Protein Alignment Mcm5 and mcm9

DIOPT Version :10

• Sequence 1: NP_524308.2
• Gene: Mcm5 / 41296
• FlyBaseID: FBgn0017577
• Length: 733
• Species: Drosophila melanogaster
• Sequence 2: XP_002932153.1
• Gene: mcm9 / 100490403
• XenbaseID: XB-GENE-949288
• Length: 1126
• Species: Xenopus tropicalis
• Alignment Length: 703
• Identity: 201/703 - (28%)
• Similarity: 322/703 - (45%)
• Gaps: 100/703 - (14%)

  Fly    35 KEFIRTFNEENFFYKYRDTLKRNYLNGRYFLEIEMEDLVGFDETLADKLNKQPTEHLEIFEEAAR 99
            ||..:...|     ||.|......:|.....|..||        :.:..|..|.|.|.||:.|.|
 Frog    25 KEIAQILTE-----KYEDAHYSLVVNAMTLFEANME--------IGEYFNAFPNEVLPIFDNALR 76

  Fly   100 EVADEITAPRPEHEEHMHDIQILLSSNAN---------PTNIRQ--LKSDCVSKLVKIAGIIVAA 153
            ..|........|.:      .:::..|.:         |...|:  .::..|...:.:.|.::..
 Frog    77 RAAMSFLQSCSEKQ------TLVMKQNFHARITGLPVCPELTREHIPRTRDVGHFLSVTGTVIRT 135

  Fly   154 SGISAKATRMSIQCLSCSTVIPNLKVNPGLEGYAL---PRKCNTEQAGRPKCPLDPFFIMPDK-- 213
            |.:..........|..|..|:   .|....|.|..   |..|:.|:.    |....|..:.|.
 Frog   136 SLVKVLEYEQDFMCNKCKHVV---TVKADFEQYYTFKPPITCSNEEG----CNSSKFTCLSDSST 193

  Fly   214 -CKCVDFQTLKLQELPDFVPQGEIPRHLQLFCDRSLCERVVPGNRVLIQGIYSIRKVGKPSRRDG 277
             ..|.|:|.:|:||....:..|.|||.:.:..:..|.:....|:.|.:.|:  :.:..||...|.
 Frog   194 PASCRDYQEIKIQEQVQRLSVGSIPRSMIVVLEDDLVDSCKSGDDVTVYGV--VMQRWKPLYIDT 256

  Fly   278 REKAVVGVRAPYMRV-----VGITVDSEGAGAISRYSNITSDEE---EHFRRMAASGDIYERLSQ 334
            |....:.::|.|:.|     .|:.::.|          :..:.|   |.:|.....|  ...:..
 Frog   257 RCDLEIVLKANYIAVNNEQPCGVVINEE----------VRKEYEGFWEKYRNSPLEG--RNEILA 309

  Fly   335 SLAPSIFGSRDIKKAITCMLFGGSRKRLPDGLCRRGDINVLLLGDPGTAKSQLLKFVEKVAPIAV 399
            ||.|.:||...:|.|:..:|.||.::....|...||:.::||:|||||.|||.||:..|:.|.:|
 Frog   310 SLCPQVFGMFVVKLAVAMVLAGGVQRIDSAGTRVRGESHLLLVGDPGTGKSQFLKYAVKITPRSV 374

  Fly   400 YTSGKGSSAAGLTASVMKDPQTRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTI 464
            .|:|.||::||||.:.:||....|  :|.||:||||||:.|||||:.::|.||.:||||||||||
 Frog   375 LTAGIGSTSAGLTVTAVKDSGEWN--LEAGALVLADGGLCCIDEFNSIKEHDRTSIHEAMEQQTI 437

  Fly   465 SIAKAGITTTLNSRCSVLAAANSIFGRWDDTKG-EENIDFMPTILSRFDMIFIVKDIHDESRDIT 528
            |:||||:...||:|.::|||.|. .|::|..:. ..|:.....:|||||::.::.|..:|..|
 Frog   438 SVAKAGLVCKLNTRTTILAATNP-KGQYDPEESISVNVALASPLLSRFDLVLVLLDTKNEDWD-- 499

  Fly   529 LAKHIINVHLSSNKSAPSEPAEGEISLSTFKKYIHYCR-THCGPRLSEAAGEKLKSRYVLMRSGA 592
               .||:..:..:|..|.: ::...|:...|.|  :|. .:..|::|:.|...|...|.|.|.
 Frog   500 ---RIISSFILESKGCPRK-SDKLWSMEKMKTY--FCLIKNLQPKMSQDANVILVRYYQLQRQ-- 556

  Fly   593 GQQEKASDKRLSIPITVRQLEAVIRISESLAKIRLQPFATDEHVNEALRLFQVSTLDAAMTGS-- 655
                  |..|.:...|:|.||::||::|:.|::..:...|.|   :|:.:  ||.::::|.|.
 Frog   557 ------SSCRNAARTTIRLLESLIRLAEAHARLMYRDVVTTE---DAITV--VSIMESSMQGGAL 610

  Fly   656 LAGAEGFTT---EEDQETLN-RIEKQLKRRFAIGSQVSEQNILQDFLRQKYEE 704
            |.|.....|   |..:|... :.|..|:|   :|.|......||...||:.|:
 Frog   611 LGGVNALHTSFPENPREQYRMQCELLLER---LGLQKLLDKELQRLDRQQNED 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm5	NP_524308.2	MCM_N	31..125	CDD:464206	20/89 (22%)
		MCM	128..648	CDD:214631	163/546 (30%)
mcm9	XP_002932153.1	Mcm2	6..606	CDD:440854	184/644 (29%)
		MCM9	306..604	CDD:350666	119/321 (37%)