Protein Alignment Art1 and PRMT6

DIOPT Version :10

• Sequence 1: NP_650017.1
• Gene: Art1 / 41295
• FlyBaseID: FBgn0037834
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_060607.2
• Gene: PRMT6 / 55170
• HGNCID: 18241
• Length: 375
• Species: Homo sapiens
• Alignment Length: 371
• Identity: 125/371 - (33%)
• Similarity: 189/371 - (50%)
• Gaps: 46/371 - (12%)

  Fly     7 PMEAAVESATGITPNSNANSNNVAKKLPAEGSTGDNPNANAD--------EMTSRD---YYFDSY 60
            |.:..:||..|                 .||..|......|:        ..|.|:   .|::.|
Human     4 PKKRKLESGGG-----------------GEGGEGTEEEDGAEREAALERPRRTKRERDQLYYECY 51

  Fly    61 AHFGIHEEMLKDEVRTVTYRNAMYHNKHLFQGKTVLDVGCGTGILSMFAAKAGAAQVIAVDCSNI 125
            :...:||||:.|.|||..||..:..|....:||||||||.||||||:|.|:|||.:|.||:.|.|
Human    52 SDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAI 116

  Fly   126 IEFARQVVIDNNLQDVITVVKGKIEEIELPNGIEGVDIIISEWMGYCLFYESMLDTVLYARDKWL 190
            .:.||:||..|.|:|.:.|:.|.:|.:|||   |.||.|:||||||.|.:||||.:||:||.|||
Human   117 WQQAREVVRFNGLEDRVHVLPGPVETVELP---EQVDAIVSEWMGYGLLHESMLSSVLHARTKWL 178

  Fly   191 KKDGMMFPDRGTLYITAIEDRQYKDEKINWWDDV---YGFDMSCIRKVAV------TEPLVDVVD 246
            |:.|::.|....|:|..|.| |..:.::.:|..|   ||.||||:...|.      :|.:|..:.
Human   179 KEGGLLLPASAELFIAPISD-QMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQGLS 242

  Fly   247 PKQVVSTSCMVKEVDLYTV---QKADLNFSSKFSLCIKRNDFVQALVTYFNIEFT--KCHKRLGF 306
            .:.|::......:::|...   |:.:.....:|......:..:.....:|.:.|.  :..|.|..
Human   243 GEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGESEKPLVL 307

  Fly   307 STSPDSTYTHWKQTVFYLDDHMTAKKNEEITGTFQMKPNERNNRDL 352
            ||||....|||||.:.||::.:..:::.:::|...:.|:..|.|.|
Human   308 STSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRL 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Art1	NP_650017.1	COG4076	66..>231	CDD:443253	84/167 (50%)
PRMT6	NP_060607.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		8/50 (16%)
		COG4076	51..>223	CDD:443253	87/175 (50%)