DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art1 and Prmt2

DIOPT Version :9

Sequence 1:	NP_650017.1	Gene:	Art1 / 41295	FlyBaseID:	FBgn0037834	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_001020315.1	Gene:	Prmt2 / 499420	RGDID:	1565519	Length:	445	Species:	Rattus norvegicus

Alignment Length:	300	Identity:	104/300 - (34%)
Similarity:	173/300 - (57%)	Gaps:	13/300 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 YFDSYAHFGIHEEMLKDEVRTVTYRNAMYHNKHLFQGKTVLDVGCGTGILSMFAA-KAGAAQVIA 119
            |||||....:|.|||.|:.||..|.:.:..||...:.|.:|||||||||:|:|.| .|....|.|
  Rat   114 YFDSYGTLKLHLEMLADQPRTTKYHSVILQNKESLKDKVILDVGCGTGIISLFCAHHARPKAVYA 178

  Fly   120 VDCSNIIEFARQVVIDNNLQDVITVVKGKIEEIELPNGIEGVDIIISEWMGYCLFYESMLDTVLY 184
            |:.|::.:...|:|:.|...|.|||.:.|:|::.||   |.||:::|||||.||.:|.|::::||
  Rat   179 VEASDMAQHTGQLVLQNGFADTITVFQQKVEDVVLP---EKVDVLVSEWMGTCLLFEFMIESILY 240

  Fly   185 ARDKWLKKDGMMFPDRGTLYITAIEDRQYKDEKINWWDDVYGFDMSCIRKVAVTE----PLVD-V 244
            |||.|||:||:::|....|::......:....|:.:||:.|.|::|.::.:|:.|    |..: :
  Rat   241 ARDAWLKEDGIIWPTTAALHLVPCSAEKDYHSKVLFWDNAYEFNLSALKSLAIKEFFSRPKSNHI 305

  Fly   245 VDPKQVVSTSCMVKEVDLYTVQKADL-NFSSKFSLCIKRNDFVQALVTYFNIEFTKCHK---RLG 305
            :.|:..:|..|.:.::|:.|||.:|| ....:....|::...:.....:|::.|....:   :..
  Rat   306 LKPEDCLSEPCTILQLDMRTVQVSDLETMRGELRFDIQKAGTLHGFTAWFSVHFQSLEEGQPQQV 370

  Fly   306 FSTSPDSTYTHWKQTVFYLDDHMTAKKNEEITGTFQMKPN 345
            .||.|....||||||:|.:||.:.....:.:||:..::.|
  Rat   371 LSTGPLHPTTHWKQTLFMMDDPVPVHTGDVVTGSVVLQRN 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art1	NP_650017.1	AdoMet_MTases	94..194	CDD:100107	48/100 (48%)
Prmt2	NP_001020315.1	SH3_PRMT2	46..98	CDD:212740
Prmt2	NP_001020315.1	AdoMet_MTases	153..253	CDD:100107	50/102 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D840669at2759
OrthoFinder	1	1.000	-	-		FOG0000206
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820