 VKDEHDETKDRNIARHVINLHTNLQESSET-LAIGEIPFDKFRRYINYCRHKCAPNLDAEAAEKL 575

  Fly   582 KSRYVLMRSGAGQQEKASDKRLSIPITVRQLEAVIRISESLAKIRLQPFATDEHVNEALRLFQVS 646
            .|::|.:|....|.|:.|:.|.:||||||||||:|||:|||||:.|.|.|::.|..||:|||..|
pombe   576 SSQFVAIRKRVHQSEQDSNSRSTIPITVRQLEAIIRITESLAKMSLSPIASEAHATEAIRLFLTS 640

  Fly   647 TLDAAMTGSLAGAEGFTTEEDQETLNRIEKQLKRRFAIGSQVSEQNILQDFLR-QKYEERTVMKV 710
            ||.||...|         .|..|.:.:||..|::|..||.|.|.:.::::::. ..|.:..:...
pombe   641 TLAAATQSS---------PEVTEEVKKIEASLRKRLPIGFQASYRMLIREYVNGHGYSQHALEMA 696

  Fly   711 IHTMIRRGELQHRMQRKMLYR 731
            :..:..:..:|.|...:.:||
pombe   697 LQILSSKETIQLRNGGQTVYR 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm5	NP_524308.2	MCM_N	31..124	CDD:405270	29/93 (31%)
		MCM	128..648	CDD:214631	291/524 (56%)
mcm5	NP_001342928.1	MCM_N	34..124	CDD:317013	28/90 (31%)
		MCM	128..642	CDD:214631	291/524 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	324	1.000	Domainoid score	I221
eggNOG	1	0.900	-	-		E1_COG1241
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4904
Inparanoid	1	1.050	607	1.000	Inparanoid score	I158
OMA	1	1.010	-	-		QHG53983
OrthoFinder	1	1.000	-	-		FOG0004690
OrthoInspector	1	1.000	-	-		oto100578
orthoMCL	1	0.900	-	-		OOG6_102165
Panther	1	1.100	-	-	LDO	PTHR11630
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R695
SonicParanoid	1	1.000	-	-		X3292
TreeFam	1	0.960	-	-
	14	13.860