DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art1 and Prmt8

DIOPT Version :9

Sequence 1:	NP_650017.1	Gene:	Art1 / 41295	FlyBaseID:	FBgn0037834	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_001258314.1	Gene:	Prmt8 / 688502	RGDID:	1587677	Length:	394	Species:	Rattus norvegicus

Alignment Length:	331	Identity:	227/331 - (68%)
Similarity:	286/331 - (86%)	Gaps:	2/331 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 NADEMTSRDYYFDSYAHFGIHEEMLKDEVRTVTYRNAMYHNKHLFQGKTVLDVGCGTGILSMFAA 110
            |.:||||||||||||||||||||||||||||:||||:||||||:|:.|.|||||.||||||||||
  Rat    66 NPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMFAA 130

  Fly   111 KAGAAQVIAVDCSNIIEFARQVVIDNNLQDVITVVKGKIEEIELPNGIEGVDIIISEWMGYCLFY 175
            ||||.:|..::||:|.:::.:::..|:|.:|||:.|||:||:|||  :|.|||||||||||||||
  Rat   131 KAGAKKVFGIECSSISDYSEKIIKANHLDNVITIFKGKVEEVELP--VEKVDIIISEWMGYCLFY 193

  Fly   176 ESMLDTVLYARDKWLKKDGMMFPDRGTLYITAIEDRQYKDEKINWWDDVYGFDMSCIRKVAVTEP 240
            ||||:||::|||||||..|:|||||..||:.|||||||||.||:||::||||||:|||.||:.||
  Rat   194 ESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAMKEP 258

  Fly   241 LVDVVDPKQVVSTSCMVKEVDLYTVQKADLNFSSKFSLCIKRNDFVQALVTYFNIEFTKCHKRLG 305
            |||:|||||||:.:|::||||:|||:..:|:|:|.|.|.|:|||:|.|||||||||||||||::|
  Rat   259 LVDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRNDYVHALVTYFNIEFTKCHKKMG 323

  Fly   306 FSTSPDSTYTHWKQTVFYLDDHMTAKKNEEITGTFQMKPNERNNRDLDFVIDINFKGELSQIQES 370
            |||:||:.|||||||||||:|::|.::.|||.||..||||.:|.|||||.:|::|||:|.:...|
  Rat   324 FSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTVDLDFKGQLCETSVS 388

  Fly   371 NTYRMR 376
            |.|:||
  Rat   389 NDYKMR 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art1	NP_650017.1	AdoMet_MTases	94..194	CDD:100107	65/99 (66%)
Prmt8	NP_001258314.1	AdoMet_MTases	115..215	CDD:100107	66/101 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353636
Domainoid	1	1.000	277	1.000	Domainoid score	I1653
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	504	1.000	Inparanoid score	I1291
OMA	1	1.010	-	-		QHG54098
OrthoDB	1	1.010	-	-		D432852at33208
OrthoFinder	1	1.000	-	-		FOG0000206
OrthoInspector	1	1.000	-	-		otm45356
orthoMCL	1	0.900	-	-		OOG6_101444
Panther	1	1.100	-	-	O	PTHR11006
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1055
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.910