Protein Alignment Mcm5 and LOC1273388

DIOPT Version :10

• Sequence 1: NP_524308.2
• Gene: Mcm5 / 41296
• FlyBaseID: FBgn0017577
• Length: 733
• Species: Drosophila melanogaster
• Sequence 2: XP_312356.3
• Gene: LOC1273388 / 1273388
• VectorBaseID: AGAMI1_009590
• Length: 834
• Species: Anopheles gambiae
• Alignment Length: 638
• Identity: 190/638 - (29%)
• Similarity: 294/638 - (46%)
• Gaps: 97/638 - (15%)

  Fly   131 NIRQLKSDCVSKLVKIAGIIVAASGISAKATRMSIQCLSCSTVIPNLKVNPGLEGYALPRKCNTE 195
            :|..:|...:.|||.:.|.|:.|.......|..:.:|..|.:. ..::...|:  |..|..|::
Mosquito   215 SISSIKVSSMGKLVSVRGTIIRAGATQIMNTWCAFRCAQCGSE-QAVQQKDGI--YTTPTSCHS- 275

  Fly   196 QAGRPKCPLDPFFIMPDK---CKCVDFQTLKLQELP--DFVPQGEIPRHLQLFCDRSLCERVVPG 255
                 .|.....|::..:   .:...:|||:|||..  .....|...:::::.....|.:.|.||
Mosquito   276 -----GCKARSHFVLLQQSAFTRMEAYQTLRLQETTQGSRTVAGSAAKNIEIELTHELVDSVCPG 335

  Fly   256 NRVLIQGIYSIRKVGKPSRRDGREKAVVGVRAPYMRVVGITVDSEGAGAISRYSNITSDEEEHFR 320
            :.|.:.||...|   .....||..||  .:...|::.|.:..:.......:|.:..|..:.|..|
Mosquito   336 DDVTVTGILKAR---SQDGSDGAGKA--SMFKAYLQAVYVRSNKNVLANWNRLAEFTELDMEAIR 395

  Fly   321 RMAASGDIYERLSQSLAPSIFGSRDIKKAITCMLFGGSRKRLPDGLCRRGDINVLLLGDPGTAKS 385
            .:.|....:..|.|||.|:|:|...:|..:...||||    :.:....|.:|:||::||||..||
Mosquito   396 LIKAEPSPFRLLVQSLCPTIYGHEIVKAGLLLGLFGG----MANTARTRAEIHVLVVGDPGIGKS 456

  Fly   386 QLLKFVEKVAPIAVYTSGKGSSAAGLTASVMKDPQTRNFV---MEGGAMVLADGGVVCIDEFDKM 447
            |:|:....|:|..::..|..||..|||.:|    :|...|   :|.||:||||.||.||||||||
Mosquito   457 QILQSCANVSPRGIFVCGTNSSNVGLTVTV----RTEKGVGASLEAGALVLADQGVCCIDEFDKM 517

  Fly   448 REDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSIFGRWDDTKG-EENIDFMPTILSRF 511
              .....:.|.|||:::|:||||:..|:.:|.:||||||...|.::..|. .||:...|.:||||
Mosquito   518 --SGHSGLLEVMEQRSVSVAKAGVICTVPARTTVLAAANPAGGHYNKAKTVSENLKLHPALLSRF 580

  Fly   512 DMIFIVKDIHDESRDITLAKHIINVH------LSSNKSAPSEP-----------AEGEISL---- 555
            |::||:.|..:|..|..|..||..||      .|..:..||.|           .|||..|
Mosquito   581 DLVFILLDRSNERTDNLLTAHIQKVHGLAKAGSSHLQPQPSHPFFDASGHCSYEEEGEPPLEERL 645

  Fly   556 -------------STFKKYIHYCRTHCGPRLSEAAGEKLKSRYVLMRSGAGQQEKASDKRLSIPI 607
                         ...:|||.|.|.:..|:|:..|.|:|:..:|.:|       :|.:....||:
Mosquito   646 RLAPGEQMDLLPPEIVQKYIGYARKNVQPKLTAKAAEELREFFVELR-------RAHNHMDMIPV 703

  Fly   608 TVRQLEAVIRISESLAKIRLQPFATDEHVNEALRLFQVSTLDAAMTGSLAGAEGFTTEEDQETLN 672
            |.||||.:||::::.|||.|.|.||..||.:.|.:.:.|.||.           |:|:|......
Mosquito   704 TTRQLEGLIRLTQARAKIDLSPEATVAHVRDVLAILRQSMLDV-----------FSTDEGDLQFT 757

  Fly   673 RIEKQLKRRFAIGSQVSEQNILQDFLRQKYEERTVM-KVIHTMIRRGELQHRM 724
            |:..        ||..|:.::::.|.|.......|. ..::||   .||:..|
Mosquito   758 RLTN--------GSGTSKTSMVRKFARVLASRSAVTGTTLYTM---AELRQAM 799

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm5	NP_524308.2	MCM_N	31..125	CDD:464206
		MCM	128..648	CDD:214631	173/559 (31%)
LOC1273388	XP_312356.3	Mcm2	224..832	CDD:440854	188/629 (30%)