DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art1 and Prmt3

DIOPT Version :9

Sequence 1:	NP_650017.1	Gene:	Art1 / 41295	FlyBaseID:	FBgn0037834	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_446009.1	Gene:	Prmt3 / 89820	RGDID:	620413	Length:	528	Species:	Rattus norvegicus

Alignment Length:	392	Identity:	168/392 - (42%)
Similarity:	233/392 - (59%)	Gaps:	32/392 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 PMEAAVESATGITPNSNANSN---NVAKKLPAEGS-------------------------TGDNP 43
            |:.|......|::.|::|...   ..|:.|.||.:                         |..:.
  Rat   139 PVSAPFTYPNGLSENTSAVEKLKLMEARALSAEAALARAREDLQKMKQFAQDFVMNVDVRTCSST 203

  Fly    44 NANADEMTSRD-YYFDSYAHFGIHEEMLKDEVRTVTYRNAMYHNKHLFQGKTVLDVGCGTGILSM 107
            ...||.....| .||.||.|:|||||||||:|||.:||:.:|.|.|:|:.|.|||||||||||||
  Rat   204 TTIADLQEDEDGVYFSSYGHYGIHEEMLKDKVRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSM 268

  Fly   108 FAAKAGAAQVIAVDCSNIIEFARQVVIDNNLQDVITVVKGKIEEIELPNGIEGVDIIISEWMGYC 172
            |||||||.:|||||.|.|:..|..::..|.|:|.|.::||||||:.||  :|.||:||||||||.
  Rat   269 FAAKAGAKKVIAVDQSEILYQAMDIIRLNKLEDTIVLIKGKIEEVSLP--VEKVDVIISEWMGYF 331

  Fly   173 LFYESMLDTVLYARDKWLKKDGMMFPDRGTLYITAIEDRQYKDEKINWWDDVYGFDMSCIRKVAV 237
            |.:|||||:||||:.|:|.|.|.::||..|:.:.|:.|.....::|.:|||||||:|||::|..:
  Rat   332 LLFESMLDSVLYAKSKYLAKGGSVYPDICTISLVAVSDVSKHADRIAFWDDVYGFNMSCMKKAVI 396

  Fly   238 TEPLVDVVDPKQVVSTSCMVKEVDLYTVQKADLNFSSKFSLCIKRNDFVQALVTYFNIEFTK-CH 301
            .|.:|:|||.|.::|..|.:|.:|.:|...:||.|||.|:|...:.....|:..||:|.|.| ||
  Rat   397 PEAVVEVVDHKTLISDPCDIKHIDCHTTSISDLEFSSDFTLRTTKTAMCTAVAGYFDIYFEKNCH 461

  Fly   302 KRLGFSTSPDSTYTHWKQTVFYLDDHMTAKKNEEITGTFQMKPNERNNRDLDFVIDINFKGELSQ 366
            .|:.|||.|.||.||||||:|.|:.....|..|.:.|...:..|:::.|.|...:.:|...:...
  Rat   462 NRVVFSTGPQSTKTHWKQTIFLLEKPFPVKAGEALKGKITVHKNKKDPRSLIVTLTLNSSTQTYS 526

  Fly   367 IQ 368
            :|
  Rat   527 LQ 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art1	NP_650017.1	AdoMet_MTases	94..194	CDD:100107	64/99 (65%)
Prmt3	NP_446009.1	zf-C2H2_2	48..>97	CDD:289522
Prmt3	NP_446009.1	AdoMet_MTases	256..356	CDD:100107	65/101 (64%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D432852at33208
OrthoFinder	1	1.000	-	-		FOG0000206
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820