DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art1 and Art4

DIOPT Version :9

Sequence 1:	NP_650017.1	Gene:	Art1 / 41295	FlyBaseID:	FBgn0037834	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_001262445.1	Gene:	Art4 / 41219	FlyBaseID:	FBgn0037770	Length:	530	Species:	Drosophila melanogaster

Alignment Length:	342	Identity:	130/342 - (38%)
Similarity:	189/342 - (55%)	Gaps:	27/342 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 EMTSRDYYFDSYAHFGIHEEMLKDEVRTVTYRNAMYHNKHLFQGKTVLDVGCGTGILSMFAAKAG 113
            |.:|...||..|.:....:.|::|.|||.||:.|:..|...||.|.|||||.|:||||.||.:||
  Fly   137 EESSASQYFQFYGYLSQQQNMMQDYVRTSTYQRAILGNAVDFQDKIVLDVGAGSGILSFFAVQAG 201

  Fly   114 AAQVIAVDCSNIIEFARQVVIDNNLQDVITVVKGKIEEIELPNGIEGVDIIISEWMGYCLFYESM 178
            ||:|.|::.||:.::|:|:|..||:|..|:|:.|||||||||   |.||:||||.|||.|:.|.|
  Fly   202 AAKVYAIEASNMAQYAQQLVESNNVQHKISVIPGKIEEIELP---EKVDVIISEPMGYMLYNERM 263

  Fly   179 LDTVLYARDKWLKKDGMMFPDRGTLYITAIEDRQYKDEKIN----WWDDVY-GFDMSCIRKVAVT 238
            |:|.|:|| ||||..|.|:|..|.|:|....|.....|:.|    |:...: |.|::.:.|..:.
  Fly   264 LETYLHAR-KWLKPQGKMYPTHGDLHIAPFSDESLYSEQYNKANFWYQSAFHGVDLTTLHKEGMK 327

  Fly   239 E----PLVDVVDPKQVVSTSCMVKEV----DLYTVQKADLN-FSSKFSLCIKRNDFVQALVTYFN 294
            |    |:||..|.:     .||.|.|    |....::.||: .|......|.:......|..:|:
  Fly   328 EYFRQPIVDTFDIR-----ICMAKSVRHVCDFLNDKEDDLHLISIPLEFHILQTGICHGLAFWFD 387

  Fly   295 IEFTKCHKRLGFSTSPDSTYTHWKQTVFYLDDHMTAKKNEEITGTFQMKPNERNNRDLDFVIDIN 359
            :||:...:.:..||||.:..|||.|....|...:..|:.:.:||...::.|.|.:.|:  .||::
  Fly   388 VEFSGSSQNVWLSTSPTAPLTHWYQVRCLLPMPIFIKQGQTLTGRVLLEANRRQSYDV--TIDLH 450

  Fly   360 FKGELSQIQESNTYRMR 376
            .:|.|  |..|||..::
  Fly   451 IEGTL--ISSSNTLDLK 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art1	NP_650017.1	AdoMet_MTases	94..194	CDD:100107	59/99 (60%)
Art4	NP_001262445.1	PH-like	24..134	CDD:302622
		PRMT5	53..430	CDD:282971	117/301 (39%)
		AdoMet_MTases	183..281	CDD:100107	60/101 (59%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440099
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D840669at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11006
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850