DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Art1 and Prmt3

DIOPT Version :9

Sequence 1:	NP_650017.1	Gene:	Art1 / 41295	FlyBaseID:	FBgn0037834	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_598501.1	Gene:	Prmt3 / 71974	MGIID:	1919224	Length:	528	Species:	Mus musculus

Alignment Length:	384	Identity:	167/384 - (43%)
Similarity:	228/384 - (59%)	Gaps:	37/384 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 PNSNANSNNVAKK--------LPAEGS-------------------------TGDNPNANADEMT 51
            ||..:.|.:|.:|        |.||.:                         |..:....||...
Mouse   147 PNGLSESASVVEKLKHMEARALSAEAALARAREDLQKMKQFAQDFVMNVDVRTCSSTTTIADLQE 211

  Fly    52 SRD-YYFDSYAHFGIHEEMLKDEVRTVTYRNAMYHNKHLFQGKTVLDVGCGTGILSMFAAKAGAA 115
            ..| .||.||.|:|||||||||:|||.:||:.:|.|.|:|:.|.|||||||||||||||||.||.
Mouse   212 DEDGVYFSSYGHYGIHEEMLKDKVRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKVGAK 276

  Fly   116 QVIAVDCSNIIEFARQVVIDNNLQDVITVVKGKIEEIELPNGIEGVDIIISEWMGYCLFYESMLD 180
            :|||||.|.|:..|..::..|.|:|.|.::||||||:.||  :|.||:||||||||.|.:|||||
Mouse   277 KVIAVDQSEILYQAMDIIRLNKLEDTIVLIKGKIEEVSLP--VEKVDVIISEWMGYFLLFESMLD 339

  Fly   181 TVLYARDKWLKKDGMMFPDRGTLYITAIEDRQYKDEKINWWDDVYGFDMSCIRKVAVTEPLVDVV 245
            :||||:.|:|.|.|.::||..|:.:.|:.|.....::|.:|||||||:|||::|..:.|.:|:||
Mouse   340 SVLYAKSKYLAKGGSVYPDICTISLVAVSDVSKHADRIAFWDDVYGFNMSCMKKAVIPEAVVEVV 404

  Fly   246 DPKQVVSTSCMVKEVDLYTVQKADLNFSSKFSLCIKRNDFVQALVTYFNIEFTK-CHKRLGFSTS 309
            |.|.::|..|.:|.:|.:|...:||.|||.|:|...:.....|:..||:|.|.| ||.|:.|||.
Mouse   405 DHKTLISDPCDIKHIDCHTTSISDLEFSSDFTLRTTKTAMCTAVAGYFDIYFEKNCHNRVVFSTG 469

  Fly   310 PDSTYTHWKQTVFYLDDHMTAKKNEEITGTFQMKPNERNNRDLDFVIDINFKGELSQIQ 368
            |.||.||||||||.|:.....|..|.:.|...:..|:::.|.|...:.:|...:...:|
Mouse   470 PQSTKTHWKQTVFLLEKPFPVKAGEALKGKITVHKNKKDPRSLIVTLTLNSSTQTYSLQ 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art1	NP_650017.1	AdoMet_MTases	94..194	CDD:100107	63/99 (64%)
Prmt3	NP_598501.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..43
		zf-C2H2_2	48..>97	CDD:289522
		AdoMet_MTases	256..356	CDD:100107	64/101 (63%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D432852at33208
OrthoFinder	1	1.000	-	-		FOG0000206
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820