DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art1 and prmt2

DIOPT Version :9

Sequence 1:	NP_650017.1	Gene:	Art1 / 41295	FlyBaseID:	FBgn0037834	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	XP_012826019.1	Gene:	prmt2 / 780163	XenbaseID:	XB-GENE-980934	Length:	634	Species:	Xenopus tropicalis

Alignment Length:	351	Identity:	113/351 - (32%)
Similarity:	191/351 - (54%)	Gaps:	15/351 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 NNVAKKLPA---EGSTGDNPNANADEMTSRDYYFDSYAHFGIHEEMLKDEVRTVTYRNAMYHNKH 88
            |.:...:||   ..:..|..:...|:....:.|:.||....:|.|||.|..||..|:..:..|..
Frog   274 NGICGYVPASYLHDALNDQEDTEVDDPWQDEEYYGSYKTLKLHLEMLSDVPRTTAYKEVILRNSS 338

  Fly    89 LFQGKTVLDVGCGTGILSMFAAK-AGAAQVIAVDCSNIIEFARQVVIDNNLQDVITVVKGKIEEI 152
            ...||.:||:||||||:|.|.|| |....|.||:.|.|.|..|::|..|.:.:::.|::.:.||:
Frog   339 SLCGKHILDLGCGTGIISFFCAKLAQPEAVYAVEASEIAEQTRRLVKQNGISNLVHVIRQRAEEL 403

  Fly   153 ELPNGIEGVDIIISEWMGYCLFYESMLDTVLYARDKWLKKDGMMFPDRGTLYITAIEDRQYKDEK 217
            :||.   .|||::|||||.||.:|.||::||.|||:|||:||:|:|....:::......:....|
Frog   404 QLPT---KVDILVSEWMGTCLLFEFMLESVLQARDRWLKEDGVMWPSTACIHLVPCSASKEYANK 465

  Fly   218 INWWDDVYGFDMSCIRKVAVTE----PLVD-VVDPKQVVSTSCMVKEVDLYTVQKADL-NFSSKF 276
            :.:||:.|..|.|.::.:|..|    |..| |:.|:..:|..|::..::|.|:|.|:| ..:|.|
Frog   466 VLFWDNPYQLDFSLLKPLAAKEFFARPKPDYVLQPEDCLSEPCILLHLNLKTLQLAELERMNSDF 530

  Fly   277 SLCIKRNDFVQALVTYFNIEFTKCHK--RLGFSTSPDSTYTHWKQTVFYLDDHMTAKKNEEITGT 339
            :..:..:..:.....:|:::|....:  :|..:|.|.|..||||.|:|.||:.:..:|.::|:|:
Frog   531 TFFVHTDGLLHGFTAWFSVQFQNLEEQGQLELNTGPFSPLTHWKHTLFMLDEPLQVQKGDKISGS 595

  Fly   340 FQMKPNERNNRDLDFVIDINFKGELS 365
            ...:.|....|.:...:.....|:|:
Frog   596 VVFQRNSVWRRHMSVTLSWVINGKLT 621

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art1	NP_650017.1	AdoMet_MTases	94..194	CDD:100107	48/100 (48%)
prmt2	XP_012826019.1	2A1904	<22..>232	CDD:273344
		SH3	235..287	CDD:388381	3/12 (25%)
		Methyltransf_25	345..442	CDD:379312	48/99 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D840669at2759
OrthoFinder	1	1.000	-	-		FOG0000206
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920