DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art1 and PRMT1A

DIOPT Version :9

Sequence 1:	NP_650017.1	Gene:	Art1 / 41295	FlyBaseID:	FBgn0037834	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_179557.1	Gene:	PRMT1A / 816486	AraportID:	AT2G19670	Length:	366	Species:	Arabidopsis thaliana

Alignment Length:	367	Identity:	195/367 - (53%)
Similarity:	261/367 - (71%)	Gaps:	8/367 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 TGITPNSNANSNNVAKKLPAEGS-----TGDNPNAN-ADEMTSRDYYFDSYAHFGIHEEMLKDEV 74
            |....|:|.:......||..|.:     .||:.||: ||::||.|||||||:|||||||||||.|
plant     2 TSTENNNNGSDETQTTKLHFEDADESMHDGDDNNADVADDITSADYYFDSYSHFGIHEEMLKDVV 66

  Fly    75 RTVTYRNAMYHNKHLFQGKTVLDVGCGTGILSMFAAKAGAAQVIAVDCSNIIEFARQVVIDNNLQ 139
            ||.:|::.:|.||.|.:.|.|||||.||||||:|.||||||.|.||:||.:.:.|:::|..|...
plant    67 RTKSYQDVIYKNKFLIKDKIVLDVGAGTGILSLFCAKAGAAHVYAVECSQMADTAKEIVKSNGFS 131

  Fly   140 DVITVVKGKIEEIELPNGIEGVDIIISEWMGYCLFYESMLDTVLYARDKWLKKDGMMFPDRGTLY 204
            |||||:||||||||||  :..||:||||||||.|.||:|||||||||:|||...|::.||:.:||
plant   132 DVITVLKGKIEEIELP--VPKVDVIISEWMGYFLLYENMLDTVLYARNKWLVDGGIVLPDKASLY 194

  Fly   205 ITAIEDRQYKDEKINWWDDVYGFDMSCIRKVAVTEPLVDVVDPKQVVSTSCMVKEVDLYTVQKAD 269
            :|||||..|||:|:.:||||||||||||::.|:||||||.||..|:|:.|.::|.:|:..:...|
plant   195 VTAIEDAHYKDDKVEFWDDVYGFDMSCIKRRAITEPLVDTVDGNQIVTDSKLLKTMDISKMAAGD 259

  Fly   270 LNFSSKFSLCIKRNDFVQALVTYFNIEFTKCHKRLGFSTSPDSTYTHWKQTVFYLDDHMTAKKNE 334
            .:|::.|.|..:|||.:.|||.||::.||.|||::||||.|.|..|||||||.||:|.:|..:.|
plant   260 ASFTAPFKLVAQRNDHIHALVAYFDVSFTMCHKKMGFSTGPKSRATHWKQTVLYLEDVLTICEGE 324

  Fly   335 EITGTFQMKPNERNNRDLDFVIDINFKGELSQIQESNTYRMR 376
            .|||:..:..|::|.||:|..:..:..|:...|..::.|:||
plant   325 TITGSMTIAQNKKNPRDVDIKLSYSLNGQHCNISRTHFYKMR 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art1	NP_650017.1	AdoMet_MTases	94..194	CDD:100107	66/99 (67%)
PRMT1A	NP_179557.1	AdoMet_MTases	87..187	CDD:100107	67/101 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	198	1.000	Domainoid score	I888
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H21477
Inparanoid	1	1.050	399	1.000	Inparanoid score	I470
OMA	1	1.010	-	-		QHG54098
OrthoDB	1	1.010	-	-		D840669at2759
OrthoFinder	1	1.000	-	-		FOG0000206
OrthoInspector	1	1.000	-	-		otm2423
orthoMCL	1	0.900	-	-		OOG6_101444
Panther	1	1.100	-	-	O	PTHR11006
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1055
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840