DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art1 and prmt1

DIOPT Version :9

Sequence 1:	NP_650017.1	Gene:	Art1 / 41295	FlyBaseID:	FBgn0037834	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_956944.2	Gene:	prmt1 / 321974	ZFINID:	ZDB-GENE-030131-693	Length:	348	Species:	Danio rerio

Alignment Length:	342	Identity:	237/342 - (69%)
Similarity:	297/342 - (86%)	Gaps:	4/342 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 AEGSTGDNPNANADEMTSRDYYFDSYAHFGIHEEMLKDEVRTVTYRNAMYHNKHLFQGKTVLDVG 99
            ::|.:...|  .|::|||:|||||||||||||||||||||||:||||:|:||||||:.|.|||||
Zfish    11 SQGESSAKP--AAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNKHLFKDKVVLDVG 73

  Fly   100 CGTGILSMFAAKAGAAQVIAVDCSNIIEFARQVVIDNNLQDVITVVKGKIEEIELPNGIEGVDII 164
            .|||||.||||||||.:||.::||:|.::|.::|..|.|..::|::|||:||:|||  :|.||||
Zfish    74 SGTGILCMFAAKAGAKKVIGIECSSISDYAVKIVKANKLDHIVTIIKGKVEEVELP--VENVDII 136

  Fly   165 ISEWMGYCLFYESMLDTVLYARDKWLKKDGMMFPDRGTLYITAIEDRQYKDEKINWWDDVYGFDM 229
            |||||||||||||||:||:||||||||.||::||||.|||:||||||||||.||:||::||||||
Zfish   137 ISEWMGYCLFYESMLNTVIYARDKWLKPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDM 201

  Fly   230 SCIRKVAVTEPLVDVVDPKQVVSTSCMVKEVDLYTVQKADLNFSSKFSLCIKRNDFVQALVTYFN 294
            |||::||:||||||||||||:|||:|::||||:|||:..||:|:|.|.|.:||||::.|||||||
Zfish   202 SCIKEVAITEPLVDVVDPKQLVSTACLIKEVDIYTVKIEDLSFTSPFCLQVKRNDYIHALVTYFN 266

  Fly   295 IEFTKCHKRLGFSTSPDSTYTHWKQTVFYLDDHMTAKKNEEITGTFQMKPNERNNRDLDFVIDIN 359
            ||||:||||.||||||:|.|||||||||||||::|.|..|||.||..||||.:|||||||.:||:
Zfish   267 IEFTRCHKRTGFSTSPESPYTHWKQTVFYLDDYLTVKTGEEIFGTISMKPNVKNNRDLDFTVDID 331

  Fly   360 FKGELSQIQESNTYRMR 376
            |||:|.::.:::.||||
Zfish   332 FKGQLCEVSKTSEYRMR 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art1	NP_650017.1	AdoMet_MTases	94..194	CDD:100107	66/99 (67%)
prmt1	NP_956944.2	Methyltransf_18	65..169	CDD:289607	69/105 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	291	1.000	Domainoid score	I1498
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H21477
Inparanoid	1	1.050	519	1.000	Inparanoid score	I1231
OMA	1	1.010	-	-		QHG54098
OrthoDB	1	1.010	-	-		D432852at33208
OrthoFinder	1	1.000	-	-		FOG0000206
OrthoInspector	1	1.000	-	-		otm24487
orthoMCL	1	0.900	-	-		OOG6_101444
Panther	1	1.100	-	-	LDO	PTHR11006
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R58
SonicParanoid	1	1.000	-	-		X1055
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.870